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Full-Text Articles in Physical Sciences and Mathematics
Microfabricated Fluidic Devices For Biological Assays And Bioelectronics, Anna V. Bickham
Microfabricated Fluidic Devices For Biological Assays And Bioelectronics, Anna V. Bickham
Theses and Dissertations
Microfluidics miniaturizes many benchtop processes and provides advantages of low cost, reduced reagent usage, process integration, and faster analyses. Microfluidic devices have been fabricated from a wide variety of materials and methods for many applications. This dissertation describes four such examples, each employing different features and fabrication methods or materials in order to achieve their respective goals. In the first example of microfluidic applications in this dissertation, thermoplastics are hot embossed to form t-shaped channels for microchip electrophoresis. These devices are used to separate six preterm birth (PTB) biomarkers and establish a limit of detection for each. The next chapter …
Conduction Mapping For Quality Control Of Laser Powder Bed Fusion Additive Manufacturing, Chance M. Baxter
Conduction Mapping For Quality Control Of Laser Powder Bed Fusion Additive Manufacturing, Chance M. Baxter
Theses and Dissertations
A process was developed to identify potential defects in previous layers of Selective Laser Melting (SLM) Powder Bed Fusion (PBF) 3D printed metal parts using a mid-IR thermal camera to track infrared 3.8-4 m band emission over time as the part cooled to ambient temperature. Efforts focused on identifying anomalies in thermal conduction. To simplify the approach and reduce the need for significant computation, no attempts were made to calibrate measured intensity, extract surface temperature, apply machine learning, or compare measured cool-down behavior to computer model predictions. Raw intensity cool-down curves were fit to a simplified functional form designed to …