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Full-Text Articles in Physical Sciences and Mathematics

Optics Studies For Multipass Energy Recovery At Cebaf: Er@Cebaf, Isurumali Neththikumara Oct 2023

Optics Studies For Multipass Energy Recovery At Cebaf: Er@Cebaf, Isurumali Neththikumara

Physics Theses & Dissertations

Energy recovery linacs (ERLs), focus on recycling the kinetic energy of electron beam for the purpose of accelerating a newly injected beam within the same accelerating structure. The rising developments in the super conducting radio frequency technology, ERL technology has achieved several noteworthy milestones over the past few decades. In year 2003, Jefferson Lab has successfully demonstrated a single pass energy recovery at the CEBAF accelerator. Furthermore, they conducted successful experiments with IR-FEL demo and upgrades, as well as the UV FEL driver. This multi-pass, multi-GeV range energy recovery demonstration proposed to be carried out at CEBAF accelerator at Jefferson …


Towards A Robust Defense: A Multifaceted Approach To The Detection And Mitigation Of Neural Backdoor Attacks Through Feature Space Exploration And Analysis, Liuwan Zhu Aug 2023

Towards A Robust Defense: A Multifaceted Approach To The Detection And Mitigation Of Neural Backdoor Attacks Through Feature Space Exploration And Analysis, Liuwan Zhu

Electrical & Computer Engineering Theses & Dissertations

From voice assistants to self-driving vehicles, machine learning(ML), especially deep learning, revolutionizes the way we work and live, through the wide adoption in a broad range of applications. Unfortunately, this widespread use makes deep learning-based systems a desirable target for cyberattacks, such as generating adversarial examples to fool a deep learning system to make wrong decisions. In particular, many recent studies have revealed that attackers can corrupt the training of a deep learning model, e.g., through data poisoning, or distribute a deep learning model they created with “backdoors” planted, e.g., distributed as part of a software library, so that the …


Measurements Of Magnetic Field Penetration Of Materials For Superconducting Radiofrequency Cavities, Iresha Harshani Senevirathne May 2023

Measurements Of Magnetic Field Penetration Of Materials For Superconducting Radiofrequency Cavities, Iresha Harshani Senevirathne

Physics Theses & Dissertations

Superconducting Radio Frequency (SRF) cavities used in particle accelerators are typically formed from or coated with superconducting materials. Currently high purity niobium is the material of choice for SRF cavities which have been optimized to operate near their theoretical field limits. This brings about the need for significant R&D efforts to develop next generation superconducting materials which could outperform Nb and keep up with the demands of new accelerator facilities. To achieve high quality factors and accelerating gradients, the cavity material should be able to remain in the superconducting Meissner state under high RF magnetic field without penetration of quantized …


Applied Deep Learning: Case Studies In Computer Vision And Natural Language Processing, Md Reshad Ul Hoque Aug 2022

Applied Deep Learning: Case Studies In Computer Vision And Natural Language Processing, Md Reshad Ul Hoque

Electrical & Computer Engineering Theses & Dissertations

Deep learning has proved to be successful for many computer vision and natural language processing applications. In this dissertation, three studies have been conducted to show the efficacy of deep learning models for computer vision and natural language processing. In the first study, an efficient deep learning model was proposed for seagrass scar detection in multispectral images which produced robust, accurate scars mappings. In the second study, an arithmetic deep learning model was developed to fuse multi-spectral images collected at different times with different resolutions to generate high-resolution images for downstream tasks including change detection, object detection, and land cover …


Emotion Detection Using An Ensemble Model Trained With Physiological Signals And Inferred Arousal-Valence States, Matthew Nathanael Gray Aug 2022

Emotion Detection Using An Ensemble Model Trained With Physiological Signals And Inferred Arousal-Valence States, Matthew Nathanael Gray

Electrical & Computer Engineering Theses & Dissertations

Affective computing is an exciting and transformative field that is gaining in popularity among psychologists, statisticians, and computer scientists. The ability of a machine to infer human emotion and mood, i.e. affective states, has the potential to greatly improve human-machine interaction in our increasingly digital world. In this work, an ensemble model methodology for detecting human emotions across multiple subjects is outlined. The Continuously Annotated Signals of Emotion (CASE) dataset, which is a dataset of physiological signals labeled with discrete emotions from video stimuli as well as subject-reported continuous emotions, arousal and valence, from the circumplex model, is used for …


