Physical Sciences and Mathematics | Open Access Articles

Advances In The Chemistry Of Pyrazolopyrazoles, Rizk Elsyad Khidre, Hanan Ahmed Mohamed, Bakr Fathy Abdelwahab

Turkish Journal of Chemistry

Published data on the methods of preparation of pyrazolopyrazoles are summarized and described systematically. The title compounds are subdivided according to the position of fusion between the 2 pyrazole rings.

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Fabrication Of Layer-By-Layer Deposited Films Containing Carbon Nanotubes And Poly(Malachite Green) As A Sensor For Simultaneous Determination Of Ascorbic Acid, Epinephrine, And Uric Acid, Jahan Bakhsh Raoof, Reza Ojani, Mehdi Baghayeri

Turkish Journal of Chemistry

A simple approach to constructing a double-layer voltammetric sensor is described. The poly(malachite green) (PMG) and multiwalled carbon nanotubes (MWCNTs) were coimmobilized at the surface of the glassy carbon electrode (GCE) for fabrication of PMG/MWCNT/GCE. The modified electrode was characterized by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), differential pulse voltammetry (DPV), and chronoamperometric techniques. Using DPV, the obtained catalytic peak current was linearly dependent on the ascorbic acid (AA), epinephrine (EP), and uric acid (UA) concentrations in the ranges of 0.4-100.0, 0.1-100.0, and 0.3-90.0 \muM, respectively. The resultant detection limits for AA, EP, and UA were 0.23, 0.0820, and …

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Electrochemical Properties Of 1,3-Disubstituted Methyl Methoxy Phenyl-5-Phenylformazans And Comparison With Spectral Properties, Habi̇be Tezcan, Güler Ekmekci̇, Mehmet Levent Aksu

Turkish Journal of Chemistry

In this study, electrochemical behaviors of formazans were investigated. The compounds contained CH_3 and OCH_3 groups at the o-, m-, and p-positions of the 1-phenyl ring and an OCH_3 group at the p-position of the 3-phenyl ring. Their electrochemical behaviors, such as the number of electrons transferred, diffusion coefficients, and heterogeneous rate constants, were studied by cyclic voltammetry, ultramicrodisk electrode, and chronoamperometry. Possible mechanisms were proposed based upon the data obtained. There was a correlation between the absorption and electrochemical properties. A linear correlation was obtained between \lambda_{\max} and E_{red2} and Hammett substituent coefficients with E_{red2} and k_s values.

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A New Method For Calculating The Vibration-Rotation-Tunneling Spectra Of Molecular Clusters And Its Application To The Water Dimer, Mahi̇r Erteki̇n Ocak

Turkish Journal of Chemistry

A new method is developed for calculating the vibration-rotation-tunneling spectra of molecular clusters consisting of rigid monomers. The method is based on generation of optimized bases for each monomer. First, a sequential symmetry adaptation procedure is developed for relating the symmetries of monomer basis functions with the symmetries of the eigenstates of the cluster. Then this symmetry adaptation procedure is used in the generation of optimized bases and combining them for finding the eigenstates. Symmetry adaptation problems related to the generation of optimized bases are identified and solutions are suggested. The method is applied to the water dimer by using …

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Mechanochemical Modification Method Used In The Development Of New Composite Materials Based On Epoxy Binder And Natural Minerals, Umida Ziyamukhamedova, Dilshod Djumabaev, Botirali Shaymardanov

Turkish Journal of Chemistry

This article highlights the results of a mechanochemical modification method of epoxy composite materials and coatings on their base. It proves the mechanochemical activated components of composition to be the most acceptable for structuring when producing composite materials. It also states the increase of mechanical properties of epoxy heterocomposite coatings with mechanically activated particles by 25%-40%.

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Synthesis And Characterization Of Ni(Ii) And Cu(Ii) Complexes Derived From Novel Phenolic Mannich Bases, Nurgün Büyükkidan, Sali̇h Özer

Turkish Journal of Chemistry

The novel phenolic Mannich bases 2,2'-(2-hydroxy-4,5- dimethylbenzylazanediyl)diethanol (1) and 2-((2-(4-(2-hydroxy-4,5- dimethylbenzyl)piperazin-1-yl)ethylamino)methyl)-4,5-dimethylphenol (2) have been synthesized in good yield by using a microwave-induced technique from 3,4-dimethylphenol and corresponding amines in the presence of formaldehyde. Metal complexes of 1 and 2 for Ni(II) (3 and 5) and for Cu(II) (4 and 6) have also been prepared and all compounds have been characterized by elemental and spectral analyses. Thermal, magnetic, and electronic studies have also been reported for metal complexes. Electronic spectra and magnetic susceptibility measurements suggested tetrahedral geometry for Ni(II) (3), square planar geometry for Cu(II) (4) complexes of 1, and octahedral …

