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Full-Text Articles in Physical Sciences and Mathematics
The Photochemistry Of Nitrous Acid In An Aqueous Matrix, Jay S. Ratliff '03
The Photochemistry Of Nitrous Acid In An Aqueous Matrix, Jay S. Ratliff '03
Honors Projects
The thermal and photochemical decomposition of aqueous solutions of nitrous acid and nitrite ion were studied, with a focus on the production and subsequent reaction of hydroxyl radicals. The production of these radicals in aqueous solution may be determined indirectly by disappearance of nitrous acid, or more directly by their interaction with a radical scavenger. Benzene was used to scavenge hydroxyl radical and the products of reactions with hydroxyl radical as well as nitrous acid were characterized. The roles of temperature and dissolved gases were also examined.
Development Of A Simple Method To Detect And Quantify Benzoylecgonine, A Cocaine Metabolite, In Urine, Kylee E. Billings '03
Development Of A Simple Method To Detect And Quantify Benzoylecgonine, A Cocaine Metabolite, In Urine, Kylee E. Billings '03
Honors Projects
Benzoylecgonine (BE) is the most abundant metabolite of cocaine found in the human body. Analysis of BE in urine by gas chromatography/mass spectrometry is the most common method currently used to detect cocaine abuse. This current method is costly and time consuming, so the investigation of an easier and more cost-effective approach is the goal of this research. Because BE is a zwitterion, it is highly soluble in water and very difficult to extract from urine. Once the pKa values of BE are determined, either the cation or anion form of BE can be formed from the zwitterion by adjusting …
Bismuth Compounds In Organic Synthesis. Deprotection Of Ketoximes Using Bismuth Bromide-Bismuth Triflate, Ram Mohan, Joshua Arnold, Patrick Hayes, Robert Kohaus
Bismuth Compounds In Organic Synthesis. Deprotection Of Ketoximes Using Bismuth Bromide-Bismuth Triflate, Ram Mohan, Joshua Arnold, Patrick Hayes, Robert Kohaus
Scholarship
Ketoximes undergo deprotection in CH3CN/acetone/H2O (3:6:1) in the presence of 20–40 mol% BiBr3/5 mol% Bi(OTf)3. Bismuth(III) salts are relatively non-toxic, insensitive to air and inexpensive. These features coupled with the use of a relatively non-toxic solvent system make this method an attractive alternative to existing routes for deprotection of ketoximes.
Bismuth Compounds In Organic Synthesis. Synthesis Of Resorcinarenes Using Bismuth Triflate, Ram Mohan, Katherine Peterson, Russell Smith
Bismuth Compounds In Organic Synthesis. Synthesis Of Resorcinarenes Using Bismuth Triflate, Ram Mohan, Katherine Peterson, Russell Smith
Scholarship
Bismuth triflate (5 mol%) smoothly catalyzes the condensation of aromatic and aliphatic aldehydes with resorcinol to give tetrameric cyclic products, resorcinarenes. With benzaldehyde, the product is obtained as a mixture of two diastereomers and the ratio of the diastereomers depends on reaction time. On the other hand, a single diastereomer is obtained with aliphatic aldehydes. The low toxicity and ease of handling of bismuth compounds coupled with fast reaction times make this method an attractive alternative to the existing methods for resorcinarene formation