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Design, Synthesis, And Applications Of Nano-Assemblies Based On Amphiphilic Macromolecules, Hui Wang
Design, Synthesis, And Applications Of Nano-Assemblies Based On Amphiphilic Macromolecules, Hui Wang
Doctoral Dissertations
Recent progress in nanotechnology has been significantly impacting a variety of areas such as utilization in microelectronics, multiphase catalysis, sensing and therapeutics. Our interests are to develop new nanomaterials to understand their structure-property relationships and to utilize them for various applications. In this thesis, we discuss our findings on the design, synthesis and applications of nanomaterials formed by self-assembly of amphiphilic molecules. Micelles are self-assembled nanostructures formed by amphiphilic molecules. They are capable of sequestering hydrophobic guest molecules in an aqueous environment. Other than surfactants, micelles can also be formed by amphiphilic polymers or dendrimers, which are macromolecular surfactants in …
Self-Assembly And Stimuli Responsive Disassembly Of Dendritic And Oligomeric Amphiphiles, Krishna Reddy Raghupathi
Self-Assembly And Stimuli Responsive Disassembly Of Dendritic And Oligomeric Amphiphiles, Krishna Reddy Raghupathi
Doctoral Dissertations
Stimuli response is a fundamental process prevalent in all living systems, where a specific function (response) is generated in the presence of a given environmental cue (stimulus). Engineering materials for this process is often accomplished through another basic process, “self-assembly”. By understanding the key aspects of these processes scientists have developed a broad range of materials for a wide array of applications. This dissertation will primarily focus on developing stimuli responsive nanocarriers based on supramolecular assemblies of amphiphilic dendrimers and oligomers for safe transport and selective release of molecular cargo. Our concurrent goal is to also investigate several parameters which …