Development Of High Quantum Efficiency Strained Superlattice Spin Polarized Photocathodes Via Metal Organic Chemical Vapor Deposition, Benjamin Belfore Aug 2022

Development Of High Quantum Efficiency Strained Superlattice Spin Polarized Photocathodes Via Metal Organic Chemical Vapor Deposition, Benjamin Belfore

Electrical & Computer Engineering Theses & Dissertations

Spin polarized photocathodes are necessary to examine parity violations and other fundamental phenomena in the field of high energy physics. To create these devices, expensive and complicated growth processes are necessary. While integral to accelerator physics, spin polarized electrons could have other exciting applications in materials science and other fields of physics. In order to explore these other applications feasibly, the relative supply of spin polarized photocathodes with a high rate of both polarization and photoemission needs to be increased. One such way to increase this supply is to develop the means to grow them faster and at a larger …


Chen-Fliess Series For Linear Distributed Systems, Natalie T. Pham May 2022

Chen-Fliess Series For Linear Distributed Systems, Natalie T. Pham

Electrical & Computer Engineering Theses & Dissertations

Distributed systems like fluid flow and heat transfer are modeled by partial differential equations (PDEs). In control theory, distributed systems are generally reformulated in terms of a linear state space realization, where the state space is an infinite dimensional Banach space or Hilbert space. In the finite dimension case, the input-output map can always be written in terms of a Chen-Fliess functional series, that is, a weighted sum of iterated integrals of the components of the input function. The Chen-Fliess functional series has been used to describe interconnected nonlinear systems, to solve system inversion and tracking problems, and to design …


Development Of High Conductivity Copper Coatings For Srf Cavity, Himal Pokhrel May 2022

Development Of High Conductivity Copper Coatings For Srf Cavity, Himal Pokhrel

Physics Theses & Dissertations

The development of metallic coatings with high purity and high thermal conductivity at cryogenic temperature could be very important for application to the superconducting radiofrequency (SRF) cavity technology. The deposition of such bulk coatings on the outer surface of a niobium cavity could result in higher heat conductance and mechanical stiffness, both of which are crucial for enhancing the cavity performance at a reduced cost.

Cold spray technology was used to deposit bulk coatings of pure copper and copper-tungsten alloys on the niobium substrate and the samples of size 2 mm × 2 mm cross section were cut and subjected …


Machine Learning Classification Of Digitally Modulated Signals, James A. Latshaw May 2022

Machine Learning Classification Of Digitally Modulated Signals, James A. Latshaw

Electrical & Computer Engineering Theses & Dissertations

Automatic classification of digitally modulated signals is a challenging problem that has traditionally been approached using signal processing tools such as log-likelihood algorithms for signal classification or cyclostationary signal analysis. These approaches are computationally intensive and cumbersome in general, and in recent years alternative approaches that use machine learning have been presented in the literature for automatic classification of digitally modulated signals. This thesis studies deep learning approaches for classifying digitally modulated signals that use deep artificial neural networks in conjunction with the canonical representation of digitally modulated signals in terms of in-phase and quadrature components. Specifically, capsule networks are …


Electromagnetic Modeling Of A Wind Tunnel Magnetic Suspension And Balance System, Desiree Driver May 2022

Electromagnetic Modeling Of A Wind Tunnel Magnetic Suspension And Balance System, Desiree Driver

Mechanical & Aerospace Engineering Theses & Dissertations

Wind tunnels are used to study forces and moments acting on an aerodynamic body. While most results involve some interference from the mechanical supports used to hold the model, a Magnetic Suspension and Balance System (MSBS) is void of these interferences and presents an ideal test scenario. To further investigate the feasibility of dynamic stability testing at supersonic speeds using a MSBS, a preliminary design idea is currently being developed using an existing MSBS in a subsonic wind tunnel. This review focuses on the development of a mathematical model to more accurately portray the capabilities of the 6 inch Massachusetts …


A Digital One Degree Of Freedom Model Of An Electromagnetic Position Sensor, Michelle Elizabeth Weinmann Jul 2021

A Digital One Degree Of Freedom Model Of An Electromagnetic Position Sensor, Michelle Elizabeth Weinmann