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Molecular Docking And Qsar Study On Imidazole Derivatives As 14 /Alpha -Demethylase Inhibitors, Asghar Davood, Maryam Iman

Turkish Journal of Chemistry

14\alpha-Demethylase (CYP51) inhibitors have been widely used in the treatment of fungal infections. In this study, a series of imidazole derivatives with CYP51 inhibitory activity were subjected to a molecular docking study followed by quantitative structure-activity relationship (QSAR) analyses in search of the ideal physicochemical characteristics of potential CYP51 inhibitors. Desired imidazoles were built using the HyperChem program, and conformational studies were performed through a semiempirical method followed by the PM3 method. Docking study was performed using the AutoDock program on all of the compounds. Different QSAR descriptors were calculated using DRAGON, AutoDock, and HyperChem. Multilinear regression was used as …

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Enaminonitriles In Heterocyclic Synthesis: Synthesis And Biological Evaluation Of Novel Indeno[2,1-B]Thiophene Derivatives, Ahmed A. Fadda, Abd El Galil M. Khalil, Eman H. Tawfik

Turkish Journal of Chemistry

No abstract provided.

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Synthesis, Characterization, And Swelling Behaviors Of A Ph-Responsive Cmc-G-Poly(Aa-Co-Amps) Superabsorbent Hydrogel, Yizhe Wang, Xiaoning Shi, Wenbo Wang, Aiqin Wang

Turkish Journal of Chemistry

New superabsorbent hydrogels were synthesized through free radical graft copolymerization of partially neutralized acrylic acid (AA) and 2-acrylamido-2-methylpropanesulfonic acid (AMPS) onto carboxymethyl cellulose (CMC) backbones. The structure and morphology of the synthesized superabsorbent hydrogels were characterized by Fourier transform infrared spectroscopy and scanning electron microscope. The effect of the molar ratio of AMPS to AA, the APS concentration, and the CMC content on swelling ratio was optimized. The swelling properties in various pH solutions and saline solutions as well as the swelling kinetics were also evaluated. Results showed that the introduction of AMPS enhanced the swelling capacity, swelling rate, and …

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Synthesis, Characterization, And Antimicrobial Activity Of Some New Phosphorus Macrocyclic Compounds Containing Pyrazole Rings, Tarik El-Sayed Ali, Salah Abdel-Aziz Abdel-Ghaffar, Kamilia Mohamed El-Mahdy, Somaia Mohamed Abdel-Karim

Turkish Journal of Chemistry

A simple synthetic method is reported for the preparation of some new phosphorus macrocycles in which the pyrazole rings are appended to a phosphorus atom. The methodology is based on the cyclocondensation reaction of bis(4-formylpyrazolyl) phosphine oxide(1a, 1b) with nitrogen nucleophiles that contain active terminal amino groups. The antimicrobial activities of the synthesized compounds were assayed.

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Removal Of Cr(Iii) And Cu(Ii) Using Oly(2-Chloroaniline)/Polyvinylidenefluoride Composite Cation-Exchange Membranes By Donnan Dialysis, Esengül Kir, Sabri̇ye Perçi̇n Özkorucuklu, Tuğba Sardohan Köseoğlu, Esi̇n Karamizrak

Turkish Journal of Chemistry

P2ClAn/PVDF composite membranes were prepared utilizing cation-exchange groups in the PVDF (polyvinylidenefluoride) membrane matrix by casting method. The poly(2-chloroaniline) (P2ClAn) was chemically synthesized with different dopant anions such as o-aminobenzene sulfonic acid (ABS) and sodium dodecyl sulfate (SDS). P2ClAn/PVDF membranes were extensively characterized for their surface morphology, thickness, ion-exchange capacity, SEM, AFM, and FTIR-ATR measurements. The SEM, AFM and FTIR-ATR pictures, comparing the original PVDF membrane support sheet to P2ClAn/PVDF composite membranes, indicate that the morphologies of the membranes are different. The membrane potential measurements were performed in various electrolyte solutions in order to observe the selectivity and stability of …

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Antimicrobial Activity And Chemical Composition Of The Essential Oils Of Mosses (Hylocomium Splendens (Hedw.) Schimp. And Leucodon Sciuroides (Hedw.) Schwägr.) Growing In Turkey, Tayyi̇be Beyza Cansu, Büşra Yayli, Turan Özdemi̇r, Nevzat Batan, Şengül Alpay Karaoğlu, Nuretti̇n Yayli

