Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- 1 (11)
- 2 (9)
- Antimicrobial activity (8)
- 3 (5)
- 4-triazole (4)
-
- 4-oxadiazole (3)
- Mannich base (3)
- Michael addition (3)
- N-isocyaniminotriphenylphosphorane (3)
- Synthesis (3)
- 2-oxo-2-phenylacetaldehyde (2)
- 4-thiadiazole (2)
- Amines (2)
- Aromatic carboxylic acid (2)
- Cadmium (2)
- Cyclic voltammetry (2)
- Indole (2)
- Isocyanide (2)
- Nanoparticles (2)
- Preconcentration (2)
- Secondary amine (2)
- Silica nanoparticles (2)
- Tropolone (2)
- 1'-(Naphthalene-1 (1)
- 1-(2-pyridylazo)-2-naphthol (1)
- 1-hexyl-3-methylimidazolium hexafluorophosphate (1)
- 2'-bipyridine (1)
- 2(3H)-benzoxazolone (1)
- 2-(2-styrylcyclopent-3-enyl)benzo-[d]thiazole (1)
- 2-(2-thiazolylazo)-p-cresol (1)
Articles 1 - 30 of 75
Full-Text Articles in Physical Sciences and Mathematics
Surfactant-Sensitized Spectrophotometric Determination Of Hg(Ii) In Water Samples Using 2-(2-Thiazolylazo)- P-Cresol As Ligand And Cetylpyridinium Chloride As Cationic Surfactant, Ramazan Gürkan, Tuğba Çepken, Hali̇l İbrahi̇m Ulusoy
Surfactant-Sensitized Spectrophotometric Determination Of Hg(Ii) In Water Samples Using 2-(2-Thiazolylazo)- P-Cresol As Ligand And Cetylpyridinium Chloride As Cationic Surfactant, Ramazan Gürkan, Tuğba Çepken, Hali̇l İbrahi̇m Ulusoy
Turkish Journal of Chemistry
A new, reliable, surfactant-sensitized method is described for the spectrophotometric determination of total and dissolved inorganic mercury at trace levels. The method is based on the ternary complex formation of Hg(II) with 2-(2-thiazolylazo)-p-cresol and a cationic surfactant, cetylpyridinium chloride, at pH 9.5. The detection and quantification limits of the method with surfactant were 6 and 19 \mu g L^{-1}, while those of the method without surfactant were 22 and 67 \mu g L^{-1}, respectively. The method obeys Beer's law at up to approximately 10 mg L^{-1} Hg(II) in an aqueous surfactant medium. The relative errors and relative standard deviations of …
Polymers From Renewable Resources: Synthesis And Characterization Of Poly(2,5-Dihydro-2,5-Dimethoxy Furan), Hakan Çi̇ftçi̇, Zeki̇ Öktem, Hasan Nur Testereci̇
Polymers From Renewable Resources: Synthesis And Characterization Of Poly(2,5-Dihydro-2,5-Dimethoxy Furan), Hakan Çi̇ftçi̇, Zeki̇ Öktem, Hasan Nur Testereci̇
Turkish Journal of Chemistry
The cationic polymerization of cis, trans-2,5-dihydro-2,5-dimethoxy furan (DHMF) was studied in the presence of HClO_4, in acetonitrile. Different reaction parameters were investigated such as initiator concentration and temperature with duration. Obtained polymers were soluble in dimethylsulfoxide (DMSO) and dimethylformamide (DMF) and the M_n value was calculated as 2700 g/mol by cryoscopy. The FT-IR and ^1H-NMR results indicate that the polymerization proceeds via ring opening. Thermal properties were studied by DSC and TGA.
Four-Component Synthesis Of 1,3,4-Oxadiazole Derivatives From N-Isocyaniminotriphenylphosphorane, Aromatic Carboxylic Acids, Aromatic Bis-Aldehydes, And Secondary Amines, Ali Ramazani, Zahra Karimi, Ali Souldozi, Yavar Ahmadi
Four-Component Synthesis Of 1,3,4-Oxadiazole Derivatives From N-Isocyaniminotriphenylphosphorane, Aromatic Carboxylic Acids, Aromatic Bis-Aldehydes, And Secondary Amines, Ali Ramazani, Zahra Karimi, Ali Souldozi, Yavar Ahmadi
Turkish Journal of Chemistry
The 1:1 iminium intermediate generated by the addition of a secondary amine to aromatic bis-aldehydes (isophthalaldehyde and terphthalaldehyde) is trapped by the N-isocyaniminotriphenylphosphorane in the presence of a aromatic carboxylic acid derivative, which leads to the formation of corresponding iminophosphorane intermediate. Then disubstituted 1,3,4-oxadiazole derivatives are formed via intramolecular aza-Wittig reaction of the iminophosphorane intermediates. The reactions were completed in neutral conditions at room temperature and the corresponding disubstituted 1,3,4-oxadiazole derivatives were produced in excellent yields.
