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Trans Diequatorially Fused 3',3'-Diphenyl-2'-Morpholinone Derivatives Of 2-Amino-2-Deoxy-D-Glucose, Julian Guardado Puentes

University of the Pacific Theses and Dissertations

The chemistry of amino sugar compounds has been studied in the last years in connection with the study of natural products, and many of them have been isolated. ^57,17,18 Amino sugars play an important role in biochemistry, forming blocks of homo- and heteropolymers and complex molecules such as microbial polysaccharides, enzymes, gangliosides, glycoproteins, and antibiotics.

This research project had the purpose of preparing a derivative of 2-amino-2-deoxy-D-glucose, with a free hydroxyl group at the anomeric carbon, with the 4,6-positions blocked with the benzylidene cyclic acetal, and the 2,3-positions being blocked by a 3,3-diphenyl-2-morpholinone ring trans diequatorially fused to the amino …