Turkish Journal of Chemistry

In the present work, the volatiles of mosses [Hylocomium splendens (Hedw.) Schimp. (Hylocomiaceae) and Leucodon sciuroides (Hedw.) Schwägr. (Leucodontaceae)] have been investigated by GC-FID and GC/MS. Fifty-eight compounds in the oil of H. splendens, representing 75.4%, and 41 compounds in the oil of L. sciuroides, representing 87.6%, were identified. The major components were found to be \beta-pinene (11.6%) and \alpha-pinene (8.9%) in the oil of H. splendens, and nonanal (26.8%) and heptanal (13.7%) in the oil of L. sciuroides. The essential oil of H. splendens was rich in monoterpenes (30.8%), and aldehydes (49.9%) were the major constituents in the oil …

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Synthesis And Characterization Of Thermally Stable Camphor-Based Polyimide--Clay Nanocomposites, Murat Yi̇ği̇t, Turgay Seçki̇n, Beyhan Yi̇ği̇t, Süleyman Köytepe

Turkish Journal of Chemistry

A new monomer was prepared from (1R,3S)-(+)-camphoric acid. Novel polyimide and polyimide--clay hybrid composites were developed from one-pot condensation reactions of this monomer and pyromellitic dianhyride. Polyimide-montmorillonite nanocomposites were prepared from solution of polyimide and with different weight percentages (1, 5, 10 wt %) of organo-modified montmorillonite (OM-MMT) using N-methyl-2-pyrrolidone (NMP) as aprotic solvent. The reactive organoclay was formed by using hexadecylpyridinium chloride as a swelling agent for silicate layers of montmorillonite. The polyimide--clay composites films (PI--MMT) were characterized by Fourier transform infrared spectroscopy, scanning electron microscopy (SEM), and X-ray diffraction (XRD). All composites were subjected to differential scanning calorimetry …

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Ionic Liquid Mediated Synthesis, Reactions, And Insecticidal Activity Of 1-[(1h-Benzoimidazol-2-Yl)Amino]Spiro[Azetidine-4,4'-[4'H]Chroman]-2-Ones, Dr Kanti Sharma, Renuka Jain

Turkish Journal of Chemistry

Ionic liquid mediated synthesis of novel heterocyclic compounds 1-[(1H-benzoimidazol-2-yl)amino]-2'-phenylspiro[azetidine- 4,4'-[4'H]chroman]-2-ones (3) and 1-[(1H-benzoimidazol-2-yl)amino]- 3-chloro-2'-phenylspiro[aze tidine-4,4'-[4'H] chroman]-2-ones (4) was accomplished by condensing substituted 2-hydrazino benzimidazole (1), flavanone (2), and acetyl chloride/chloroacetyl chloride in ionic liquid, [bmim]PF_6 with or without using catalyst in excellent yield (90%--95%). Further, compounds 3 and 4 were acylated with trifluoroacetic anhydride to give N-acylated products (5 and 10); 3 when treated with HCHO and (C_2H_5)_2NH gave Mannich bases (6) and with aldehydes afforded 3-arylidene-2-azetidinone (7). Compounds 4 underwent nucleophilic substitution with (i) KI (Finkelstein reaction) and (ii) phenols to give the corresponding iodo and phenoxy derivatives (8 …

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Synthesis And Cytotoxic Activity Of Some 2-(2,3-Dioxo-2,3-Dihydro-1h-Indol-1-Yl)Acetamide Derivatives, Özlem Akgül, Ayşe Hande Tari̇koğullari, Fadi̇me Aydin Köse, Petek Ballar Kirmizibayrak, Mehmet Varol Pabuççuoğlu

Turkish Journal of Chemistry

Isatin, 1H-indoline-2,3-dione, an endogenous compound, is also a synthetically versatile molecule that possesses a diversity of biological activities including anticonvulsant, antibacterial, antifungal, antiviral, anticancer, and cytotoxic properties. Based on the promising cytotoxic activity studies on N-substituted isatin derivatives, a series of 18 derivatives of 2-(2,3-dioxo-2,3-dihydro- 1H-indol-1-yl)-N-phenylacetamide were designed, synthesized, and characterized according to their analytical and spectral data. All of the compounds were evaluated for their cytotoxic activity against MCF7, A549, HeLa, and HEK293 cell lines by real time cell analyzer. Etoposide was used as a standard compound. Briefly, ortho substitutions gave better results compared to meta and para substitutions …

