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Articles 1 - 4 of 4
Full-Text Articles in Physical Sciences and Mathematics
Controlling The Hydrophilicity And Cohesion During Deposition Of Highly Oriented Type I Collagen Films: An Approach For Biomedical Applications, Karina Ambrock, Bernd Grohe, Silvia Mittler
Controlling The Hydrophilicity And Cohesion During Deposition Of Highly Oriented Type I Collagen Films: An Approach For Biomedical Applications, Karina Ambrock, Bernd Grohe, Silvia Mittler
Physics and Astronomy Publications
Using the Langmuir-Blodgett (LB) technology we have pioneered a straightforward and low-cost approach to fabricate highly oriented collagen in thin film format (thickness: ~20 nm, surface areas: 2.5 x ~6.0 cm). An important factor for the use of these films is their cohesion under various conditions. Film formation was studied by coating hydrophilic or hydrophobic glass substrates. The fresh or aged (2 ½ years, -18°C.) collagen solutions used for this purpose either contained collagen network-stabilizing agents (n-propanol or phosphate ions) or were prepared without these stabilizers. Film formation on the air/water interface was analyzed by pressure-area isotherms. Maximum surface pressures …
Strategies For Detecting Biological Molecules On Titan, Catherine Neish, Ralph Lorenz, Elizabeth Turtle, Jason Barnes, Melissa Trainer, Bryan Stiles, Randolph Kirk, Charles Hibbitts, Michael Malaska
Strategies For Detecting Biological Molecules On Titan, Catherine Neish, Ralph Lorenz, Elizabeth Turtle, Jason Barnes, Melissa Trainer, Bryan Stiles, Randolph Kirk, Charles Hibbitts, Michael Malaska
Earth Sciences Publications
Saturn’s moon Titan has all the ingredients needed to produce “life as we know it”. When exposed to liquid water, organic molecules analogous to those found on Titan produce a range of biomolecules such as amino acids. Titan thus provides a natural laboratory for studying the products of prebiotic chemistry. In this work, we examine the ideal locales to search for evidence of, or progression towards, life on Titan. We determine that the best sites to identify biological molecules are deposits of impact melt on the floors of large, fresh impact craters, specifically Sinlap, Selk, and Menrva craters. We find …
A Mass-Producible And Versatile Sensing System: Localized Surface Plasmon Resonance Excited By Individual Waveguide Modes, Zhutian Ding, James M. Stubbs, Danielle Mcrae, Johanna M. Blacquiere, François Lagugné-Labarthet, Silvia Mittler
A Mass-Producible And Versatile Sensing System: Localized Surface Plasmon Resonance Excited By Individual Waveguide Modes, Zhutian Ding, James M. Stubbs, Danielle Mcrae, Johanna M. Blacquiere, François Lagugné-Labarthet, Silvia Mittler
Physics and Astronomy Publications
A plasmonic sensing system that allows the excitation of localized surface plasmon resonance (LSPR) by individual waveguide modes is presented conceptually and experimentally. Any change in the local environment of the gold nanoparticles (AuNPs) alters the degree of coupling between LSPR and a polymer slab waveguide, which then modulates the transmission-output signal. In comparison to conventional LSPR sensors, this system is less susceptible to optical noise and positional variation of signals. Moreover, it enables more freedom in the exploitation of plasmonic hot spots with both transverse electric (TE) and transverse magnetic (TM) modes. Through real-time measurement, it is demonstrated that …
Narrowing Of Plasmon Resonance Peaks As An Ensemble Effect, Zhutian Ding, James M. Stubbs, Silvia Mittler
Narrowing Of Plasmon Resonance Peaks As An Ensemble Effect, Zhutian Ding, James M. Stubbs, Silvia Mittler
Physics and Astronomy Publications
The frequency of localized surface plasmon resonance (LSPR) displayed by gold nanoparticles (AuNPs) redshifts as a function of their local refractive index, which renders them valuable transducers for sensing applications. An ensemble hypothesis is presented herein, along with spectroscopic evidence, using the biotin-streptavidin system on immobilized AuNPs to interpret the decrease in ensemble linewidth (ELW) consistently observed upon functionalization of plasmonic nanoparticles and the subsequent analyte binding. These results demonstrate that ELW can be used to monitor recognition reactions, providing spectral details and a possible sensitivity enhancement to the conventional wavelength sensing. A novel sensing platform allowing the simultaneous measurement …