Mechanical & Aerospace Engineering Theses & Dissertations

The purpose of this project was to improve an existing system currently in use by NASA Langley Research Center (LaRC). The 6-inch Magnetic Suspension and Balance System (MSBS) built at MIT is operational with control in three degrees of freedom, with two additional degrees of freedom exhibiting passive stability. The means for measuring model displacement within the magnetic environment is an Electromagnetic Position Sensor (EPS), consisting of excitation coils at 20 kHz and multiple sets of pickup coils. The pickup coil voltages are proportional to model displacement in each degree of freedom. However, the EPS electronic signal processing system is …


Wiener-Fliess Composition Of Formal Power Series: Additive Static Feedback And Shuffle Rational Series, Subbarao Venkatesh Guggilam Jul 2021

Wiener-Fliess Composition Of Formal Power Series: Additive Static Feedback And Shuffle Rational Series, Subbarao Venkatesh Guggilam

Electrical & Computer Engineering Theses & Dissertations

The problem statement for this dissertation is two-fold. The first problem considered is when does a Chen-Fliess series in an additive static feedback connection with a formal static map yield a closed-loop system with a Chen-Fliess series expansion? This work proves that such a closed-loop system always has a Chen-Fliess series representation. Furthermore, an algorithm based on the Hopf algebras for the shuffle group and the dynamic output feedback group is designed to compute the generating series of the closed-loop system. It is proved that the additive static feedback connection preserves local convergence and relative degree, but a counterexample shows …


Electrostatic Design And Characterization Of A 200 Kev Photogun And Wien Spin Rotator, Gabriel G. Palacios Serrano Apr 2021

Electrostatic Design And Characterization Of A 200 Kev Photogun And Wien Spin Rotator, Gabriel G. Palacios Serrano

Electrical & Computer Engineering Theses & Dissertations

High-energy nuclear physics experiments at the Jefferson Lab Continuous Electron Beam Accelerator Facility (CEBAF) require high spin-polarization electron beams produced from strained super-lattice GaAs photocathodes activated to negative electron affinity in a high voltage photogun operating at 130 kV dc. A pair of Wien filter spin rotators in the injector provides precise control of the electron beam polarization at the end station target. An upgrade of the CEBAF injector to better support the upcoming Moller experiment requires increasing the electron beam energy to 200 keV, resulting in better transmission through injector apertures and improved photocathode lifetime. In addition, the energy …


Commissioning & Characterization Of Magnetized Gridded Thermionic Electron Source, Mark Stefani Apr 2021

Commissioning & Characterization Of Magnetized Gridded Thermionic Electron Source, Mark Stefani

Electrical & Computer Engineering Theses & Dissertations

Collaborative efforts to design and fabricate a magnetized gridded thermionic electron source have been conducted between Xelera and Jefferson Lab. Commissioning and characterization of an electron gun fabricated by Xelera was performed to benchmark the viability of future electron source designs and capabilities. The work involved simulation, installation, trouble-shooting, modifications of the design, commissioning, characterization, and magnetization of the electron beam produced. A specially designed cavity as well as novel diagnostic tools and methods were developed, implemented, and experimentally tested. Finally, the gun was used to demonstrate a previously unachieved current of magnetized electron beam from a gridded thermionic source …


Deep Cellular Recurrent Neural Architecture For Efficient Multidimensional Time-Series Data Processing, Lasitha S. Vidyaratne Apr 2020

Deep Cellular Recurrent Neural Architecture For Efficient Multidimensional Time-Series Data Processing, Lasitha S. Vidyaratne

Electrical & Computer Engineering Theses & Dissertations

Efficient processing of time series data is a fundamental yet challenging problem in pattern recognition. Though recent developments in machine learning and deep learning have enabled remarkable improvements in processing large scale datasets in many application domains, most are designed and regulated to handle inputs that are static in time. Many real-world data, such as in biomedical, surveillance and security, financial, manufacturing and engineering applications, are rarely static in time, and demand models able to recognize patterns in both space and time. Current machine learning (ML) and deep learning (DL) models adapted for time series processing tend to grow in …


Demonstration Of Visible And Near Infrared Raman Spectrometers And Improved Matched Filter Model For Analysis Of Combined Raman Signals, Alexander Matthew Atkinson Oct 2019

Demonstration Of Visible And Near Infrared Raman Spectrometers And Improved Matched Filter Model For Analysis Of Combined Raman Signals, Alexander Matthew Atkinson