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Synthesis And Antimicrobial Investigation Of Some 5h-Pyridazino[4,5-B]Indoles, İlker Avan, Alaetti̇n Güven, Kiymet Güven

Turkish Journal of Chemistry

Synthesis and in vitro antimicrobial activities are reported for a series of 1,3,5-substituted 4-oxo-3,4-dihydro-5H-pyridazino[4,5-b]indole derivatives. Corresponding pyridazino[4,5-b]indoles were prepared from ethyl 3-formyl-1H-indole-2-carboxylate precursors and the functional group in question was installed with hydrazine and its derivatives. The purity and primary structures of pyridazino[4,5-b]indole were confirmed by IR, ^1 H NMR, and ^{13}C NMR spectroscopy and elemental analyses. All of the indoles were tested for in vitro antimicrobial activity against 8 isolates of bacteria and a fungus including Staphylococcus aureus NRRL B-767, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Proteus vulgaris NRRL-B123, Salmonella typhimurium NRRL B-4420, Bacillus subtilis NRRL 744, …

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Synthesis And Evaluation Of Acetylcholineesterase Inhibitory Potential And Antioxidant Activity Of Benzothiazine Derivatives, Durre Shahwar, Uzma Sana, Naeem Ahmad

Turkish Journal of Chemistry

The aim of the present study was to synthesize and characterize benzothiazine derivatives prepared by using 2-aminothiophenol and saccharine and in vitro screen their enzyme inhibition and antioxidant potential. Nine different derivatives were prepared and their structures were confirmed by spectral studies (EIMS, ^1 H and ^{13}C NMR). Enzyme inhibition potential of the synthesized compounds was evaluated by Ellman's method, while antioxidant activity was determined by DPPH and FRAP assays. All the derivatives showed remarkable activity against acetylcholine esterase with IC_{50} values in the range of 35.9--122.0 \mu M. All other derivatives, except compound 4a, were inactive towards DPPH radical. …

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An Efficient Ligand-Free Method For The Transfer Hydrogenation Of Ketones And Aldehydes Catalyzed By Different Complexes, Sedat Yaşar, Suzan Çeki̇rdek, Ni̇lay Akkuş Taş, Semi̇ha Yildirim, İsmai̇l Özdemi̇r

Turkish Journal of Chemistry

A very efficient ligand-free method was developed for the transfer hydrogenation of ketones and aldehydes catalyzed by different metal complexes. With this catalytic system, the catalytic performance and catalytic stability of different Ir, Ru, and Pd complexes were more favorable than those of the previously reported systems for transfer hydrogenation. This ligand-free catalytic system showed good stability and excellent activity even with lower catalyst concentrations for the ketones and aldehydes tested.

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Application Of Experimental Design On Determination Of Aluminum Content In Saline Samples By Adsorptive Cathodic Stripping Voltammetry, Si̇nan Yilmaz, Betül Öztürk, Durmuş Özdemi̇r, Ahmet Emi̇n Eroğlu, Fatma Ni̇l Ertaş

Turkish Journal of Chemistry

Adsorptive cathodic stripping voltammetric determination of aluminum at ng mL^{-1} levels in salt samples based on the metal complexation with Calcon (1-(2-hydroxynaphthylazo)-2 naphthol-4-sulfonic acid) and the subsequent adsorptive deposition onto a hanging mercury drop electrode was studied. Central composite design was used as a design method. Several chemical and instrumental parameters (pH, ligand concentration, deposition time, deposition potential, and complexing time) were involved in the experimental design. Analytical parameters such as repeatability, linearity, and accuracy were also investigated and the detection limit was found as 0.32 ng mL^{-1}.

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Theoretical Study On The Addition Reaction Between Propadienylidene And Methyleneimine, Mengyuan Wang, Yungang Chen, Shanshan Ding, Yingde Wang, Qianchao Cao, Xiaojun Tan, Jinsong Gu

Turkish Journal of Chemistry

The reaction mechanism between propadienylidene and methyleneimine was systematically investigated employing the second-order Møller--Plesset perturbation theory (MP2) method with the 6 -- 31 + G* basis set. Geometry optimization, vibrational analysis, and energy property of the involved stationary points on the potential energy surface were calculated. The energies of the different species were corrected by single point energy calculations at the CCSD (T) // MP2 / 6 -- 31 + G* level. From the surface energy profile, one important initial intermediate characterized by a 3-membered ring structure was located via a transition state firstly. After that, 3 different products possessing …