Synthesis And Chemical Transformations Of Azonine Derivatives, Ahmed A. Fadda, Elsayed M. Afsah, Samir Bondock, Mohamed M. Hammouda
Synthesis And Chemical Transformations Of Azonine Derivatives, Ahmed A. Fadda, Elsayed M. Afsah, Samir Bondock, Mohamed M. Hammouda
Turkish Journal of Chemistry
No abstract provided.
Hydrothermal Synthesis And Characterization Of Nanosized Transition Metal Chromite Spinels, Shahid Khan Durrani, Syed Zahid Hussain, Khalid Saeed, Yaqoob Khan, Mohammad Arif, Nisar Ahmed
Hydrothermal Synthesis And Characterization Of Nanosized Transition Metal Chromite Spinels, Shahid Khan Durrani, Syed Zahid Hussain, Khalid Saeed, Yaqoob Khan, Mohammad Arif, Nisar Ahmed
Turkish Journal of Chemistry
Homogeneous crystalline transition metal chromite spinels (MCr_2O_4, where M = Co, Mn, and Ni) were prepared by hydrothermal reaction of aqueous solutions containing the respective metal nitrate, chromium(III) nitrate, and sodium hydroxide in stoichiometric amounts at 180-200 °C and pH 10.5-11.5 for 11-13 h. The crystalline structure, microstructure, and thermal stability of the synthesized chromite products were analyzed by X-ray diffraction (XRD), scanning electron microscopy, thermogravimetry, and differential thermal analysis. The analysis results revealed that the CoCr_2O_4 and MnCr_2O_4 crystalline phases were thermally stable in the range of 750-800 °C. UV-visible studies showed that higher characteristic bands corresponded to the …
Ni_{55} Nanocluster: A Density Functional Theory Study Of The Binding Energy Of Nickel And Ethylene Adsorption, Nusret Duygu Yilmazer, Mehmet Ferdi̇ Fellah, Işik Önal
Ni_{55} Nanocluster: A Density Functional Theory Study Of The Binding Energy Of Nickel And Ethylene Adsorption, Nusret Duygu Yilmazer, Mehmet Ferdi̇ Fellah, Işik Önal
Turkish Journal of Chemistry
Ethylene adsorption on a Ni_{55} nanocluster was studied by means of the density functional theory (DFT)/B3LYP using the basis sets of 6-31G(d,p) and 86-411(41d)G in Gaussian 03. The Ni_{55} nanocluster was found to have a distorted icosahedral geometry, in accordance with the experimental findings. The binding energy value for the Ni_{55} nanocluster was calculated to be 3.51 eV/atom using equilibrium geometry calculations. The estimated bulk nickel binding energy was in reasonable agreement with the experimental value (4.85 versus 4.45 eV/atom). In addition, equilibrium geometry calculations were performed for ethylene adsorption on the Ni_{55} nanocluster for 2 different coordination numbers of …
Comparative Photodecolorization Of Red Dye By Anatase, Rutile (Tio_2), And Wurtzite (Zno) Using Response Surface Methodology, Shahab Khameneh Asl, Sayad Khatib Sadrnezaad, Mansour Keyanpour-Rad, Deni̇z Üner
Comparative Photodecolorization Of Red Dye By Anatase, Rutile (Tio_2), And Wurtzite (Zno) Using Response Surface Methodology, Shahab Khameneh Asl, Sayad Khatib Sadrnezaad, Mansour Keyanpour-Rad, Deni̇z Üner
Turkish Journal of Chemistry
Treatment of dye pollution containing C.I. Acid Red 14 (AR14) by a coupled photocatalytic process was studied. Titanium dioxide, in the form of anatase and rutile, and zinc oxide, were used as photocatalysts. The investigated photocatalysts were Aldrich-produced nanopowders with crystallites of a mean size of 20-30 nm and a specific surface area of about 50 m^2/g. A comparison of TiO_{2(anatase)}, TiO_{2(rutile)}, TiO_{2(a,r)}, and ZnO for the decolorization of the AR14 solution was performed. Results showed that color removal followed the decreasing order of TiO_{2(a,r)}, ZnO > TiO_{2(a,r)} > TiO_{2(a)}, ZnO > TiO_{2(r)}, ZnO >TiO_{2(a,r)} > TiO_{2(a)} > ZnO > TiO_{2(r)}. Response surface methodology (RSM) was …
Synthesis Of The Novel Benzothiazole Compounds From 7-Benzylidenebicyclo [3.2.0] Hept-2-En-6-Ones And 2-Aminobenzenethiol, Esra Findik
Turkish Journal of Chemistry
Synthesis of the 2-(2-styrylcyclopent-3-enyl)benzo-[d]thiazoles (6a-i) is reported for the first time. Reaction of 7-benzylidenebicyclo [3.2.0] hept-2-en-6-ones (3a-i) and 2-aminobenzenethiol (4) in the presence of p-TsOH as a catalyst, in ethanol under reflux, resulted in the formation of novel 2-(2-styrylcyclopent-3-enyl)benzo[d]thiazoles in high yields.