Electrical & Computer Engineering Theses & Dissertations

Raman spectroscopy is a powerful analysis technique that has found applications in fields such as analytical chemistry, planetary sciences, and medical diagnostics. Recent studies have shown that analysis of Raman spectral profiles can be greatly assisted by use of computational models with achievements including high accuracy pure sample classification with imbalanced data sets and detection of ideal sample deviations for pharmaceutical quality control. The adoption of automated methods is a necessary step in streamlining the analysis process as Raman hardware becomes more advanced. Due to limits in the architectures of current machine learning based Raman classification models, transfer from pure …


Laser-Spark Multicharged Ion Implantation System ‒ Application In Ion Implantation And Neural Deposition Of Carbon In Nickel (111), Oguzhan Balki Oct 2019

Laser-Spark Multicharged Ion Implantation System ‒ Application In Ion Implantation And Neural Deposition Of Carbon In Nickel (111), Oguzhan Balki

Electrical & Computer Engineering Theses & Dissertations

Carbon ions generated by ablation of a carbon target using an Nd:YAG laser pulse (wavelength λ = 1064 nm, pulse width τ = 7 ns, and laser fluence of 10-110 J/cm2) are characterized. Time-of-flight analyzer, a three-mesh retarding field analyzer, and an electrostatic ion energy analyzer are used to study the charge and energy of carbon ions generated by laser ablation. The dependencies of the ion signal on the laser fluence, laser focal point position relative to target surface, and the acceleration voltage are described. Up to C4+ are observed. When no acceleration voltage is applied between …


Pulse Power Effects On Transient Plasma Ignition For Combustion, David Wayne Alderman Ii Oct 2019

Pulse Power Effects On Transient Plasma Ignition For Combustion, David Wayne Alderman Ii

Electrical & Computer Engineering Theses & Dissertations

Transient plasma ignition (TPI) uses highly non-equilibrium plasmas, driven by less than 100 nanosecond, high-voltage pulses, to initiate combustion. The effects of pulse repetition frequency (PRF) and ultrashort nanosecond rise times on TPI are investigated in this work using lean, stoichiometric, and rich air-fuel mixtures at atmospheric pressure. Experimental data show the transient plasmas driven by ultrashort rise time, high voltage pulses at high PRF’s enhance the combustion of lean or stoichiometric air-methane mixtures in a static chamber. In particular, increasing PRF enhances the combustion performance by means of reduced delay times independent of the equivalence ratio of the air-fuel …


Variable Speed Limit Control At Sag Curves Through Connected Vehicles: Implications Of Alternative Communications And Sensing Technologies, Reza Vatani Nezafat Apr 2019

Variable Speed Limit Control At Sag Curves Through Connected Vehicles: Implications Of Alternative Communications And Sensing Technologies, Reza Vatani Nezafat

Civil & Environmental Engineering Theses & Dissertations

Connected vehicles (CVs) will enable new applications to improve traffic flow. This study’s focus is to investigate how potential implementation of variable speed limit (VSL) through different types of communication and sensing technologies on CVs may improve traffic flow at a sag curve. At sag curves, the gradient changes from negative to positive values which causes a reduction in the roadway capacity and congestion. A VSL algorithm is developed and implemented in a simulation environment for controlling the inflow of vehicles to a sag curve on a freeway to minimize delays and increase throughput. Both vehicle-to-vehicle (V2V) and infrastructure-to-vehicle (I2V) …


On Analytic Nonlinear Input-Output Systems: Expanded Global Convergence And System Interconnections, Irina M. Winter Arboleda Apr 2019

On Analytic Nonlinear Input-Output Systems: Expanded Global Convergence And System Interconnections, Irina M. Winter Arboleda

Electrical & Computer Engineering Theses & Dissertations

Functional series representations of nonlinear systems first appeared in engineering in the early 1950’s. One common representation of a nonlinear input-output system are Chen-Fliess series or Fliess operators. Such operators are described by functional series indexed by words over a noncommutative alphabet. They can be viewed as a noncommutative generalization of a Taylor series. A Fliess operator is said to be globally convergent when its radius of convergence is infinite, in other words, when there is no a priori upper bound on both the L1-norm of an admissible input and the length of time over which the corresponding output is …


Generation Of Large-Volume Diffuse Plasma By An External Ionization Wave From A Single-Electrode Plasma Jet, Seyed Hamid Razavi Barzoki Jul 2018

