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Full-Text Articles in Physical Sciences and Mathematics
Mathematically Modeling Pcr: An Asymptotic Approximation With Potential For Optimization, Martha J. Garlick
Mathematically Modeling Pcr: An Asymptotic Approximation With Potential For Optimization, Martha J. Garlick
All Graduate Plan B and other Reports, Spring 1920 to Spring 2023
A mathematical model for PCR (Polymerase Chain Reaction) is developed using the law of mass action. Differential equations are written from the chemical equations, preserving the detail of the complementary DNA single strand being extended one bas e pair at a time. The equations for the annealing stage are solved analytically. The method of multiple scales is used to approximate solutions for the extension stage. A map is then developed from the solutions to simulate PCR. The advantage of this model is the ability to use the map to optimize the process. Our results suggest that dynamically optimizing the extension …
Optimization Of Control Source And Error Sensor Locations In Free Field Active Noise Control, Connor Raymond Duke
Optimization Of Control Source And Error Sensor Locations In Free Field Active Noise Control, Connor Raymond Duke
Theses and Dissertations
Previous work has shown that active noise control (ANC) can be applied to axial cooling fans. Optimization of the control source and error sensor placement is desired to maximize the attenuation using ANC. A genetic algorithm was developed to find the optimal placement of control sources for a given primary source. The optimal configuration of control sources around a single primary source was shown to be a linear arrangement of the sources. This holds true for both two-dimensional as well as three-dimensional configurations. The higher-order radiation of the linear arrangement has also been verified experimentally, but the improvement in the …
Discrete Algorithms For Analysis Of Genotype Data, Dumitru Brinza
Discrete Algorithms For Analysis Of Genotype Data, Dumitru Brinza
Computer Science Dissertations
Accessibility of high-throughput genotyping technology makes possible genome-wide association studies for common complex diseases. When dealing with common diseases, it is necessary to search and analyze multiple independent causes resulted from interactions of multiple genes scattered over the entire genome. The optimization formulations for searching disease-associated risk/resistant factors and predicting disease susceptibility for given case-control study have been introduced. Several discrete methods for disease association search exploiting greedy strategy and topological properties of case-control studies have been developed. New disease susceptibility prediction methods based on the developed search methods have been validated on datasets from case-control studies for several common …
Some Geometrical Aspects Of The Cone Linear Complementarity Problem., Madhur Malik Dr.
Some Geometrical Aspects Of The Cone Linear Complementarity Problem., Madhur Malik Dr.
Doctoral Theses
Cone Linear Complementarity ProblemLet V be a finite dimensional real inner product space and K be a closed convex cone in V. Given a linear transformation L : V → V and a vector q ∈ V the cone linear complementarity problem or linear complementarity problem over K, denoted as LCP(K, L, q), is to find a vector x ∈ K such thatL(x) + q ∈ K+ and hx, L(x) + qi = 0,where h., .i denotes an inner product on V and K is the dual cone of K defined as:K∗ := {y ∈ V : hx, yi ≥ …