Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Physical Sciences and Mathematics
X-Ray Absorption Fine Structure Studies Of Calcium Silicate Hydrate Biomaterials In Drug Delivery, Xiaoxuan Guo
X-Ray Absorption Fine Structure Studies Of Calcium Silicate Hydrate Biomaterials In Drug Delivery, Xiaoxuan Guo
Electronic Thesis and Dissertation Repository
Calcium silicate hydrate (CSH), a new type of bioceramics, has gained significant attention in hard tissue restoration because of their impressive role in the stimulation of osteoblast proliferation and differentiation in vitro. The further development of mesoporous bioceramics opens up new opportunities for drug delivery in hard tissue therapies. In this thesis, interaction mechanisms of drug molecules with CSH of different morphologies and CSH/polymer composites, imaging of drug distributions in CSH carriers in nanoscale, and the biomineralization mechanisms of CSH in vitro during drug release are extensively investigated using X-ray absorption near edge structure (XANES) and scanning transmission X-ray …