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Physical Sciences and Mathematics Commons

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Theses/Dissertations

Chemistry

2004

Affinity distribution

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New Insights Into The Binding Site Formation And The Performance Of Molecularly Imprinted Polymers, Hyunjung Kim Jan 2004

New Insights Into The Binding Site Formation And The Performance Of Molecularly Imprinted Polymers, Hyunjung Kim

LSU Doctoral Dissertations

Molecularly imprinted polymers (MIPs) are finding important applications in the field of separation science, catalysis, sensor, and immunoassays. To optimize the performance of the MIPs, it is essential to understand the underlying mechanism of the process. This research focuses on understanding binding site formation and performance, and improvement of the MIPs. Chapter 1 introduces the concept of the MIPs, and binding isotherm and affinity distribution of heterogeneous binding sites in the MIPs. Chapter 2 describes fundamental studies conducted to understand the binding site formation of the MIPs. The number of binding sites (N) and the number average association constant (Kn) …