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Electrochemistry Of 2,6-Diaminopurine On Multiwall Carbon Nanotube Modified Glassy Carbon Electrode, Ebru Mavi̇oğlu Ayan, Şükri̇ye Karabi̇beroğlu, Zekerya Dursun

Turkish Journal of Chemistry

The electrochemical oxidation of 2,6-diaminopurine (2,6-DAP) was studied in pH 7.4 phosphate buffer solution on multiwall carbon nanotube modified glassy carbon electrode (MWCNT/GCE) over a temperature range of 20 to 50 °C using cyclic voltammetry. 2,6-DAP oxidation on MWCNT/GCE showed a well-defined and irreversible oxidation peak at about 0.72 V vs. Ag/AgCl at pH 7.4. The oxidation potential of 2,6-DAP linearly varied with pH over the range of 3.0 to 10.0 with a slope of --0.0547 V/pH, implying that 2 protons were accompanied by 2 electrons transferred in the electrochemical reaction. The activation energy, Ea, of oxidation reaction was found …

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Potentiometric Determination Of Some Food Additives And Their Binding To A Polycationic Species Using Polyion Sensors, Nedi̇me Dürüst, Ali̇ Kayansalan

Turkish Journal of Chemistry

Polycation-sensitive membrane electrodes based on dinonylnaphthalene sulfonate (DNNS) were examined for the determination of some polyanions, namely xanthan (Xanth), alginate (Alg), carboxymethyl cellulose (CMC), and carrageenan (Carr). The potentiometric titrations of polyanionic analytes yielded sharp end points and correlative stoichiometries. After the determinations were successfully performed in saline, these polyanions were also determined in some food products consumed in Bolu (Turkey). In addition, the titration data were used to estimate the interactions between titrant and polyanionic analytes. The equilibrium constants, K_{eq}, and the number of titrant binding sites (n) per mole of analyte polyanion were calculated using Scatchard plots. The …

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Spectral, Electrochemical, Luminescence, And Dye-Sensitized Solar Cell Studies Of Mono And D-F Hetero Binuclear Cryptates, Arunachalam Vijayaraj, Raju Prabu, Ranganathan Suresh, Subbaiah Manoharan, Sambandam Anandan, Vengidusamy Narayanan

Turkish Journal of Chemistry

Mono and hetero binuclear cryptates, [Gd(III)ML]^+ [M = VO(IV), Co(II), Ni(II), Cu(II)], were synthesized by a 2-step method. The ligand L represents the deprotonated anionic cryptate obtained by the 2+3 condensation of tris-(2-aminoethyl)amine with 2,6-diformyl-4-nitrophenol. The complexes were characterized by elemental analysis, spectral, magnetic, and electrochemical studies. Fluorescence of Gd(III) ion in the cavity was quenched by the encapsulated Cu(II) and Ni(II) ions. [GdCoL(NO_3)]^+ cryptate had a high lifetime value compared to other cryptates. The cyclic voltammogram showed that the reduction potential values of [Gd(M)L] M = VO(IV), Co(II), Ni(II), and Cu(II) complexes were in the following order: Cu(II) > Ni(II) …

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Establishment Of An Electrochemical Rna Aptamer-Based Biosensor To Trace Nanomolar Concentrations Of Codeine, Mehdi Saberian, Davoud Asgari, Yadollah Omidi, Jaleh Barar, Hossein Hamzeiy

Turkish Journal of Chemistry

Codeine is an opium alkaloid with a great potential of abuse among opioid consumers. Detection of codeine is a routine procedure in the military and government of some countries for personnel recruitment. Therefore, a specific, selective, and easy to use method would be an important improvement in such detection procedures. According to previous reports, short single-stranded DNA or RNA sequences with high affinity and specificity to their targets, aptamers, could be used for designing an accurate and specific biosensor for codeine. This study introduces an aptamer-based biosensor for codeine detection in nanomolar concentrations by an electrochemical method, and ferrocene carboxylic …

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Environmentally Green Synthesis Of Thioformamide Derivatives, Ali Ramazani, Sang Woo Joo, Fatemeh Zeinali Nasrabadi

Turkish Journal of Chemistry

Reactions of isocyanides with thioacids in water proceeded smoothly at room temperature and in neutral conditions to afford thioformylamide and thioformamide derivatives in high yields. The reaction proceeded smoothly and cleanly under mild conditions and no side reactions were observed.