Synthesis Of \Alpha-Aminonitriles Catalyzed By Montmorillonite K10 In The Presence Of Dicationic Phosphonium Salt In Water Under Ultrasonic Effect, Çi̇ğdem Yildirim, Çi̇ğdem Yolaçan, Feray Aydoğan
Synthesis Of \Alpha-Aminonitriles Catalyzed By Montmorillonite K10 In The Presence Of Dicationic Phosphonium Salt In Water Under Ultrasonic Effect, Çi̇ğdem Yildirim, Çi̇ğdem Yolaçan, Feray Aydoğan
Turkish Journal of Chemistry
The synthesis of \alpha-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-\alpha-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.
A Dft Study On The Structural And Optical Properties And Cation Selectivities Of Some Metal-Coumarin-Crown Ether Complexes, Emi̇ne Esra Kasapbaşi, Mi̇ne Yurtsever
A Dft Study On The Structural And Optical Properties And Cation Selectivities Of Some Metal-Coumarin-Crown Ether Complexes, Emi̇ne Esra Kasapbaşi, Mi̇ne Yurtsever
Turkish Journal of Chemistry
Macrocyclic ethers are well-known molecules because of their high cation-binding capacities. They form stable complexes with alkaline and soil alkaline metals through strong oxygen bridges in solution. For enhanced optical properties, a new series of crown ethers was synthesized with a coumarin ring fused to it. The effects of the position of the coumarin ring, the type of the substituent on the coumarin ring, and the size of the crown on the optical properties of the material were studied according to the density functional theory (DFT) method at the B3LYP/6-31g(d) level of theory in the gas phase as well as …
One-Pot Synthesis Of Fully Substituted 1,3,4-Oxadiazole Derivatives From Aromatic Carboxylic Acids, Cyclobutanone And N-Isocyaniminotriphenylphosphorane, Mohsen Valizadeh Holagh, Abel Mohammadali Oglu Maharramv, Mirza Aliakbar Oglu Allahverdiyev, Ali Ramazani, Yavar Ahmadi, Ali Souldozi
One-Pot Synthesis Of Fully Substituted 1,3,4-Oxadiazole Derivatives From Aromatic Carboxylic Acids, Cyclobutanone And N-Isocyaniminotriphenylphosphorane, Mohsen Valizadeh Holagh, Abel Mohammadali Oglu Maharramv, Mirza Aliakbar Oglu Allahverdiyev, Ali Ramazani, Yavar Ahmadi, Ali Souldozi
Turkish Journal of Chemistry
Reactions of N-isocyaniminotriphenylphosphorane with cyclobutanone in the presence of aromatic (or heteroaromatic) carboxylic acids proceeded smoothly at room temperature and in neutral conditions to afford sterically congested 1-(5-aryl-1,3,4-oxadiazol-2-yl)- 1-cyclobutanol derivatives in high yields. The reaction proceeded smoothly and cleanly under mild conditions and no side reactions were observed. The structures of the products were deduced from their IR, ^1HNMR, and ^{13}CNMR spectra, and mass spectrometry.