Generation Of Large-Volume Diffuse Plasma By An External Ionization Wave From A Single-Electrode Plasma Jet, Seyed Hamid Razavi Barzoki

Electrical & Computer Engineering Theses & Dissertations

A non-thermal transient diffuse plasma can be generated remotely in a nonconductive reduced pressure chamber by an external guided fast ionization wave (FIW). We found that an atmospheric-pressure low-temperature plasma jet (APPJ) can be a source of FIW which transfers an enhanced electric field at the wave front across a reduced pressure Pyrex glass chamber with no electrical connection to the chamber. Here, we studied the formation and propagation of the APPJ plasma, the interaction of atmospheric-pressure guided FIW with a dielectric surface which forms the wall of the reduced-pressure system, and the formation and propagation of the reduce-pressure FIW …


Non-Destructive Evaluation For Composite Material, Desalegn Temesgen Delelegn Jul 2018

Non-Destructive Evaluation For Composite Material, Desalegn Temesgen Delelegn

Electrical & Computer Engineering Theses & Dissertations

The Nondestructive Evaluation Sciences Branch (NESB) at the National Aeronautics and Space Administration (NASA) Langley Research Center (LaRC) has conducted impact damage experiments over the past few years with the goal of understanding structural defects in composite materials. The Data Science Team within the NASA LaRC Office of the Chief Information Officer (OCIO) has been working with the Non-Destructive Evaluation (NDE) subject matter experts (SMEs), Dr. Cheryl Rose, from the Structural Mechanics & Concepts Branch and Dr. William Winfree, from the Research Directorate, to develop computer vision solutions using digital image processing and machine learning techniques that can help identify …


Analysis Of Bulk Power System Resilience Using Vulnerability Graph, Md Ariful Haque Jul 2018

Analysis Of Bulk Power System Resilience Using Vulnerability Graph, Md Ariful Haque

Computational Modeling & Simulation Engineering Theses & Dissertations

Critical infrastructure such as a Bulk Power System (BPS) should have some quantifiable measure of resiliency and definite rule-sets to achieve a certain resilience value. Industrial Control System (ICS) and Supervisory Control and Data Acquisition (SCADA) networks are integral parts of BPS. BPS or ICS are themselves not vulnerable because of their proprietary technology, but when the control network and the corporate network need to have communications for performance measurements and reporting, the ICS or BPS become vulnerable to cyber-attacks. Thus, a systematic way of quantifying resiliency and identifying crucial nodes in the network is critical for addressing the cyber …


Statistical Analysis And Comparison Of Optical Classification Of Atmospheric Aerosol Lidar Data, Kwasi Gyening Afrifa May 2018

Statistical Analysis And Comparison Of Optical Classification Of Atmospheric Aerosol Lidar Data, Kwasi Gyening Afrifa

Electrical & Computer Engineering Projects for D. Eng. Degree

This dissertation presents a new study for the analysis and classification of atmospheric aerosols in remote sensing LIDAR data. Information on particle size and associated properties are extracted from these remote sensing atmospheric data which are collected by a ground-based LIDAR system. This study first considers optical LIDAR parameter-based classification methods for clustering and classification of different types of harmful aerosol particles in the atmosphere. Since accurate methods for aerosol prediction behaviors are based upon observed data, computational approaches must overcome design limitations, and also consider appropriate calibration and estimation accuracy. Consequently, two statistical methods based on generalized linear models …


Development Of A Laser-Spark Multicharged Ion System – Application In Shallow Implantation Of Sic By Boron And Barium, Md. Haider Ali Shaim Jan 2018

Development Of A Laser-Spark Multicharged Ion System – Application In Shallow Implantation Of Sic By Boron And Barium, Md. Haider Ali Shaim

Electrical & Computer Engineering Theses & Dissertations

A novel multicharged ion source, using laser ablation induced plasma coupled with spark discharge, has been investigated in this work. The designed and demonstrated ion source is cost-effective, compact and versatile. Experiments are described with the intention of demonstrating the practicability of ion implantation via laser ion source.

