Physical Sciences and Mathematics Commons^™

Multi-Commodity Flow Models For Logistic Operations Within A Contested Environment, Isabel Strinsky

All Theses

Today's military logistics officers face a difficult challenge, generating route plans for mass deployments within contested environments. The current method of generating route plans is inefficient and does not assess the vulnerability within supply networks and chains. There are few models within the current literature that provide risk-averse solutions for multi-commodity flow models. In this thesis, we discuss two models that have the potential to aid military planners in creating route plans that account for risk and uncertainty. The first model we introduce is a continuous time model with chance constraints. The second model is a two-stage discrete time model …

Creating The Optimal Wedding Seating Chart, Madison Lane

Theses/Capstones/Creative Projects

The purpose of this project is to develop an effective seating arrangement for a wedding reception that enhances the comfort of guests. The ultimate aim is to create a harmonious and enjoyable atmosphere for all attendees. To achieve this, an integer program was designed to optimize the seating arrangement for the author’s upcoming wedding on May 27th, 2023. To ensure accuracy and feasibility, actual feedback was gathered from the guests to evaluate their compatibility and preferences. The proposed seating chart optimization not only addresses the placement of guests but also determines the number of tables required for the reception. The …

Sensitivity Analysis Of Basins Of Attraction For Gradient-Based Optimization Methods, Gillian King

Honors Projects

This project is an analysis of the effectiveness of five distinct optimization methods in their ability in producing clear images of the basins of attraction, which is the set of initial points that approach the same minimum for a given function. Basin images are similar to contour plots, except that they depict the distinct regions of points--in unique colors--that approach the same minimum. Though distinct in goal, contour plots are useful to basin research in that idealized basin images can be inferred from the steepness levels and location of extrema they depict. Effectiveness of the method changes slightly depending on …

Sensitivity Analysis Of Basins Of Attraction For Nelder-Mead, Sonia K. Shah

Honors Projects

The Nelder-Mead optimization method is a numerical method used to find the minimum of an objective function in a multidimensional space. In this paper, we use this method to study functions - specifically functions with three-dimensional graphs - and create images of the basin of attraction of the function. Three different methods are used to create these images named the systematic point method, randomized centroid method, and systemized centroid method. This paper applies these methods to different functions. The first function has two minima with an equivalent function value. The second function has one global minimum and one local minimum. …

Dynamic Nonlinear Gaussian Model For Inferring A Graph Structure On Time Series, Abhinuv Uppal

CMC Senior Theses

In many applications of graph analytics, the optimal graph construction is not always straightforward. I propose a novel algorithm to dynamically infer a graph structure on multiple time series by first imposing a state evolution equation on the graph and deriving the necessary equations to convert it into a maximum likelihood optimization problem. The state evolution equation guarantees that edge weights contain predictive power by construction. After running experiments on simulated data, it appears the required optimization is likely non-convex and does not generally produce results significantly better than randomly tweaking parameters, so it is not feasible to use in …

Optimization Studies And Applications: In Retail Gasoline Market, Daero Kim

Electronic Thesis and Dissertation Repository

The study of the retail gasoline market is of great interest in financial economics, since it allows many theories about price formation, oligopolistic markets, and consumer search to be tested. In addition, the risk management of gasoline prices is an important instance of the management of any consumable commodity cost. For the retailer, the tool of dynamic pricing may be found to be useful.

This thesis contributes to the study of retail gasoline markets in three main ways, each in its own paper. The first paper tests various economic models to confirm earlier results about pricing behavior in retail gasoline …

Network Analytics For The Mirna Regulome And Mirna-Disease Interactions, Joseph Jayakar Nalluri

Theses and Dissertations

miRNAs are non-coding RNAs of approx. 22 nucleotides in length that inhibit gene expression at the post-transcriptional level. By virtue of this gene regulation mechanism, miRNAs play a critical role in several biological processes and patho-physiological conditions, including cancers. miRNA behavior is a result of a multi-level complex interaction network involving miRNA-mRNA, TF-miRNA-gene, and miRNA-chemical interactions; hence the precise patterns through which a miRNA regulates a certain disease(s) are still elusive. Herein, I have developed an integrative genomics methods/pipeline to (i) build a miRNA regulomics and data analytics repository, (ii) create/model these interactions into networks and use optimization techniques, motif …

Modeling And Control Of Nanoparticle Bloodstream Concentration For Cancer Therapies, Scarlett S. Bracey

Doctoral Dissertations

Currently, the most commonly used treatments for cancerous tumors (chemotherapy, radiation, etc.) have almost no method of monitoring the administration of the treatment for adverse effects in real time. Without any real time feedback or control, treatment becomes a "guess and check" method with no way of predicting the effects of the drugs based on the actual bioavailability to the patient's body. One particular drug may be effective for one patient, yet provide no benefit to another. Doctors and scientists do not routinely attempt to quantifiably explain this discrepancy. In this work, mathematical modeling and analysis techniques are joined together …