Physical Sciences and Mathematics Commons^™

Microcantilever Surface Modification For Chem-/Bio-Sensing, Hongwei Du

Doctoral Dissertations

One focus of the microcantilever (MCL) sensing area is to develop a novel surface modification approach to increase the microcantilever bending amplitudes and thus further improve sensitivities. In this dissertation, enzyme incorporated using the Layer by-Layer (LbL) process, LbL deposition of micro-, nano-hydrogel particles and electrophoretic deposition (EPD) of micro-, nano-hydrogel particles were applied to prepare a multilayer or thin hydrogel films on the surface of microcantilevers. Prior to applying to the microcantilevers, LbL and electrophoretic deposition techniques were also applied to gold coated silicon wafer surfaces to investigate the feasibility and deposition behavior using these techniques. The multilayers prepared …