Preparation And Antimicrobial Activity Evaluation Of Some Quinoline Derivatives Containing An Azole Nucleus, Muhammet Özyanik, Serpi̇l Demi̇rci̇, Hakan Bektaş, Nesli̇han Demi̇rbaş, Ahmet Demi̇rbaş, Şengül Alpay Karaoğlu
Preparation And Antimicrobial Activity Evaluation Of Some Quinoline Derivatives Containing An Azole Nucleus, Muhammet Özyanik, Serpi̇l Demi̇rci̇, Hakan Bektaş, Nesli̇han Demi̇rbaş, Ahmet Demi̇rbaş, Şengül Alpay Karaoğlu
Turkish Journal of Chemistry
Quinoline-2-carbohydrazide (2) obtained from quinaldic acid (1) was converted to the corresponding carbothioamide 3 and carboxamide 6 by treatment with benzyliso(thio)cyanate. The basic treatment of 3 and 6 yielded the corresponding 1,2,4-triazole derivatives 4 and 7. The synthesis of 5-(quinolin-2-yl)-1,3,4- oxadiazol-2-thiol (9) was performed from the reaction of 1 with CS_2 in basic media. The Mannich reaction of compounds 4, 7, and 9 resulted in the formation of aminoalkylated derivatives 5a-c, 8, and 10a,b. The condensation of 1 with thiosemicarbazide, carbohydrazide, or thiocarbohydrazide gave the corresponding 1,2,4-triazole derivatives (11-13). The treatment of 4-amino-5-(quinolin-2-yl)- 4H-1,2,4-triazole-3-thiol (13) with 4-chlorophenacyl bromide caused the …
Determination Of Cadmium In High Salt Content Matrices By Flow Injection Cold Vapor Atomic Absorption Spectrometry, Orkun Alp, Hakan Demi̇röz, Osman Yavuz Ataman, Nusret Ertaş
Determination Of Cadmium In High Salt Content Matrices By Flow Injection Cold Vapor Atomic Absorption Spectrometry, Orkun Alp, Hakan Demi̇röz, Osman Yavuz Ataman, Nusret Ertaş
Turkish Journal of Chemistry
Flow injection cold vapor atomic absorption spectrometry (FI-CVAAS) was used for determination of cadmium in high salt matrices such as dialysis concentrates and textile leach solutions. The parameters such as acidity, concentration of reducing agent, reaction coil length, and carrier gas flow rate were investigated to obtain the best sensitivity. No significant background signal was observed even at high salt concentrations. Under the optimized conditions the limit of detection value (3s_b m^{-1}, where s_b is the standard deviation of the blank signals and m is the slope of the calibration graph) was found to be 0.05 ng mL^{-1} for an …
Synthesis Of Some New Urea And Thiourea Derivatives And Evaluation Of Their Antimicrobial Activities, Yildiz Gülkok, Tuba Bi̇çer, Fatma Kaynak Onurdağ, Selda Özgen, Mustafa Fethi̇ Şahi̇n, Deni̇z Songül Doğruer
Synthesis Of Some New Urea And Thiourea Derivatives And Evaluation Of Their Antimicrobial Activities, Yildiz Gülkok, Tuba Bi̇çer, Fatma Kaynak Onurdağ, Selda Özgen, Mustafa Fethi̇ Şahi̇n, Deni̇z Songül Doğruer
Turkish Journal of Chemistry
In the present study, 18 new compounds were synthesized, 9 of which were urea (9a-e, 10a-d) while the others were thiourea (11a-e, 12a-d) derivatives. These derivatives were prepared by the reaction of 6-amino-5-nonsubstituted/chloro-3-methyl-2(3H)- benzoxazolones used as key intermediates with the appropriate isocyanates and isothiocyanates. The chemical structures of new compounds were confirmed by ^1H-NMR, mass, and elemental analysis. The synthesized compounds were screened for their antibacterial and antifungal activities against some pathogenic strains. Compounds 9a, 9b, 9e, 10a, and 10c, urea derivatives, and compounds 12a and 12d, thiourea derivatives, exhibited a relatively good inhibitory profile against E. coli, with a …
Synthesis And Evaluation Of Enzyme Inhibitory Potential Of Some Derivatives Of Scopolamine, Durre Shahwar, Muhammad Asam Raza, Tania Khan
Synthesis And Evaluation Of Enzyme Inhibitory Potential Of Some Derivatives Of Scopolamine, Durre Shahwar, Muhammad Asam Raza, Tania Khan
Turkish Journal of Chemistry
