Physical Sciences and Mathematics Commons^™

Increasing Expression Of Civic-Engagement Values By Students In A Service-Learning Chemistry Course, Audrey E. Mcgowin, Rebecca Teed

Chemistry Faculty Publications

A service-learning course at a midsized Midwestern research university was modified over a period of six years to integrate best-practice pedagogies that have been shown to increase civic engagement by students. Best-practice pedagogies included regular interaction with community partner(s), significant time spent on the service activity, and regular reflection (written and verbal) on the implications of the service activity. Besides water quality monitoring, students performed private well water analysis, wrote multiple formal reflection papers, and presented a public talk on the results of their project that included significant discussion time with community partners. Authentic expression of civic engagement values was …

Pharmaflights: Fragment Based Drug Discovery Based On Chalcones With A 3,4,5-Trimethoxy Substitution On Ring B., Cody Fourman

The University Honors Program

The 3,4,5-trimethoxyphenyl motif is a common structural feature of a number of natural occurring antimitotic agents, especially those capable interacting with microtubules such as the cis-stilbene, combrestatin A-4. Chalcones possessing this pharmacophore have likewise been demonstrated to exhibit a diverse range of biological actions including anticancer, anti-invasive, antioxidant, and anti-inflammatory activities. As part of an experiential learning experience in academic drug discovery termed WSU PharmaFlights, so-called flights of 6-10 molecules based on a particular biologically relevant structural pattern on the privileged chalcone scaffold are to be designed, synthesized, and spectroscopically characterized as a starting point for lead-development with potential biological …

Chlorination Of 3-Arylsydnones With Iodine Monochloride, Ben Owens

The University Honors Program

An improved method for the chlorination at the 4-position of 3- arylsydnones 1 was developed, using iodine monochloride (ICl) dissolved in DCM. 1,3,4-Oxadiazol-2(3H)-ones 3 were then synthesized from the resultant 4-chloro-3-arylsydnones 2. The scope and limitations will be presented.

Investigating Potential Pollutant Sources Causing Lack Of Biodiversity In Lytle Creek And Indian Run, Audrey E. Mcgowin, Amira Alsenbel, Harry Mcvey, Lori Williams, Taylor Stuckert

Chemistry Faculty Publications

This report describes the results of research performed with funds from the Sture Fredrik Anliot Grant Fund granted in March 2016 and the Wright State University College of Science and Mathematics. The title of the grant was “Lytle Creek and Indian Run Sediment and Water Pollution Assessment” and its primary aim was to identify and measure pollutants that could be causing a lack of biodiversity in Lytle Creek in Wilmington, OH. The project formed the basis of Amira Alsenbel’s Masters in Chemistry thesis research.

March For Science - Dayton, Earth Day, Audrey E. Mcgowin

Chemistry Faculty Publications

March for Science speech given by Audrey McGowin, PhD in Dayton, Ohio on Earth Day 2017.

Water Quality In And Around Glen Helen Nature Preserve Fall 2016, Krista Baumgartner, Kellie Bohrer, Brandon Bresler, Thomas Chenault, Miriam Crane, Jennifer Dean, James Herbort, Kelsey Hood, Megan Shade, Kraig Strayer, Nicholas Yahana, Emily Warren, Ben Silliman, Brandon Myers, Steven Ujvary, Audrey E. Mcgowin

Chemistry Faculty Publications

No abstract provided.

Glen Helen Water Quality: A 5-Year Exploration, 2011-2015 (Acs), Audrey E. Mcgowin Ph.D.

Chemistry Faculty Publications

No abstract provided.

Glen Helen Water Quality: A 5-Year Exploration, 2011-2015, Audrey E. Mcgowin

Chemistry Faculty Publications

These slides are from my presentation at Green(e) Fest 2016 “Make Every Day Earth Day,” Glen Helen Association Annual Meeting. This is a summary of research results obtained by 50+ students enrolled in my Service-Learning Intensive Environmental Chemistry course at Wright State University. It includes recommendations to Glen Helen and the Village of Yellow Springs by the students regarding findings of high E. coli in stormwater runoff, high nitrate levels in groundwater, and violations of a foundry’s permit to discharge into Glen Helen.

Glen Helen And Little Miami River Water Quality Fall 2015, Steven J. Ujvary, Sarah Izor, Lin Phu, Lauren Bruce, Justin Myers, Jessica Clemmons, Amy Mcneely, Ashlynn Boedecker, Ritu Ghose, Jessica Mckinley, Audrey E. Mcgowin

Chemistry Faculty Publications

Service Learning Intensive (SVI) - a teaching and learning pedagogy that engages faculty, students, and community members in a partnership to achieve academic learning objectives, meet community needs, promote civic responsibility, and reflect on the learning experience.

More specifically, the objectives for this course are for students to:

• Apply environmental chemistry concepts learned in the classroom to the interpretation environmental analysis results

• Use Good Laboratory Practice (GLP) through the use of Standard Operating Procedures (SOPs) and EPA methods for the analysis of metals, anions, dissolved oxygen, pH, temperature, conductivity, ammonia, and turbidity

• Follow up on previous years’ results showing elevated …

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Final Report: Storm Water Pollutant Inputs To The Little Miami River Via Yellow Springs And Birch Creeks, Audrey E. Mcgowin

Chemistry Faculty Publications

This report describes the results of research performed with funds from the Sture Fredrik Anliot Grant Fund granted in March 2015. The primary aim of the project was to identify and measure various stormwater pollutant inputs to Yellow Springs Creek and Birch Creek into Glen Helen Nature Preserve and then into the Little Miami River in Greene County, Ohio from Spring 2015 to Winter 2016.

