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Full-Text Articles in Physical Sciences and Mathematics
Synthesis, Characterization And Cell Viability Of Novel Tripodal Amines, Kinsley Lupton
Synthesis, Characterization And Cell Viability Of Novel Tripodal Amines, Kinsley Lupton
Honors College Theses
Cancer, over the years, has become a much more prevalent focus for the scientific community. Organizations and laboratories all over the world have spent countless hours searching for a cure, trying to learn more about what makes cancer so powerful and what is the best way to stop its growth. Iron-chelation drugs were already on the market, and it was shown that they did have the ability to act as both iron-chelators and anticancer drugs. Most of these iron-chelating drugs are not as effective at killing cancer cells as the medical field desires. Novel iron-chelating tris-indolyl derivatives, GSO2, GSO4 and …
Synthesized Tripodal Amine As Potential Anti-Cancer Therapeutic, Abigail G. Mcnamee
Synthesized Tripodal Amine As Potential Anti-Cancer Therapeutic, Abigail G. Mcnamee
Honors College Theses
Cancer remains a prevalent disease today. This disease may manifest itself in many different ways and affect a variety of tissues with everything from the brain to the blood. With this wide diversity of cancer types, treatment can be complicated since there is not a “one size fits all” treatment for the disease. Surgery, radiation, and chemotherapy are all options that must be weighed with their benefits and side effects. Ultimately though, there are not enough effective treatment options available for every type of cancer. This leaves many with the grim prognosis of never being cured. With this clear need …
Caspases And Cancer: Connections Through Circular Dichroism Spectroscopy, Sarah M. Hethcox
Caspases And Cancer: Connections Through Circular Dichroism Spectroscopy, Sarah M. Hethcox
Honors College Theses
While excessive cell death inevitably leads to negative effects, the endurance of damaged cells in the presence of death signals can be equally detrimental to health. Apoptosis, or programmed cell death, is a highly regulated process in which cues from within or from outside a cell can trigger an irreversible sequence of signals that carry out cell destruction known as the apoptotic cascade. A group of enzymes called caspases play a vital role in this cascade with some participating as initiators and others acting as effectors of protein cleavage and intracellular breakdown. Although it is normal for the activity of …