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- Calixarene (2)
- Spirocycle (2)
- Spirolactam (2)
- Anion sensor (1)
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- Diamine (1)
- Diastereoisomers (1)
- Enterobacter agglomerans (1)
- Enterococcus faecium (1)
- Ester aminolysis (1)
- Fluorescence sensing (1)
- Homochiral diamine (1)
- Ion selective electrodes (ISE) (1)
- Menaquinone (1)
- Mercury (1)
- Molecular recognition (1)
- Neonatal gut microflora (1)
- Nitrile (1)
- Potentiometry (1)
- Ratiometric (1)
- Serratia marcescens (1)
- Silver (1)
- Vitamin K (1)
Articles 1 - 6 of 6
Full-Text Articles in Physical Sciences and Mathematics
Newly Identified Vitamin K-Producing Bacteria Isolated From The Neonatal Faecal Flora, Gordon Cooke, John Behan, Mary Costello
Newly Identified Vitamin K-Producing Bacteria Isolated From The Neonatal Faecal Flora, Gordon Cooke, John Behan, Mary Costello
Articles
Fat-soluble vitamin K is an essential component of the blood clotting process. Menaquinones are the naturally occurring form of vitamin K identified in bacteria. Lipid extracts were made from three bacteria originally isolated from the human neonatal gut and identified as Enterobacter agglomerans, Serratia marcescens and Enterococcus faecium. Following preparative thin layer chromatography (TLC), the lipid extracts were subjected to liquid chromatography-mass spectrometry (LC-MS) analysis. Peak analysis of the LC-MS data showed that the three bacteria produce various forms of menaquinone.
Implications Of Mass Education On Chemistry Higher Education, Christine O'Connor
Implications Of Mass Education On Chemistry Higher Education, Christine O'Connor
Articles
The following paper discusses the implications of government policy for widening access and participation in third level institutes. The increase in ‘non-traditional’ students has been widely recognised on an international scale; however, some issues of inequality still exist. The ‘struggles’ associated with widening participation and the creation of a ‘new’ student type are discussed, with particular reference to chemistry education. A change is needed with regard to the pedagogical approach taken by staff in order to cater for a diverse student body comprising a broad range of learner types, and this must be supported both at departmental and institutional levels. …
A Chloride Selective Calix[4]Arene Optical Sensor Combining Urea Functionality With Pyrene Excimer Transduction, Benjamin Schazmann, Dermot Diamond
A Chloride Selective Calix[4]Arene Optical Sensor Combining Urea Functionality With Pyrene Excimer Transduction, Benjamin Schazmann, Dermot Diamond
Articles
A neutral 2-site chloride selective compound has been developed (3), based on a 1,3- alternate tetrasubstituted calix[4]arene providing a preorganised supramolecular scaffold. The resultant supramolecular cavity is amongst the first to combine urea functional groups bridged with single methylene spacers to pyrene moieties. It combines a naturally and synthetically proven H-bonding system with the elegant ratiometric fluorescent signalling properties of an intramolecular pyrene excimer system, triggered by conformational changes upon anion coordination. The excimer emission of 3 is quenched, with a simultaneous rise in the monomer emission solely by the chloride anion amongst a wide variety of anions tested. 3 …
Spirobicyclic Diamines 2: Synthesis Of Homochiral Diastereoisomeric Proline Derived [4,4]-Spirolactams, Fintan Kelleher, Sinead Kelly
Spirobicyclic Diamines 2: Synthesis Of Homochiral Diastereoisomeric Proline Derived [4,4]-Spirolactams, Fintan Kelleher, Sinead Kelly
Articles
L-Proline derived diastereoisomeric [4.4]-spirolactams have been prepared by a reductive-amination reaction of (R)- or (S)-alanine methyl ester followed by thermal cyclisation of the resulting amine onto the proline ester group in refluxing toluene. Under similar conditions (R)- or (S)-phenylalanine methyl ester gave no cyclisation products, while R- or S-a-methylbenzylamine required treatment with NaNH2 in refluxing toluene to induce cyclisation giving diastereoisomeric [4.4]-spirolactams
Spirobicyclic Diamines 1: Synthesis Of Proline-Derived Spirolactams Via Thermal Intramolecular Ester Aminolysis, Fintan Kelleher, Sinead Kelly
Spirobicyclic Diamines 1: Synthesis Of Proline-Derived Spirolactams Via Thermal Intramolecular Ester Aminolysis, Fintan Kelleher, Sinead Kelly
Articles
Proline derived [4.4]-spirolactams have been synthesised in good yields by a reductive-amination reaction followed by thermal cyclisation of the resulting amine onto the proline ester group in refluxing toluene. The synthesis of the corresponding [4.5]-spirolactams by the same method gave much reduced yields.
Development Of A Calix[4]Arene Sensor For Soft Metals Based On Nitrile Functionality, Benjamin Schazmann, Dermot Diamond
Development Of A Calix[4]Arene Sensor For Soft Metals Based On Nitrile Functionality, Benjamin Schazmann, Dermot Diamond
Articles
The current work is amongst the first to examine the potential usefulness of the nitrile functional group in potentiometric analytical sensors for soft metals. Nitrile functionality has hereby been incorporated into a calix[4]arene skeleton to give a series of new cation selective hosts. The analytical sensing behaviour of these hosts was examined by Ion Selective Electrode (ISE) based potentiometry. In all cases a preference for soft metals was observed, explained primarily in terms of soft–soft compatibility between calix[4]arene nitrile hosts and metal guests in combination with a classical ‘lock and key’ best fit mechanism. Hosts 2, 3 and 4 showed …