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Articles 1 - 3 of 3
Full-Text Articles in Physical Sciences and Mathematics
Electron Transfer-Oxy Radical Mechanism For Anti-Cancer Agents: 9-Anilinoacridines, Peter Kovacic, James R. Ames, Michael D. Ryan
Electron Transfer-Oxy Radical Mechanism For Anti-Cancer Agents: 9-Anilinoacridines, Peter Kovacic, James R. Ames, Michael D. Ryan
Chemistry Faculty Research and Publications
A possible mode of action involving electron transfer is advanced for the 9- anilinoacridines. The mechanism entails formation of toxic oxy radicals which destroy the neoplasm. Cyclic voltammetry was performed on iminium type ions derived by protonation of the acridines. Reductions were generally reversible with potentials of about - 0.60 V. Involvement of quinoidal metabolites is also a possibility. The relationship of electrochemical behavior to structure and physiological activity is addressed.
Structure Of L,L-Diphenylarsenanium Bromide Monohydrate, J. A. Campbell, R. Larsen, C. Campana, Sheldon E. Cremer, A. Gamliel
Structure Of L,L-Diphenylarsenanium Bromide Monohydrate, J. A. Campbell, R. Larsen, C. Campana, Sheldon E. Cremer, A. Gamliel
Chemistry Faculty Research and Publications
No abstract provided.
Structure Of L-Benzyl-2,2,3,3-Tetramethyl-L-Phenylphosphetanium Bromide, A Cyelobutane Derivative, J. A. Campbell, R. Larsen, C. Campana, Sheldon E. Cremer
Structure Of L-Benzyl-2,2,3,3-Tetramethyl-L-Phenylphosphetanium Bromide, A Cyelobutane Derivative, J. A. Campbell, R. Larsen, C. Campana, Sheldon E. Cremer
Chemistry Faculty Research and Publications
No abstract provided.