Physical Sciences and Mathematics Commons^™

Machine Learning Based Bioinformatics Analysis Of Intron Usage Alterations And Metabolic Regulation In Adipose Browning, Hamza Umut Karakurt, Pinar Pi̇r

Turkish Journal of Electrical Engineering and Computer Sciences

Adipose tissue is the major energy depot of the body and is considered an endocrine organ. Adipose tissue involves many different cell types, first and foremost, the adipocytes. White adipose cells that store fat and brown adipocytes that take part in lipid oxidation and heat generation are the most common cell types in adipose tissue. Even though brown adipocytes which have a high number of mitochondria and high fat-burning capacity are rare in adults, they are abundant in newborns and rodents. White adipocytes can gain a temporal brown-like character with a process called browning, which can be induced with cold …