This study was designed to synthesize and evaluate derivatives of scopolamine (1) as acetylcholine esterase and protease inhibitors. Scopolamine (1) was extracted from the aerial parts of Datura innoxia through bioassay guided fractionation. Five different derivatives of scopolamine (1) were synthesized, and identified through spectroscopic studies. Their acetylcholine esterase (AChE) and trypsin inhibitory potentials were determined through standard protocols and evaluated from the perspective of structure-activity relationship. The synthesized scopolamine derivatives (2-6) showed remarkable AChE inhibitory activity, except for scopoline (6). The results showed higher enzyme inhibition potential of the synthesized compounds (2-5) as compared to scopolamine (1). Maximum inhibition …
Simultaneous Determination Of Cr(Iii) And Cr(Vi) Using Differential Pulse Polarography And Application To Gerede River, Olcay Şendi̇l, Nabeel Mohammed, Güler Somer
Simultaneous Determination Of Cr(Iii) And Cr(Vi) Using Differential Pulse Polarography And Application To Gerede River, Olcay Şendi̇l, Nabeel Mohammed, Güler Somer
Turkish Journal of Chemistry
Determination of Cr(III) in the presence of Cr(VI) from one polarogram is not easy. No such procedure was found in the literature. In polarographic studies Cr(III) had a peak only in acidic medium, while Cr(VI) had either 1 or 2 peaks in both acidic and basic solutions. In solutions that contain these 2 ions, the peak obtained in acidic medium for Cr(III) will be the sum of both ions. Thus, Cr(III) cannot be determined directly from one polarogram. In this work, a new and simple polarographic method is established for the determination of Cr(III) and Cr(VI) by using only one …
^{99m}Tc Labeled Levofloxacin As An Infection Imaging Agent: A Novel Method For Labeling Levofloxacin Using Cysteine\Cdot Hcl As Co-Ligand And In Vivo Study, Syed Ali Raza Naqvi, Malik Muhammad Ishfaq, Zulfiqar Ali Khan, Saeed Ahmad Nagra, Iftikhar Hussain Bukhari, Abdullah Ijaz Hussain, Nasir Mahmood, Sohail Anjum Shahzad, Asma Haque, Tanveer Hussain Bokhari
^{99m}Tc Labeled Levofloxacin As An Infection Imaging Agent: A Novel Method For Labeling Levofloxacin Using Cysteine\Cdot Hcl As Co-Ligand And In Vivo Study, Syed Ali Raza Naqvi, Malik Muhammad Ishfaq, Zulfiqar Ali Khan, Saeed Ahmad Nagra, Iftikhar Hussain Bukhari, Abdullah Ijaz Hussain, Nasir Mahmood, Sohail Anjum Shahzad, Asma Haque, Tanveer Hussain Bokhari
Turkish Journal of Chemistry
Levofloxacin was labeled with ^{99m}Tc using cysteine\cdot HCl as co-ligand and SnCl_2.2H_2O as reducing agent. The influence of various parameters such as amount of cysteine\cdot HCl, reducing agent, pH value, and reaction time on labeling process was studied. After optimizing the conditions the labeling was performed at pH 5 using 1 mg of levofloxacin, 500 \mu g of cysteine\cdot HCl, 50 \mu g of SnCl_2.2H_2O, and 15 min reaction time. The radiochemical purity was determined with the help of instant thin layer chromatography (ITLC) and reverse phase high performance liquid chromatography (RP-HPLC) which was more than 95% and was stable …
Antimicrobial Properties And Dna Interactions Studies Of 3-Hetarylazoquinoline-2,4-Diol Compounds, Fatma Öztürk, Leyla Açik, İzzet Şener, Fi̇kret Karci, Emi̇ne Kiliç
Antimicrobial Properties And Dna Interactions Studies Of 3-Hetarylazoquinoline-2,4-Diol Compounds, Fatma Öztürk, Leyla Açik, İzzet Şener, Fi̇kret Karci, Emi̇ne Kiliç
Turkish Journal of Chemistry
The purpose of the present study was to evaluate the antimicrobial effects of 3-hetarylazoquinoline-2,4-diols (19), having substituted or unsubstituted thiazole, benzothiazole, benzimidazole, triazole, isoxazole, and thiadiazole moieties at the 3-position, on bacterial and yeast strains. In addition, compounds and DNA interaction with pUC18 plasmid DNA were studied. The biological effects of these molecules were compared with potential antibiotics ampicillin,~chloramfenicol (for bacteria), and ketoconozole (for yeast). According to the results, all compounds except 8 have mild to moderate activity against some of the bacterial strains tested, and none of the compounds have activity against the fungi C. tropicalis and C. albicans. …
Influence Of Reaction Parameters On The Synthesis Of Surfactant-Assisted Tin Oxide Nanoparticles, Muhammad Akhyar Farrukh, Prisca Tan, Rohana Adnan
Influence Of Reaction Parameters On The Synthesis Of Surfactant-Assisted Tin Oxide Nanoparticles, Muhammad Akhyar Farrukh, Prisca Tan, Rohana Adnan