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A Phthalocyanine--Fluorescein Conjugate, İlker Ün, Yunus Zorlu, Hani̇fe İbi̇şoğlu, Fabienne Dumoulin, Vefa Ahsen

Turkish Journal of Chemistry

A phthalocyanine--fluorescein conjugate was designed and prepared. Its photophysical properties (electronic absorption and fluorescence) were determined and compared with those of an analogous derivative functionalized by a simple triazole without chromophore. It is likely to be used as a theranostic agent in photodynamic therapy.

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Potentiometric Study Of Equilibrium Constants Of A Novel Triazine--Thione Derivative And Its Stability Constants With Hg^{2+}, Cu^{2+}, Ni^{2+}, Pb^{2+}, And Zn^{2+} Metal Ions In Ethanol And Water Mixed, Fati̇h Polat, Hasan Atabey, Hayati̇ Sari, Alaaddi̇n Çukurovali

Turkish Journal of Chemistry

The deprotonation constants of 5-hydroxy-5,6-di-pyridin-2-yl-4,5-dihydro-2H-[1,2,4] triazine-3-thione (HPT) and the stability constants of its Hg^{2+}, Ni^{2+}, Cu^{2+}, Pb^{2+}, and Zn^{2+} ion complexes were studied in 20% ethanol and water mixed at 25 \pm 0.1 °C and ionic strength (I) of 0.1 M supported by NaCl. Four pK_a values of HPT were determined: 3.58, 6.30, 9.23, and 9.69. In various pH conditions, the different complex forms were formulated as ML, MHL, MH_2L, MH_3L, MH_4L, and MH_{-2}L between Hg^{2+}, Ni^{2+}, Cu^{2+}, Pb^{2+}, and Zn^{2+} ions and HPT. According to the potentiometric and spectrophotometric results, the HPT and Hg^{2+} combination formed a selective and …

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Flavonoid Constituents Of Sideritis Caesarea, Belkis Halfon, Ece Çi̇ftçi̇, Gülaçti Topçu

Turkish Journal of Chemistry

The acetone extract of the aerial parts of Sideritis caesarea Duman, Aytaç & Başer (Lamiaceae) afforded the flavonoids penduletin (1) and apigenin (2) and 6 glycosylated flavonoids, 4'-O-methyl-isoscutellarein-7-O-[6'''-O-acetyl-\beta-D-allopyranosyl- (1 \to 2)]-6\"-O-acetyl-\beta -D-glucopyranoside (3), 4'-O-methylhypolaetin- 7-O-[6'''-O-acetyl-\beta -D-allopyranosyl-(1 \to 2)]-6\"-O-acetyl-\beta- D-glucopyranoside (4), isoscutellarein-7-O-[6'''-O-acetyl-\beta- D-allopyranosyl-(1 \to 2)]-6\"-O-acetyl-\beta -D-glucopyranoside (5), isoscutellarein-7-O-[6'''-O-acetyl-\beta -D-allopyranosyl-(1 \to 2)]- \beta-D-glucopyranoside (6), 4'-O-methylhypolaetin-7-O- [6'''-O-acetyl-\beta -D-allopyranosyl-(1 \to 2)]-\beta-D- glucopyranoside (7), and hypolaetin-7-O-[6'''-O-acetyl-\beta- D-allopyranosyl-(1 \to 2)]-\beta -D-glucopyranoside (8). The compounds were identified by the use of 1D- and 2D-NMR and UV spectroscopic techniques and by comparisons with the reported data. The acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of the acetone, methanol, …

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Biotinylated N,N'-Diarylureas As Probes For The Activation Of Adenosine Monophosphate-Activated Kinase (Ampk), Vitaliy Sviripa, Michael D. Conroy, Wen Zhang, Alice Liu, David S. Watt

Turkish Journal of Chemistry

Biotinylated analogs of drug candidates provide useful tools for studying the drug--target protein interactions. Polyhalogenated N,N'diarylureas are potent activators of adenosine monophosphate-activated kinase (AMPK) and potentially promising agents for the treatment of cancer. Various biotinylated versions of these N,N'-diarylureas were synthesized and evaluated in AMPK-activation studies.

