Physical Sciences and Mathematics Commons^™

Atomic Oxygen Adsorption And Absorption On Rh(111) And Ag(111), Jonathan Derouin

Dissertations

A central question in the field of heterogeneous catalysis is how surface structure and subsurface species influence catalytic behavior. One key to answering that question is determining which surface structures and subsurface species are present under catalytically relevant conditions. This dissertation presents results of Auger electron spectroscopy, low energy electron diffraction, temperature programmed desorption, and scanning tunneling microscopy experiments on oxidized Rh(111) and Ag(111) crystals. Exposing Rh(111) to O2 produced a predominately (2 × 1) adlayer, but even after extended dosing, (2 × 2) domains were also present. Exposing Rh(111) to atomic oxygen yielded O coverages greater than 0.5 ML …

The Utilization Of Liquid Chromatography Tandem Mass Spectrometry And Related Techniques For The Analysis And Identification Of Emerging Contaminants In Aqueous Matrices, Matthew Reichert

Dissertations

Environmental pollutants can be found in many ecosystems and cover many different compound classes. The Environmental Protection Agency is responsible for monitoring and regulating several of these classes of compounds which daily enter the environment. However, there are still hundreds, if not thousands, of compounds present in the environment which have yet to be regulated or even identified. The discovery and identification of these unknown emerging pollutants is crucial for the prevention of potential human health risks and irreversible ecological damage.

The research presented is divided into two projects. The first part of this research investigates the disinfectant 3-Bromo-1-chloro-5,5-dimethylhydantoin, which …

Development Of Folate Directed, Protein Based Photodynamic Therapy Agents, Rojenia Jones

Dissertations

To attack cancer cells in a specific manner, we have developed a folate-targeted, photodynamic therapy (PDT) agent. The folate (FA) and the chlorin e6 (Ce6) photosensitizer were attached to bovine serum albumin (BSA) using carbodiimide chemistry. Since over 50% of cancers overexpress folate receptors, FA-BSA-Ce6 can be taken up by them and is an effective PDT agent. Hela cells exposed to FA-BSA-Ce6 in the dark showed no cytotoxicity. Upon exposure to light, the conjugate was dose (time and concentration) dependent. Concentrations less than or equal to 2 µM were not effective at killing Hela cells but concentrations of at 5 …

Exploring Conditions For The Enhancement Of Acene Semiconductors Through The Use Of The Diels-Alder Reaction, Brittni Qualizza Qualizza

Dissertations

This dissertation demonstrates the application of SAMs to the surface of acene crystals, specifically of tetracene and rubrene, using the Diels-Alder reaction. The second chapter details preliminary reaction results and two analytical methods which were employed to confirm adsorption of the dienophile on the surface of single crystals, tetracene and rubrene. These were mass spectrometry and X-ray photoelectron spectroscopy (XPS). Mass spectrometry experiments distinguish the chemical identity of adduct on the crystals and also it discerned chemi- and physisorbed molecules from one another. XPS was used to prove face selectivity of the reaction by the detection of dichloromaleic anhydride. From …