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Physical Sciences and Mathematics Commons

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Doctoral Dissertations

Organic Chemistry

Sensing

Publication Year

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Full-Text Articles in Physical Sciences and Mathematics

Modulating Nanoparticle-Protein Interactions Through Covalent Or Noncovalent Approach For Biomedical Applications, Jingjing Gao Mar 2020

Modulating Nanoparticle-Protein Interactions Through Covalent Or Noncovalent Approach For Biomedical Applications, Jingjing Gao

Doctoral Dissertations

Discoveries at the interface of chemistry, biology, and materials science have emerged as a powerful route to impact life science in this century. My research in the Thayumanavan group is focused on problems at this interface. A common theme of all the six projects is the use of modern synthetic organic chemistry to build interesting, novel macromolecules which are chemically rich, to study the molecular self-assembly behavior in solution and then translate to solve problems in the biomedical area. By addressing the design challenge to prepare novel amphiphiles with desired functional groups, controlled molecular weight and the ability to respond …


Design And Self-Assembly Of Responsive Scaffolds For Food And Sensing Applications, Uma Sridhar Mar 2019

Design And Self-Assembly Of Responsive Scaffolds For Food And Sensing Applications, Uma Sridhar

Doctoral Dissertations

Developing an understanding of how molecules, materials and complex systems contribute to biological functions is important since the interpretation of such mechanisms paves the way to further the development of materials that replicate natural functions or impart the observed properties to synthetic materials. The self-assembly of stimuli-responsive scaffolds based on micelles, liposomes, hydrogels and thin films has been of considerable interest. These systems need to be endowed with certain design features which influence the self-assembly and the responsiveness of the scaffold when subjected to external stimuli which could be physical, chemical or biological in nature. This kind of insight is …


Inkjet Printing For Biosensing And Security Applications, Brian Creran Nov 2015

Inkjet Printing For Biosensing And Security Applications, Brian Creran

Doctoral Dissertations

The adaptation of inkjet printing technology has recently been used to create controlled high throughput micro- and nano-scaled structures. Coupling this technique with gold nanoparticles in our research has produced new platforms for biosensors, chemical patterning, and anti-counterfeiting applications. In this presentation, we will highlight promising fabrication strategies including the development of test strips for the determination of bacteria in drinking water as well as the use of patterned nanoparticles for security applications.