Multicharged aluminum ions are generated by a ns Q-switched Nd:YAG laser pulse ablation of an aluminum target in an ultrahigh vacuum. The experiments are conducted using laser pulse energies of 45–90 mJ focused on the Al target surface by a lens with an 80-cm focal length to 0.0024 cm2 spot area …


Speech Based Machine Learning Models For Emotional State Recognition And Ptsd Detection, Debrup Banerjee Jul 2017

Speech Based Machine Learning Models For Emotional State Recognition And Ptsd Detection, Debrup Banerjee

Electrical & Computer Engineering Theses & Dissertations

Recognition of emotional state and diagnosis of trauma related illnesses such as posttraumatic stress disorder (PTSD) using speech signals have been active research topics over the past decade. A typical emotion recognition system consists of three components: speech segmentation, feature extraction and emotion identification. Various speech features have been developed for emotional state recognition which can be divided into three categories, namely, excitation, vocal tract and prosodic. However, the capabilities of different feature categories and advanced machine learning techniques have not been fully explored for emotion recognition and PTSD diagnosis. For PTSD assessment, clinical diagnosis through structured interviews is a …


Low Temperature Plasma For The Treatment Of Epithelial Cancer Cells, Soheila Mohades Apr 2017

Low Temperature Plasma For The Treatment Of Epithelial Cancer Cells, Soheila Mohades

Electrical & Computer Engineering Theses & Dissertations

Biomedical applications of low temperature plasmas (LTP) may lead to a paradigm shift in treating various diseases by conducting fundamental research on the effects of LTP on cells, tissues, organisms (plants, insects, and microorganisms). This is a rapidly growing interdisciplinary research field that involves engineering, physics, life sciences, and chemistry to find novel solutions for urgent medical needs. Effects of different LTP sources have shown the anti-tumor properties of plasma exposure; however, there are still many unknowns about the interaction of plasma with eukaryotic cells which must be elucidated in order to evaluate the practical potential of plasma in cancer …


Numerical Studies And Optimization Of Magnetron With Diffraction Output (Mdo) Using Particle-In-Cell Simulations, Alireza Majzoobi Oct 2015

Numerical Studies And Optimization Of Magnetron With Diffraction Output (Mdo) Using Particle-In-Cell Simulations, Alireza Majzoobi

Electrical & Computer Engineering Theses & Dissertations

The first magnetron as a vacuum-tube device, capable of generating microwaves, was invented in 1913. This thesis research focuses on numerical simulation-based analysis of magnetron performance. The particle-in-cell (PIC) based MAGIC software tool has been utilized to study the A6 and the Rising-Sun magnetron structures, and to obtain the optimized geometry for optimizing the device performance. The A6 magnetron is the more traditional structure and has been studied more often. The Rising-Sun geometry, consists of two alternating groups of short and long vanes in angular orientation, and was created to achieve mode stability.

The effect of endcaps, changes in lengths …


Development Of Superconducting Spoke Cavities For High-Velocity Applications, Christopher Shawn Hopper Apr 2015

Development Of Superconducting Spoke Cavities For High-Velocity Applications, Christopher Shawn Hopper

Physics Theses & Dissertations

To date, superconducting spoke cavities have been designed, developed, and tested for particle velocities up to β0 ~ 0.6, but there is a growing interest in possible applications of spoke cavities for high-velocity applications. The first task is to explore the design parameter space for low-frequency, high-velocity, single- and double-spoke superconducting cavities in order to determine how each design parameter affects the electromagnetic properties, in particular the surface electromagnetic fields and the shunt impedance. Once an electromagnetically optimized, high-velocity spoke cavity is designed, there are several other characteristics that need to be investigated. These include multipacting scenarios, higher-order mode excitation …


Multi-Surface Simplex Spine Segmentation For Spine Surgery Simulation And Planning, Rabia Haq Jan 2015

Multi-Surface Simplex Spine Segmentation For Spine Surgery Simulation And Planning, Rabia Haq

Computational Modeling & Simulation Engineering Theses & Dissertations

This research proposes to develop a knowledge-based multi-surface simplex deformable model for segmentation of healthy as well as pathological lumbar spine data. It aims to provide a more accurate and robust segmentation scheme for identification of intervertebral disc pathologies to assist with spine surgery planning. A robust technique that combines multi-surface and shape statistics-aware variants of the deformable simplex model is presented. Statistical shape variation within the dataset has been captured by application of principal component analysis and incorporated during the segmentation process to refine results. In the case where shape statistics hinder detection of the pathological region, user-assistance is …