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Full-Text Articles in Physical Sciences and Mathematics

Synthesis And Chemistry Of Naphthalene Annulated Trienyl Iron Complexes: Potential Anticancer Dna Alkylation Reagents, Traci Means Jan 2002

Synthesis And Chemistry Of Naphthalene Annulated Trienyl Iron Complexes: Potential Anticancer Dna Alkylation Reagents, Traci Means

Inquiry: The University of Arkansas Undergraduate Research Journal

Iron complex chemistry that opens a new door to the medicinal and pharmaceutical worlds is the aim of this research. Specifically, ortho-quinone methide moieties are intermediates in several antitumor drugs and have been identified as bioreductive alkylators of DNA. In our research, a class of iron compounds has been targeted to resemble these quinone methides. It is hoped that these new compounds could be modified to provide a window of opportunity toward the discovery of a selective mode of drug delivery. We have focused our efforts on generating a reactive transition metal complexed 5-membered ring analog of o-quinone methide based …


Stimulation And Modeling Of Pond Formations On The Asteroid 433 Eros, Justin Thompson Jan 2002

Stimulation And Modeling Of Pond Formations On The Asteroid 433 Eros, Justin Thompson

Inquiry: The University of Arkansas Undergraduate Research Journal

"Ponds" are surface features that appear to be the result of the deposition of finer material on the asteroid's regolith, the layer of loose sediment that blankets the entire asteroid. Ponds were discovered by the NEAR Shoemaker spacecraft in January, 2001, on the asteroid 433 Eros. The objective of experimentation is to simulate the development of these ponds in the Andromeda planetary sciences environmental chamber. The Andromeda Chamber offers a unique ability to simulate surface environments that occur on Eros. The chamber was used to simulate the processes that occur as Eros emits gas through its outer surface, including the …