Turkish Journal of Chemistry
Tin oxide nanoparticles were synthesized via hydrothermal method using a non-ionic surfactant, oleyl amine (OLM), in the presence of urea. The reactions were carried out at different calcination temperatures and varying concentrations of surfactant and urea. The effect of these reaction parameters on the particles' size, distribution, surface area, and the average pore diameter were investigated using X-ray diffraction analysis, transmission electron microscopy, scanning electron microscopy, energy dispersive X-ray analysis, thermogravimetric analysis, Brunauer-Emmett-Teller method, and Fourier transform infrared spectroscopy. Larger tin oxide nanoparticles were obtained with higher concentrations of urea. At the optimum experimental conditions, tin oxide nanoparticles with mean …
Novel Biologically Active Glycosides From The Aerial Parts Of Cephalaria Gazipashensis, Nazli Böke Sarikahya, Süheyla Kirmizigül
Novel Biologically Active Glycosides From The Aerial Parts Of Cephalaria Gazipashensis, Nazli Böke Sarikahya, Süheyla Kirmizigül
Turkish Journal of Chemistry
Two new triterpene glycosides, 3-O-\beta-D-glucopyranosyl- (1\to 4)-\beta-D-xylopyranosyl-(1\to 3)-\alpha-L-rhamnopyranosyl- (1\to 3)-\alpha-L-arabinopyranosyl olean-12-ene 28-O-\beta -D- glucopyranosyl-(1\to 6)-\beta-D-glucopyranosyl ester (gazipashoside A, 1) and 3-O-\beta-D-glucopyranosyl-(1\to 4)-\beta-D-xylopyranosyl- (1\to 3)-\alpha-L-rhamnopyranosyl-(1\to 2)-\alpha-L-arabinopyranosyl hederagenin 28-O-\beta -D-glucopyranosyl-(1\to 6)-\beta-D-glucopyranosyl ester (gazipashoside B, 2), were isolated together with 11 known compounds including 7 triterpene, 1 flavonoid, and 3 iridoidal metabolites from the aerial parts of Cephalaria gazipashensis (Dipsacaceae). The structures of all compounds were elucidated by extensive evaluation of the spectroscopic data (1D- and 2D- NMR, HRESI-MS), as well as chemical examinations. The antimicrobial effects of all pure compounds were tested against gram-positive and gram-negative bacteria. The results indicated that the …
Synthesis, Anti-Inflammatory, Antiplatelet And In Silico Evaluations Of (E)-3-(3-(2,3-Dihydro-3-Methyl-2-Oxo- 3h-Benzoxazole-6-Yl)-1-Phenyl-1h-Pyrazole- 4-Yl)Acrylamides, Sultan Baytaş, Ni̇lüfer Nermi̇n Turan Dural, Yeşi̇m Özkan, Hasan Bolkan Şi̇mşek, Türki̇z Gürsel, Serdar Ünlü
Synthesis, Anti-Inflammatory, Antiplatelet And In Silico Evaluations Of (E)-3-(3-(2,3-Dihydro-3-Methyl-2-Oxo- 3h-Benzoxazole-6-Yl)-1-Phenyl-1h-Pyrazole- 4-Yl)Acrylamides, Sultan Baytaş, Ni̇lüfer Nermi̇n Turan Dural, Yeşi̇m Özkan, Hasan Bolkan Şi̇mşek, Türki̇z Gürsel, Serdar Ünlü
Turkish Journal of Chemistry
A series of (E)-3-(3-(2,3-dihydro-3-methyl-2-oxo-3H-benzoxazole- 6-yl)-1-phenyl-1H-pyrazole-4-yl)acry- lamides (7a--k) were synthesized and evaluated for their in vitro inhibitory activities on COX-1 and COX-2 isoforms using a human whole blood assay as well as their antiplatelet profile against human platelet aggregation using arachidonic acid as agonists. Among the synthesized derivatives 7a--k, especially compound 7g exhibited dual anti-inflammatory and antiplatelet activity with selective COX-2 inhibition.
Evaluation Of Thermodynamic Parameters Of Cadmium Adsorption On Sand From Temkin Adsorption Isotherm, Abdul Sattar Ali Khan
Evaluation Of Thermodynamic Parameters Of Cadmium Adsorption On Sand From Temkin Adsorption Isotherm, Abdul Sattar Ali Khan
Turkish Journal of Chemistry
Thermodynamic parameters provide clues for finding the spontaneity of a given process at a given temperature. In the present work, the Temkin adsorption model was applied for evaluation of the thermodynamic parameters of cadmium adsorption studied on sand. The lateral interaction energy parameter was found to be unity, which showed that the heat of adsorption is directly proportional to the fraction of free adsorption sites. The values of \Delta H° and \Delta S° were --4.8 kJ mol^{-1} and 42 J mol^{-1} K^{-1}, respectively. The value of \Delta G° was negative, indicating the spontaneity of cadmium adsorption on sand.
