Physical Sciences and Mathematics Commons^™

A Comparison Of Coalescent Estimation Software, Kristen Piggott Shepherd

Theses and Dissertations

Coalescent theory is a method often used by population geneticists in order to make inferences about evolutionary parameters. The coalescent is a stochastic model that approximates ancestral relationships among genes. An understanding of the coalescent pattern of a sample of sequences, along with some knowledge of the mutations that have occurred, provides information about the evolutionary forces that have acted on the population. Processes such as migration, recombination, variable population size, or natural selection are the forces that affect the genealogies and lead to genetic variability in a sample. Coalescent theory provides a statistical description of the variability in the …