Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
Articles 1 - 3 of 3
Full-Text Articles in Physical Sciences and Mathematics
Oxidative C–C And C–Heteroatom Reactivity Of High-Valent Nickel Complexes, Sofia Marie Smith
Oxidative C–C And C–Heteroatom Reactivity Of High-Valent Nickel Complexes, Sofia Marie Smith
Arts & Sciences Electronic Theses and Dissertations
ABSTRACT OF THE DISSERTATION
Oxidative C–C and C–Heteroatom Reactivity of High-Valent Nickel Complexes
by
Sofia M. Smith
Doctor of Philosophy in Chemistry
Washington University in St. Louis, 2019
Professor Liviu M. Mirica, Chair
Professor Kevin D. Moeller, Co-Chair
Nickel catalysts are commonly used for cross-coupling reactions such as Negishi, Kumada and Suzuki couplings. While Ni(0), Ni(I), and Ni(II) intermediates are most relevant in these transformations, Ni(III) and Ni(IV) species have also been recently proposed to play a role in catalysis. The formation of C–C and C–heteroatom bonds plays a fundamental role in organic transformations, and today cross-coupling reactions are one …
Oxidative C-C Bond Formation Reactivity Of High Valent Nickel And Palladium Complexes, Michael Benjamin Watson
Oxidative C-C Bond Formation Reactivity Of High Valent Nickel And Palladium Complexes, Michael Benjamin Watson
Arts & Sciences Electronic Theses and Dissertations
The development of both palladium and nickel catalysis over the past several decades has led to the ability to perform a multitude of C-C coupling, C-Heteroatom coupling, and C-H functionalization reactions. These reactions typically utilize a catalytic cycle involving Pd0/II/IV and Ni0/II. While using these types of catalytic cycles one can create a multitude of different hard to make bonds, it is always important to keep expanding what we view as potential catalytic intermediates to keep developing new cycles capable of new transformations. One such way to expand our knowledge of these catalytic cycles is to look at the oxidation …
High-Valent Organometallic Palladium And Nickel Complexes And Their Roles In Carbon-Carbon And Carbon-Heteroatom Bond Formation Reactions, Jason Wesley Schultz
High-Valent Organometallic Palladium And Nickel Complexes And Their Roles In Carbon-Carbon And Carbon-Heteroatom Bond Formation Reactions, Jason Wesley Schultz
Arts & Sciences Electronic Theses and Dissertations
The development of palladium catalysis has been influential in a wide range of organic transformations, in particular C-C coupling, C-Heteroatom coupling and C-H functionalization reactions. These catalytic transformations normally proceed through the Pd0/II catalytic cycle. These reactions are remarkably useful, however, they suffer from two major problems: -hydride elimination and palladium black deposition. To circumvent these problems, recent reports have been focused on developing novel organic transformations proceeding through high-valent palladium and nickel catalytic cycles.
To this point, we recently reported the isolation and characterization of various mononuclear PdIII complexes using the tetradentate ligands, N,N-di-alkyl-2,11-diaza[3.3](2,6)pyridinophane (RN4, R = tBu, iPr, …