Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
Articles 1 - 2 of 2
Full-Text Articles in Physical Sciences and Mathematics
Investigating Ionic Current Rectification As A Means Of Controllable Drug Delivery Using Silica Nanoparticles And Nano Porous Membranes, Katie L. Nolan
Investigating Ionic Current Rectification As A Means Of Controllable Drug Delivery Using Silica Nanoparticles And Nano Porous Membranes, Katie L. Nolan
Honors College Theses
This project investigates a novel ionic current rectification (ICR) phenomenon created by the opening and closing of nanopores by charged silica nanoparticles (SNPs) under electrophoretic flow. This voltage-controlled opening and closing of the pores can be exploited to allow delivery of nicotine through the pores at programmable intervals. The ICR phenomenon was thoroughly investigated by varying pH, buffer concentration, SNP concentration, and applied voltage range. The mechanism was also verified by testing with a 2-, 3-, and 5-electrode system. Potential cake layer formation was demonstrated in a longer ICR test, and the implications of this on the drug delivery mechanism …
Electrolytic Oxidative Coupling Of Alcohols With Aldehydes To Form Esters, Katherine L. Verboom
Electrolytic Oxidative Coupling Of Alcohols With Aldehydes To Form Esters, Katherine L. Verboom
Honors College Theses
There are copious amounts of naturally occurring and synthetic esters known that have a wide range of applications in industry to produce fine chemicals. Traditional methods of ester synthesis involve a reaction between a carboxylic acid and an alcohol in the presence of a Bronsted acid catalyst. The primary objective of this research project was to carry out the ester synthesis using the electrochemical coupling of aldehydes with alcohols instead of with a Bronsted acid catalyst because the electrochemical coupling would be an all-around better alternative of ester synthesis than the traditional method of using the catalyst. Electrochemistry has long …