Copolymerization Of N-Vinyl Pyrrolidone With Methyl Methacrylate By Ti(Iii)-Dmg Redox Initiator, Ajithkumar Manayan Parambil, Yashoda Malagar Puttaiahgowda, Prasannakumar Shankarappa
Copolymerization Of N-Vinyl Pyrrolidone With Methyl Methacrylate By Ti(Iii)-Dmg Redox Initiator, Ajithkumar Manayan Parambil, Yashoda Malagar Puttaiahgowda, Prasannakumar Shankarappa
Turkish Journal of Chemistry
Redox copolymerization of N-vinyl-2-pyrrolidone (NVP) with methyl methacrylate (MMA) was carried out using titanium(III)-- dimethylglyoxime [Ti(III)-DMG] redox initiator in aqueous sulfuric acid-alcohol media. The resulting copolymer was characterized by FTIR, ^1H-NMR, and ^{13}C-NMR spectroscopic methods and elemental analysis. Thermal properties of the copolymer were determined by differential scanning calorimetric technique and thermogravimetric analysis. The reactivity ratios of the monomers were computed by Fineman-Ross, Kelen-Tudos, and extended Kelen-Tudos methods at lower conversion. The reactivity ratios obtained r_1 (MMA) 1.69 and r_2 (NVP) 0.03 showed richer content of MMA than NVP in the copolymer having extreme ideal behavior. The distribution of monomer …
Competitive Hydrogen Bonding In Aspirin-Aspirin And Aspirin-Leucine Interactions, Zeynep Yurtsever, Burak Erman, İsmai̇l Ersi̇n Yurtsever
Competitive Hydrogen Bonding In Aspirin-Aspirin And Aspirin-Leucine Interactions, Zeynep Yurtsever, Burak Erman, İsmai̇l Ersi̇n Yurtsever
Turkish Journal of Chemistry
Aspirin-aspirin and aspirin-leucine interactions are studied by the density functional theory (DFT) and high level ab initio calculations with second order Moller-Plesset perturbation theory (MP2). The rotational isomers of aspirin are identified by their relative stability both in gaseous phase and in water using the polarizable continuum method (PCM). Local minima of aspirin monomers in water are found to be all highly populated compared to the gas phase behavior. Homodimers of aspirin form hydrogen bonds with bond energies of 10 kcal/mol. Weak hydrogen bonds utilizing phenyl and methyl groups are also found. The interaction between aspirin and leucine is stronger …
Silica Nanoparticles As A High Efficient Catalyst For The One-Pot Synthesis Of 3-Oxo-3-Phenylpropanamid Derivatives From Isocyanides, Phenylacetaldehyde And Secondary Amines, Ali Ramazani, Kourosh Dastanra, Fatemeh Zeinali Nasrabadi, Zahra Karimi, Morteza Rouhani, Mehdi Hosseini
Silica Nanoparticles As A High Efficient Catalyst For The One-Pot Synthesis Of 3-Oxo-3-Phenylpropanamid Derivatives From Isocyanides, Phenylacetaldehyde And Secondary Amines, Ali Ramazani, Kourosh Dastanra, Fatemeh Zeinali Nasrabadi, Zahra Karimi, Morteza Rouhani, Mehdi Hosseini
Turkish Journal of Chemistry
Reaction of an isocyanide with an iminium ion intermediate, formed by reaction between 2-oxo-2-phenylacetaldehyde and a secondary amine in the presence of silica nanoparticles, proceeds smoothly at room temperature to afford ketoamide derivatives in high yields.
Transmission Ft-Ir Spectroscopic Analysis Of Human Kidney Stones In The Hyderabad Region Of Pakistan, Muhammad Hussan Khaskheli, Syed Tufail Hussain Sherazi, Huma Mazhar Ujan, Sarfaraz Ahmed Mahesar
Transmission Ft-Ir Spectroscopic Analysis Of Human Kidney Stones In The Hyderabad Region Of Pakistan, Muhammad Hussan Khaskheli, Syed Tufail Hussain Sherazi, Huma Mazhar Ujan, Sarfaraz Ahmed Mahesar
Turkish Journal of Chemistry
The purpose of the present study was to investigate the composition of kidney stones removed from human patients. Seventeen samples were collected after surgery (5 females and 12 males; age range 2 to 60 years). The samples were analyzed for composition by transmission Fourier transform infrared (FT-IR) spectroscopy. The 17 analyzed samples of kidney stones comprised 29.4% calcium oxalate, 29.4% uric acid, 29.4% calcium oxalate (CaOx)-uric acid, 5.9% phosphate, and 5.9% calcium oxalate-phosphate stones. The results of the study indicated that transmission FT-IR spectroscopy could be used as an environmentally friendly technique for rapid screening of kidney stones.
Synthesis, Characterization, And Antioxidant Activities Of New Trisubstituted Triazoles, Kemal Sancak, Yasemi̇n Ünver, Di̇lek Ünlüer, Esra Düğdü, Gülcan Kör, Fati̇h Çeli̇k, Emrah Bi̇ri̇nci̇
Synthesis, Characterization, And Antioxidant Activities Of New Trisubstituted Triazoles, Kemal Sancak, Yasemi̇n Ünver, Di̇lek Ünlüer, Esra Düğdü, Gülcan Kör, Fati̇h Çeli̇k, Emrah Bi̇ri̇nci̇
Turkish Journal of Chemistry
A series of new 4-(3,4dimethoxyphenethyl)-3,5-akyl/aryl-4H- 1,2,4-triazoles (3a-g) were obtained by reaction of ethyl N'-(alkylidene/arylidene)hydrazonate (1) and 2-(3,4-dimethoxy phenyl)ethanamine (2). Compounds 4d, e, and g were synthesized from the reaction of corresponding compounds 3d, e, and g with BBr_3, respectively. The 10 new compounds synthesized were characterized by elemental analyses, IR, ^1H-NMR, and ^{13}C-NMR spectral data. The structure of compound 3g was inferred through IR, ^1H-, ^{13}C-NMR, elemental analyses, and X-ray spectral techniques. In addition, the newly synthesized chemicals were screened for their antioxidant properties. Among the chemicals tested, 4d, e, and g exhibited the highest degree of antioxidant activity.
