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Full-Text Articles in Physical Sciences and Mathematics
Synthesis Of Fluorinated Proline Analogs For The Potential Inhibition Of Proline Oxidase, Brent Hilbert
Synthesis Of Fluorinated Proline Analogs For The Potential Inhibition Of Proline Oxidase, Brent Hilbert
Honors Theses, 1963-2015
Proline oxidase is an enzyme that has been isolated from the inner membrane of rat liver mitochondria. It is the catalyst in the first step of the metabolic pathway for proline-glutamate interconversion. The enzyme is specific for L-proline which is oxidized to Æ-pyrroline- 5-carboxylic acid. 4,4- difluoro-L-proline has demonstrated irreversible inhibition of proline oxidase. Further kinetic studies of this inhibition need to be performed in order to elucidate a mechanism for the inhibition. Information regarding the site of the oxidation of proline may also be obtained from these studies. New synthetic routes to 4,4-difluoro-L-proline, and the "cis" and "trans" non- …
The Effects Of Nutrient Loading On Plant And Algae Population: A Comparison Study Of East Gemini Lake And Lower Stumpf Lake, Nick Leonard
The Effects Of Nutrient Loading On Plant And Algae Population: A Comparison Study Of East Gemini Lake And Lower Stumpf Lake, Nick Leonard
Honors Theses, 1963-2015
Eutrophication of lakes has become an increasing problem for many bodies of water. By analyzing the nutrients available and the phytoplankton and macrophyte populations, evaluation and differentiation of East Gemini Lake and Stumpf Lake were made concerning their trophic state. This determination allowed for the further understanding of the effect the trophic state has on the flora of an aquatic system. It was determined that East Gemini Lake was eutrophic based on its available nutrients and phytoplankton populations. In contrast, Stumpf Lake was determined to be mesotrophic having lower available nutrients and less phytoplankton population density with fewer major phytoplnakton …
Building A Continuous Wave Titanium Sapphire Laser, Sean Mcclain
Building A Continuous Wave Titanium Sapphire Laser, Sean Mcclain
Honors Theses, 1963-2015
In fulfilling the requirement of a senior thesis, I have constructed and optimized a continuous wave (cw) titanium sapphire laser, loosely based on the designs of other experimenters. A maximum output power of 500 mw at 23. nm was obtained after trying several cavity configurations. The beam characteristics, including wavelength, beam width, power and position stability were found to be sensitively dependent on the pump power, supplied by an argon ion laser.
Numeric Transmission/Cultural Transition, Paul B. Pekarek
Numeric Transmission/Cultural Transition, Paul B. Pekarek
Honors Theses, 1963-2015
This thesis is a study of the computational methods and common use of mathematics during the Middle Ages. It also discusses the cultural transition that was associated with the numeric transition from the Roman numeral system to the Hindu-Arabic numeral system and the numeric systems' corresponding calculation methods in Christian Europe during the late Middle Ages and early Renaissance. I claim that the transition from Roman numerals to Hindu-Arabic numerals was a result of cultural influences. Furthermore, I show that the transition was steady and found its basis in preexisting forms of calculation. I also look at the influences that …
An Exploration Of Doubly Transitive Designs In Affine Space, Michelle Persons
An Exploration Of Doubly Transitive Designs In Affine Space, Michelle Persons
Honors Theses, 1963-2015
Through a combination of linear algebra, geometry, and algebraic structures, one can prove that certain families of geometric designs have groups of automorphisms that are doubly transitive. These geometric designs can be defined as edge colorings of complete graphs. Automorphisms of these geometric designs are permutations of the vertices of the graphs, which are also permutations of the colors of the edges such that given two edges of the same color, their images are also the same color. All cases considered are on the vector space Fn for a field F and the group of automorphisms is a subgroup of …
A Knowledge-Based Approach To Class Scheduling, Mara Zell
A Knowledge-Based Approach To Class Scheduling, Mara Zell
Honors Theses, 1963-2015
A class scheduling application was developed to assist department chairs in producing class schedules each semester. This was accomplished using a knowledge-based system. The system utilized the many constraints involved in the class scheduling process to solve the problem. This application was developed and implemented in an object oriented package called Powerbuilder. Thus, the application is windows based with point and click features. Three trial schedules were produced. These results demonstrate the ability of the application to schedule three types of classes: classes without labs, classes with one lab, and classes with two labs. The end result is that an …
A Spectroscopic Study Of A Rationally Designed Zinc Binding Protein, Jill Funk
A Spectroscopic Study Of A Rationally Designed Zinc Binding Protein, Jill Funk
Honors Theses, 1963-2015
Recently, biomedical science has turned its drug research endeavors towards a philosophy known as rational drug design. Its goal is to avoid the guesswork and instead design and create the exact proteins that are needed. In order for rational drug design to be feasible, a better understanding of protein structure and function needs to be obtained. This research analyses the structure and function of a "rationally" designed mutation of the calcium binding protein parvalbumin. Parvalbumin was chosen because certain aspects of its composition facilitate analysis and in addition, there is extensive data already known about the protein. The mutation involved …
The Integral Quantum Hall Effect, John Jens Ryan
The Integral Quantum Hall Effect, John Jens Ryan
Honors Theses, 1963-2015
Temperature dependencies of the integer quantum Hall effect in an AlGaAs sample are reported. We obtained measurements at temperatures between 2.2 and 4.2 K, and magnetic fields up to 8 T. Shubnikov de Hass oscillations were also observed and analyzed. The relation between dp,/dB, the slopes between Hall plateaus, and temperature was also investigated and found to not fit the T-r~e lationship which others have experimentally found. Dependencies of the Hall plateaus on the magnetic field, Hall current, and the temperature are also investigated.