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Full-Text Articles in Physical Sciences and Mathematics
Sequential Optimization For Stressor-Informed Test Planning Through Integration Of Experimental And Simulated Data, Jacob Brecheisen
Sequential Optimization For Stressor-Informed Test Planning Through Integration Of Experimental And Simulated Data, Jacob Brecheisen
Data Science Undergraduate Honors Theses
This technical report details an innovative approach in reliability engineering aimed at maximizing system durability through a synergistic use of physical experimentation and computer-based modeling. Our methodology explores the efficient design and analysis of computer experiments and physical tests to facilitate accelerated reliability growth, while leveraging a sequential integration of data from these two distinct sources: costly physical experiments, characterized by random errors, and inexpensive computer simulations, marked by inherent systematic errors. The key innovation lies in the adoption of a closed-loop design and analysis method. This method begins by identifying a viable subset of important environmental stressors—such as temperature, …
A Machine Learning Approach For Predicting Clinical Trial Patient Enrollment In Drug Development Portfolio Demand Planning, Ahmed Shoieb
A Machine Learning Approach For Predicting Clinical Trial Patient Enrollment In Drug Development Portfolio Demand Planning, Ahmed Shoieb
Masters Theses
One of the biggest challenges the clinical research industry currently faces is the accurate forecasting of patient enrollment (namely if and when a clinical trial will achieve full enrollment), as the stochastic behavior of enrollment can significantly contribute to delays in the development of new drugs, increases in duration and costs of clinical trials, and the over- or under- estimation of clinical supply. This study proposes a Machine Learning model using a Fully Convolutional Network (FCN) that is trained on a dataset of 100,000 patient enrollment data points including patient age, patient gender, patient disease, investigational product, study phase, blinded …
Energy Planning Model Design For Forecasting The Final Energy Consumption Using Artificial Neural Networks, Haidy Eissa
Energy Planning Model Design For Forecasting The Final Energy Consumption Using Artificial Neural Networks, Haidy Eissa
Theses and Dissertations
“Energy Trilemma” has recently received an increasing concern among policy makers. The trilemma conceptual framework is based on three main dimensions: environmental sustainability, energy equity, and energy security. Energy security reflects a nation’s capability to meet current and future energy demand. Rational energy planning is thus a fundamental aspect to articulate energy policies. The energy system is huge and complex, accordingly in order to guarantee the availability of energy supply, it is necessary to implement strategies on the consumption side. Energy modeling is a tool that helps policy makers and researchers understand the fluctuations in the energy system. Over the …
Optimal Communication Structures For Concurrent Computing, Andrii Berdnikov
Optimal Communication Structures For Concurrent Computing, Andrii Berdnikov
Doctoral Dissertations
This research focuses on communicative solvers that run concurrently and exchange information to improve performance. This “team of solvers” enables individual algorithms to communicate information regarding their progress and intermediate solutions, and allows them to synchronize memory structures with more “successful” counterparts. The result is that fewer nodes spend computational resources on “struggling” processes. The research is focused on optimization of communication structures that maximize algorithmic efficiency using the theoretical framework of Markov chains. Existing research addressing communication between the cooperative solvers on parallel systems lacks generality: Most studies consider a limited number of communication topologies and strategies, while the …
Scheduling Allocation And Inventory Replenishment Problems Under Uncertainty: Applications In Managing Electric Vehicle And Drone Battery Swap Stations, Amin Asadi
Graduate Theses and Dissertations
In this dissertation, motivated by electric vehicle (EV) and drone application growth, we propose novel optimization problems and solution techniques for managing the operations at EV and drone battery swap stations. In Chapter 2, we introduce a novel class of stochastic scheduling allocation and inventory replenishment problems (SAIRP), which determines the recharging, discharging, and replacement decisions at a swap station over time to maximize the expected total profit. We use Markov Decision Process (MDP) to model SAIRPs facing uncertain demands, varying costs, and battery degradation. Considering battery degradation is crucial as it relaxes the assumption that charging/discharging batteries do not …
Warranty Period And Product Price Optimization For Remanufactured Products, Yuxi Liu
Warranty Period And Product Price Optimization For Remanufactured Products, Yuxi Liu
Theses and Dissertations
This study considers a remanufactured electrical product under a tiered warranty policy. Warranty is key in ensuring a good manufacturer—consumer relationship. Manufacturers hope to minimize warranty costs while consumers believe that good warranty promises better product quality and reliability. This Thesis presents an optimal warranty period from the perspective of a manufacturer to maximize the total expected profits, while ensuring sustained consumer relation. We use real data from a local company with a global supply chain to provide a numerical example.
Developing An Optimal Model For Infant Home Visitation, Isaac Atuahene
Developing An Optimal Model For Infant Home Visitation, Isaac Atuahene
Doctoral Dissertations
The United States, Great Britain, Denmark, Canada and many other countries have accepted home visitation (HV) as a promising strategy for interventions for infants after births and for their mothers. Prior HV studies have focused on theoretical foundations, evaluations of programs, cost/benefit analysis and cost estimation by using hospital/payer/insurance data to prove its effectiveness and high cost. As governments and private organizations continue to fund HVs, it is an opportune time to develop and formulate operations research (OR) models of HV coverage, quality and cost so they might be used in program implementation as done for adult home healthcare (HHC) …
Poisson Distributed Individuals Control Charts With Optimal Limits, Negin Enayaty Ahangar
Poisson Distributed Individuals Control Charts With Optimal Limits, Negin Enayaty Ahangar
Graduate Theses and Dissertations
The conventional method used in attribute control charts is the Shewhart three sigma limits. The implicit assumption of the Normal distribution in this approach is not appropriate for skewed distributions such as Poisson, Geometric and Negative Binomial. Normal approximations perform poorly in the tail area of the these distributions. In this research, a type of attribute control chart is introduced to monitor the processes that provide count data. The economic objective of this chart is to minimize the cost of its errors which is determined by the designer. This objective is a linear function of type I and II errors. …
Optimization Of Strategic Planning Processes For Configurable Products: Considerations For Global Supply, Demand, And Sustainability Issues, Edward Lawrence Umpfenbach
Optimization Of Strategic Planning Processes For Configurable Products: Considerations For Global Supply, Demand, And Sustainability Issues, Edward Lawrence Umpfenbach
Wayne State University Dissertations
The assortment planning problem is to decide on the set of products that a retailer or manufacturer will offer to its customers to maximize profitability. While assortment planning research has been expanding in recent years, the current models are inadequate for the needs of a configurable product manufacturer. In particular, we address assortment planning for an automobile manufacturer. We develop models to integrate assortment planning and supply chain management, designed for use by a large automaker in its strategic planning phase. Our model utilizes a multinomial logit model transformed into a mixed integer linear program through the Charnes-Cooper transformation. It …