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Full-Text Articles in Physical Sciences and Mathematics
Design And Fabrication Of A Cop-Based Microfluidic Chip: Chronoamperometric Detection Of Troponin T, Llibertat Abad, Francisco Javier Del Campo, Francesc Xavier Munoz, Luis J Fernandez, Daniel Calavia, Gloria Colom, Juan P Salvador, Maria Pilar Marco, Vanessa Escamilla-Gomez, Berta Esteban-Fernandez De Avila, Susana Campuzano, Maria Pedrero, Jose M Pingarron, Neus Godino, Robert Gorkin Iii, Jens Ducree
Design And Fabrication Of A Cop-Based Microfluidic Chip: Chronoamperometric Detection Of Troponin T, Llibertat Abad, Francisco Javier Del Campo, Francesc Xavier Munoz, Luis J Fernandez, Daniel Calavia, Gloria Colom, Juan P Salvador, Maria Pilar Marco, Vanessa Escamilla-Gomez, Berta Esteban-Fernandez De Avila, Susana Campuzano, Maria Pedrero, Jose M Pingarron, Neus Godino, Robert Gorkin Iii, Jens Ducree
Robert Gorkin III
This work demonstrates the design and fabrication of an all cyclo-olefin polymer based microfluidic device capable of capturing magnetic beads and performing electrochemical detection in a series of gold electrodes. The size of chip is of a microscope slide and features six independent measuring cells formultianalyte detection purposes. The aim of this work is to show that rapid prototyping techniques can be instrumental in the development of novel bioassays, particularly in clinical diagnosis applications. We show the successful determination of troponin-T, a cardiac disease marker, in the clinically relevant range of 0.05–1.0 ng/mL. This methodology achieves a detection limit of …
Fabricating Electrodes For Amperometric Detection In Hybrid Paper/Polymer Lab-On-A-Chip Devices, Neus Godino, Robert Gorkin Iii, Ken Bourke, Jens Ducree
Fabricating Electrodes For Amperometric Detection In Hybrid Paper/Polymer Lab-On-A-Chip Devices, Neus Godino, Robert Gorkin Iii, Ken Bourke, Jens Ducree
Robert Gorkin III
We present a novel, low-resource fabrication and assembly method for creating disposable amperometric detectors in hybrid paper-polymer devices. Currently, mere paper-based microfluidics is far from being able to achieve the same level of process control and integration as state-of-the-art microfluidic devices made of polymers. To overcome this limitation, in this work both substrate types are synergistically combined through a hybrid, multi-component/multi-material system assembly. Using established inkjet wax printing, we transform the paper into a profoundly hydrophobic substrate in order to create carbon electrodes which are simply patterned from carbon inks via custom made adhesive stencils. By virtue of the compressibility …
Pattern Recognition For Detecting Failures In Space Solar Power Systems, Allen Mcdermott, Cameron Kerbaugh, Jeremy Straub, Eunjin Kim
Pattern Recognition For Detecting Failures In Space Solar Power Systems, Allen Mcdermott, Cameron Kerbaugh, Jeremy Straub, Eunjin Kim
Jeremy Straub
This poster covers work relating to the use of expert systems and pattern recognition to attempt to identify, detect and prospectively stop patterns of activity that could potentially lead to failure of a space solar power (SSP) system. A database-based expert system has is presented to identify patterns, which can be used to determine whether a power beam could hit a unintend- ed target and potentially cause a calamity. This has been implemented via a facts-rule network via which supplied and collected facts and a rule set is used to de- termine whether the system is operating correctly (from a …