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Quasielastic Light Scattering Studies Of Polypeptides: Evidence For Chain Extension In Solution, Mehmet Bahatti̇n Baysal, Çi̇ğdem Karadağ

Turkish Journal of Chemistry

Dynamic light scattering and viscosimetric methods were used to study polypeptides including polyleucine, poly (\gamma-benzyl-L-glutamate), poly (\alpha-L-glutamic acid), and polyproline II. Chain extension showing rod-like and flexible conformations occurred in poly(\gamma -benzyl-L-glutamate) and polyproline II solutions as these solutions were diluted in glacial acetic acid or in a mixed solvent of acetic acid and dichloromethane. The elongation of chains in poly(\gamma -benzyl-L-glutamate) and polyproline II solutions was studied by dynamic light scattering and viscosimetric methods. This nonenzymatic growth of peptide chains provides data on primordial synthesis of protein molecules in the absence of cell machinery and for this reason these …

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Full-Text Articles in Physical Sciences and Mathematics

Advances In The Chemistry Of Pyrazolopyrazoles, Rizk Elsyad Khidre, Hanan Ahmed Mohamed, Bakr Fathy Abdelwahab

Turkish Journal of Chemistry

Fabrication Of Layer-By-Layer Deposited Films Containing Carbon Nanotubes And Poly(Malachite Green) As A Sensor For Simultaneous Determination Of Ascorbic Acid, Epinephrine, And Uric Acid, Jahan Bakhsh Raoof, Reza Ojani, Mehdi Baghayeri

Turkish Journal of Chemistry

Electrochemical Properties Of 1,3-Disubstituted Methyl Methoxy Phenyl-5-Phenylformazans And Comparison With Spectral Properties, Habi̇be Tezcan, Güler Ekmekci̇, Mehmet Levent Aksu

Turkish Journal of Chemistry

A New Method For Calculating The Vibration-Rotation-Tunneling Spectra Of Molecular Clusters And Its Application To The Water Dimer, Mahi̇r Erteki̇n Ocak

Turkish Journal of Chemistry

Mechanochemical Modification Method Used In The Development Of New Composite Materials Based On Epoxy Binder And Natural Minerals, Umida Ziyamukhamedova, Dilshod Djumabaev, Botirali Shaymardanov

Turkish Journal of Chemistry

Synthesis And Characterization Of Ni(Ii) And Cu(Ii) Complexes Derived From Novel Phenolic Mannich Bases, Nurgün Büyükkidan, Sali̇h Özer

Turkish Journal of Chemistry

Molecular Docking And Qsar Study On Imidazole Derivatives As 14 /Alpha -Demethylase Inhibitors, Asghar Davood, Maryam Iman

Turkish Journal of Chemistry

Enaminonitriles In Heterocyclic Synthesis: Synthesis And Biological Evaluation Of Novel Indeno[2,1-B]Thiophene Derivatives, Ahmed A. Fadda, Abd El Galil M. Khalil, Eman H. Tawfik

Turkish Journal of Chemistry

Synthesis, Characterization, And Swelling Behaviors Of A Ph-Responsive Cmc-G-Poly(Aa-Co-Amps) Superabsorbent Hydrogel, Yizhe Wang, Xiaoning Shi, Wenbo Wang, Aiqin Wang

Turkish Journal of Chemistry

Synthesis, Characterization, And Antimicrobial Activity Of Some New Phosphorus Macrocyclic Compounds Containing Pyrazole Rings, Tarik El-Sayed Ali, Salah Abdel-Aziz Abdel-Ghaffar, Kamilia Mohamed El-Mahdy, Somaia Mohamed Abdel-Karim

Turkish Journal of Chemistry

Removal Of Cr(Iii) And Cu(Ii) Using Oly(2-Chloroaniline)/Polyvinylidenefluoride Composite Cation-Exchange Membranes By Donnan Dialysis, Esengül Kir, Sabri̇ye Perçi̇n Özkorucuklu, Tuğba Sardohan Köseoğlu, Esi̇n Karamizrak

Turkish Journal of Chemistry

Antimicrobial Activity And Chemical Composition Of The Essential Oils Of Mosses (Hylocomium Splendens (Hedw.) Schimp. And Leucodon Sciuroides (Hedw.) Schwägr.) Growing In Turkey, Tayyi̇be Beyza Cansu, Büşra Yayli, Turan Özdemi̇r, Nevzat Batan, Şengül Alpay Karaoğlu, Nuretti̇n Yayli

Turkish Journal of Chemistry

Synthesis And Characterization Of Thermally Stable Camphor-Based Polyimide--Clay Nanocomposites, Murat Yi̇ği̇t, Turgay Seçki̇n, Beyhan Yi̇ği̇t, Süleyman Köytepe

Turkish Journal of Chemistry

Ionic Liquid Mediated Synthesis, Reactions, And Insecticidal Activity Of 1-[(1h-Benzoimidazol-2-Yl)Amino]Spiro[Azetidine-4,4'-[4'H]Chroman]-2-Ones, Dr Kanti Sharma, Renuka Jain

