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Development Of Supercritical Processes For Particle Coating / Encapsulation With Polymers, Yulu Wang

Dissertations

This work presents the investigation of particle coating using supercritical fluid processes as novel coating approaches to coat particles from 20 nanometers to 500 microns with different polymers. Particle coating using different supercritical technologies of a modified rapid expansion of a supercritical solution (RESS) for particle coating and a supereritical antisolvent (SAS) process was described.

In the modified RESS process for particle coating, experiments were performed using a pilot-scale supercritical apparatus, glass beads as host particles and two different polymers as coating materials. By adjusting temperature and pressure, the polymer nucleated and precipitated onto the surface of the host particles …