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Physical Sciences and Mathematics Commons™
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Full-Text Articles in Physical Sciences and Mathematics
Double Cysteine Mutations In Staphylococcal Nuclease: The Effect Of Artificially Introduced Disulfide Bonds On Protein Structure And Stability, Anna Terry
Inquiry: The University of Arkansas Undergraduate Research Journal
Since a protein's function depends on its structure, basic research in protein structure facilitates the solution of many practical problems, such as the synthesis of more effective medicines. With this larger goal in sight, the purpose of this research project is to understand better the chemical principles that underlie protein structure and stability. Disulfide bonds are a potentially stabilizing feature of many proteins. They may form between cysteine residues in close proximity to one another if the orientation is favorable. Often found in proteins produced by organisms that grow at high temperatures, disulfide bonds may anchor side chains together, making …
Design, Implementation, And Evaluation Of Virtual Interface Architecture For Power Pc Machines, Ben Mckenzie
Design, Implementation, And Evaluation Of Virtual Interface Architecture For Power Pc Machines, Ben Mckenzie
Inquiry: The University of Arkansas Undergraduate Research Journal
The Virtual Interface Architecture (VIA) standard is a low-latency protocol that was designed for use in high-performance networks. VIA improves performance by reducing overhead in messaging. This research has two components. The first part of this research project is the development of a new tool for measuring the performance of a VIA implementation and comparing it to the more traditional high-overhead protocols used on the Internet. The development of the tool represents a significant contribution in and of itself, since the tool has been put into the public domain and will likely become useful by Lima users, both for measuring …
An Analysis Of The Theory Of Functions Of One Real Variable, Robert J. Reed
An Analysis Of The Theory Of Functions Of One Real Variable, Robert J. Reed
Inquiry: The University of Arkansas Undergraduate Research Journal
Few undergraduates are aware that the Riemann integral taught in introductory calculus courses has only limited application-essentially this integral can be used only to integrate continuous functions over intervals. The necessity to integrate a broader class of functions over a wider range of sets that arises in many applications motivates the theory of abstract integration and functional analysis. The founder of this theory was the French mathematician Henri Lebesgue, who in 1902 defined the "Lebesgue measure" of subsets of the real line. The purpose of this project is to elucidate the theory of abstract measure spaces and of important spaces …
Studies Of Tryptophans In Membrane- Spanning "Walp" Peptides By Deuterium Nmr Spectroscopy, Nichole Reed
Studies Of Tryptophans In Membrane- Spanning "Walp" Peptides By Deuterium Nmr Spectroscopy, Nichole Reed
Inquiry: The University of Arkansas Undergraduate Research Journal
WALP pep tides of sequence acetyl-Gly-Trp-Trp-(Leu-Ala)-Trp-Trp-Ala-ethanolamine insert into lipid bilayers as membrane-spanning a-helices and modulate the lipid phase behavior as functions of n and the lipid acyl chain length. A key feature of the WALP peptides is the positioning of tryptophan (Trp) indole rings at the membrane/water interface. For the examples WALP19 with n = 6.5 and WALP23 with n = 8.5, we have labeled individual indoles with deuterium and incorporated the labeled peptides in oriented, hydrated bilayers of Dimyristoyl-phosphatidylcholine (DMPC). Deuterium NMR spectra from these samples show sharp resonances when the membrane normal is aligned either parallel (Beta = …