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Physical Sciences and Mathematics Commons

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Theses/Dissertations

Statistics and Probability

Dissertations

2001

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Full-Text Articles in Physical Sciences and Mathematics

Empirical Spectral Analysis Of Random Number Generators, David Zeitler Aug 2001

Empirical Spectral Analysis Of Random Number Generators, David Zeitler

Dissertations

Computer simulation procedures have become a staple of research and development in many fields, including statistics. The generation of pseudo random number sequences is the core of computer simulation procedures. Validity of research results often depend on the underlying validity of the generator being used.

In this work we develop the machinery for a class of tests of spatial uniformity based on a multi-dimensional Fourier transform of the empirical probability density function. The test can be adapted to specific requirements and has the added advantage that it has computational complexity that is relatively independent of the number of data points …


A Comparison Of Methods For Detection Of Qualitative Interaction In Multicenter Trials, Boyd Jay Hanson Apr 2001

A Comparison Of Methods For Detection Of Qualitative Interaction In Multicenter Trials, Boyd Jay Hanson

Dissertations

This research evaluated and compared three methods for the detection of qualitative treatment-by-center interaction proposed by Azzalini and Cox, Gail and Simon and Ciminera et al., through the analysis of simulated data for multicenter studies of two and three centers with two treatments. The effect of unequal sample size and the presence of an overall treatment effect on characteristics of the methods were examined.

The approach, underlying assumptions and theory of the three methods differ. For this study, they were adapted to establish a common basis for evaluation, thus allowing a meaningful comparison of the methods. For the test presented …