Turkish Journal of Chemistry

Synthesis And Cytotoxic Activity Of Some 2-(2,3-Dioxo-2,3-Dihydro-1h-Indol-1-Yl)Acetamide Derivatives, Özlem Akgül, Ayşe Hande Tari̇koğullari, Fadi̇me Aydin Köse, Petek Ballar Kirmizibayrak, Mehmet Varol Pabuççuoğlu

Turkish Journal of Chemistry

Synthesis And Antimicrobial Investigation Of Some 5h-Pyridazino[4,5-B]Indoles, İlker Avan, Alaetti̇n Güven, Kiymet Güven

Turkish Journal of Chemistry

Synthesis And Evaluation Of Acetylcholineesterase Inhibitory Potential And Antioxidant Activity Of Benzothiazine Derivatives, Durre Shahwar, Uzma Sana, Naeem Ahmad

Turkish Journal of Chemistry

An Efficient Ligand-Free Method For The Transfer Hydrogenation Of Ketones And Aldehydes Catalyzed By Different Complexes, Sedat Yaşar, Suzan Çeki̇rdek, Ni̇lay Akkuş Taş, Semi̇ha Yildirim, İsmai̇l Özdemi̇r

Turkish Journal of Chemistry

Application Of Experimental Design On Determination Of Aluminum Content In Saline Samples By Adsorptive Cathodic Stripping Voltammetry, Si̇nan Yilmaz, Betül Öztürk, Durmuş Özdemi̇r, Ahmet Emi̇n Eroğlu, Fatma Ni̇l Ertaş

Turkish Journal of Chemistry

Theoretical Study On The Addition Reaction Between Propadienylidene And Methyleneimine, Mengyuan Wang, Yungang Chen, Shanshan Ding, Yingde Wang, Qianchao Cao, Xiaojun Tan, Jinsong Gu

Turkish Journal of Chemistry

Electrochemistry Of 2,6-Diaminopurine On Multiwall Carbon Nanotube Modified Glassy Carbon Electrode, Ebru Mavi̇oğlu Ayan, Şükri̇ye Karabi̇beroğlu, Zekerya Dursun

Turkish Journal of Chemistry

Potentiometric Determination Of Some Food Additives And Their Binding To A Polycationic Species Using Polyion Sensors, Nedi̇me Dürüst, Ali̇ Kayansalan

Turkish Journal of Chemistry

Spectral, Electrochemical, Luminescence, And Dye-Sensitized Solar Cell Studies Of Mono And D-F Hetero Binuclear Cryptates, Arunachalam Vijayaraj, Raju Prabu, Ranganathan Suresh, Subbaiah Manoharan, Sambandam Anandan, Vengidusamy Narayanan

Turkish Journal of Chemistry

Establishment Of An Electrochemical Rna Aptamer-Based Biosensor To Trace Nanomolar Concentrations Of Codeine, Mehdi Saberian, Davoud Asgari, Yadollah Omidi, Jaleh Barar, Hossein Hamzeiy

Turkish Journal of Chemistry

Environmentally Green Synthesis Of Thioformamide Derivatives, Ali Ramazani, Sang Woo Joo, Fatemeh Zeinali Nasrabadi

Turkish Journal of Chemistry

A Phthalocyanine--Fluorescein Conjugate, İlker Ün, Yunus Zorlu, Hani̇fe İbi̇şoğlu, Fabienne Dumoulin, Vefa Ahsen

Turkish Journal of Chemistry

Potentiometric Study Of Equilibrium Constants Of A Novel Triazine--Thione Derivative And Its Stability Constants With Hg^{2+}, Cu^{2+}, Ni^{2+}, Pb^{2+}, And Zn^{2+} Metal Ions In Ethanol And Water Mixed, Fati̇h Polat, Hasan Atabey, Hayati̇ Sari, Alaaddi̇n Çukurovali

Turkish Journal of Chemistry

Flavonoid Constituents Of Sideritis Caesarea, Belkis Halfon, Ece Çi̇ftçi̇, Gülaçti Topçu

Turkish Journal of Chemistry

Biotinylated N,N'-Diarylureas As Probes For The Activation Of Adenosine Monophosphate-Activated Kinase (Ampk), Vitaliy Sviripa, Michael D. Conroy, Wen Zhang, Alice Liu, David S. Watt

Turkish Journal of Chemistry

Quasielastic Light Scattering Studies Of Polypeptides: Evidence For Chain Extension In Solution, Mehmet Bahatti̇n Baysal, Çi̇ğdem Karadağ

Turkish Journal of Chemistry