Three-Component Passerini-Smiles Coupling Reaction Of Aldehydes And Isocyanides With Tropolone Catalyzed By Silica Nanoparticles, Abdolhossain Massoudi, Issa Amini, Ali Ramazani, Fatemeh Zeinali Nasrabadi
Three-Component Passerini-Smiles Coupling Reaction Of Aldehydes And Isocyanides With Tropolone Catalyzed By Silica Nanoparticles, Abdolhossain Massoudi, Issa Amini, Ali Ramazani, Fatemeh Zeinali Nasrabadi
Turkish Journal of Chemistry
The use of Smiles rearrangement in Passerini-type couplings with tropolone allows very straightforward multicomponent formation of \alpha-aryloxy amide derivatives. The 3-component addition of isocyanide to tropolone (2-hydroxy-2,4,6-cycloheptatrien-1-one) and aldehyde in the presence of silica nanoparticles (silica NP, ca. 70 nm) proceeds easily in methanol to form the title compounds in a new Passerini-Smiles-type reaction.
Microwave-Assisted Synthesis, Spectroscopy, And Crystal Structures Of [(H_2-(4,4'-Bipy)]^{2+} [Cr_2o_7]^{2-} And One-Dimensional Polymeric {[Mn(4,4'-Bipy)(Cr_2o_7)(H_2o)_2]\}_N Compounds, Hirihattaya Phetmung, Munee Wateh, Chaveng Pakawatchai
Microwave-Assisted Synthesis, Spectroscopy, And Crystal Structures Of [(H_2-(4,4'-Bipy)]^{2+} [Cr_2o_7]^{2-} And One-Dimensional Polymeric {[Mn(4,4'-Bipy)(Cr_2o_7)(H_2o)_2]\}_N Compounds, Hirihattaya Phetmung, Munee Wateh, Chaveng Pakawatchai
Turkish Journal of Chemistry
A compound (1), [H_2-(4,4'-bipy)]^{2+}[(Cr_2O_7)]^{2-} and a metal organic-inorganic coordination framework (2), [Mn(4,4'-bipy)(Cr_2O_77)(H_2O)_2] (4,4'-bipy=4,4' -bipyridine) were successfully synthesized by microwave method. Their characterization was performed by single crystal X-ray crystallography and FT-IR spectroscopy. The crystal structure of 1 revealed a diprotonated 4,4'-bipyridium dichromate compound while compound 2 is an onedimensional (1D) polymer in which (Cr_2O_7)^{2-} acts as a bridging ligand supporting the formation of infinite {[Mn(4,4'-bipy)(Cr_2O_7)(H_2O)_2]}_n polymeric chains. The geometry of the 4,4'-bipy ring in 1 is typical coplanar, but twists in 2. In the free molecule 1, dichromate ligand adopts an eclipsed conformation, but adopts a staggered conformation in complex. …
Design, Synthesis, And Biological Evaluation Of Indole-Based 1,4-Disubstituted Piperazines As Cytotoxic Agents, Meri̇ç Köksal Akkoç, Mi̇ne Yarim Yüksel, İrem Durmaz, Rengül Çeti̇n Atalay
Design, Synthesis, And Biological Evaluation Of Indole-Based 1,4-Disubstituted Piperazines As Cytotoxic Agents, Meri̇ç Köksal Akkoç, Mi̇ne Yarim Yüksel, İrem Durmaz, Rengül Çeti̇n Atalay
Turkish Journal of Chemistry
A series of 3-[(4-substitutedpiperazin-1-yl)methyl]-1H-indole derivatives were synthesized, and their structures were confirmed by spectral analysis. All the compounds were tested for their cytotoxic activity in vitro against 3 human tumor cell lines: human liver (HUH7), breast (MCF7), and colon (HCT116). Among the designed derivatives, most of the compounds showed significant cytotoxicity against liver and colon cancer cell lines with lower IC_{50} concentrations than the standard drug 5-fluorouracil. Compound 3s, with 3,4-dichlorophenyl substituent on the piperazine ring, was the most active in suppressing the growth of all screened cancer cells.