In order to better understand pollutant flow into Glen Helen and subsequently into the Little Miami River, three different types of samples were taken. One type of sample was a “grab” sample taken under normal …

Evaluation And Monitoring Of Glen Helen Water Quality Fall 2014, Nathaniel Brackett, Brannon Dunn, Robert Magley, Saagar M. Patel, Jennifer Purvis, Sarah R. Steele, Jonathan M. Tumey, Katie Watson, James K. Waweru, Benjamin Wick, Scott N. Atkinson, Audrey E. Mcgowin

Chemistry Faculty Publications

Poster describing the evaluation and monitoring of water quality in the Glen Helen Nature Preserve, Yellow Springs, Ohio, in the Fall of 2014.

An Analytical Look At Glen Helen Nature Preserve Fall 2013, Audrey E. Mcgowin, Seth W. Brittle, Jacob Doolin, Dustin Estridge, Anna Foote, Shannon Hennley, Megan Huddleson, Robert Johnson, Abraham Kemboi, Carlie Mcgrath, John Mcgrath, Renata Mitton, David Roland, Nicholas Rose

Chemistry Faculty Publications

No abstract provided.

Monitoring The Health Of Glen Helen Nature Preserve: Fall 2012 Sediment And Water, Audrey E. Mcgowin Ph.D., Triet Minh Truong

Chemistry Student Publications

This poster presents the results for environmental testing in Glen Helen by the Special Topics in Analytical Chemistry course at Wright State University under the direction of Professor Audrey McGowin in Spring 2012. Water quality data are presented for the Yellow Spring in Yellow Springs, Ohio for April and May of 2012. Other test sites range from locations along Yellow Springs Creek to the covered bridge near Little Miami River.

This poster was created by Triet M. Truong.

New Primers Reveal The Presence Of A Duplicate Histone H3 In The Marine Turtle Leech Ozobranchus Branchiatus, Triet Minh Truong, Audrey E. Mcgowin Ph.D., Philip Lavretsky, Jeffrey L. Peters Ph.D.

Chemistry Student Publications

Marine leeches, specific to sea turtles, have been implicated as potential vector organisms in the spread of fibropapillomatosis (FP), a pandemic neoplastic disease with green turtles (Chelonia mydas) having the highest affliction rate. Polymerase chain reaction identified two independent, seemingly functional histone H3 loci for marine turtle leeches Ozobranchus branchiatus collected from C. mydas in Florida and Hawaii. Primers were developed to amplify each product separately. These novel markers will be useful in identifying ectoparasites in FP research, evaluating other histone variants, and chromatin dynamics regulation studies.

This poster was created and presented by Triet M. Truong at the Wright …

Atmospheric Polycyclic Aromatic Hydrocarbon Profiles And Sources In Pine Needles And Particulate Matter In Dayton, Ohio, Usa, Timothy A. Tomashuk, Triet Minh Truong, Madhavi Mantha, Audrey E. Mcgowin Ph.D.

Chemistry Student Publications

Polycyclic aromatic hydrocarbons (PAHs) were measured in pine needles (passive sampling) and on high volume particulate matter (PM) filters (active sampling) over a period of eight to ten months at two separate sites in the Dayton, Ohio, USA metropolitan area: Moraine and Yellow Springs.

Total PAH concentrations for PM ranged from 77.4 μg/g to 837 μg/g (dry wt.) at both sites with high molecular weight PAHs being the predominant form that tended to be higher in concentration during the colder months. Total PAH concentrations for pine needles varied by tree species and location. With an average concentration of 4187 ng/g, …

Monitoring The Health Of Glen Helen Nature Preserve: Spring 2012 Sediment And Water, Audrey E. Mcgowin Ph.D., Triet Minh Truong, David Kammler Ph.D., Joe Solch

Chemistry Student Publications

This poster presents the results for environmental testing in Glen Helen by the Special Topics in Analytical Chemistry course at Wright State University under the direction of Professor Audrey McGowin in Spring 2012. Water quality data are presented for the Yellow Spring in Yellow Springs, Ohio for April and May of 2012. Other test sites range from locations along Yellow Springs Creek to the covered bridge near Little Miami River.

This poster was created by Triet M. Truong.

Monitoring The Health Of Glen Helen Nature Preserve: Can I Drink The Water?, David Kammler Ph.D., Triet Minh Truong, Garrett Vanness, Audrey E. Mcgowin Ph.D.

Chemistry Student Publications

This poster presents the results for water quality testing in Glen Helen by the Advanced Environmental Chemistry and Analysis course at Wright State University under the direction of Professor Audrey McGowin and the Global Seminar: Water course at Antioch College under the direction of Professor David Kammler in Fall 2011. Water quality data are presented for the Yellow Spring in Yellow Springs, Ohio for September, October, and November of 2011. Other test sites included Birch Creek and other sites along Yellow Springs Creek.

This poster was created and presented at the 3rd Annual Wright State University Campus-Wide Celebration of Research, …

Dna Barcoding Of Sea Turtle Leeches (Ozobranchus Spp.) In Florida Coastal Waters, Triet Minh Truong, Audrey E. Mcgowin Ph.D.

Chemistry Student Publications

Fibropapillomatosis (FP) is a neoplastic disease originally identified only on green sea turtles (Chelonia mydas). The disease is likely to be terminal if tumors are developed internally, but external tumors on the eyes, mouth, and flippers can also lead to fatal impairment of vision and difficulty feeding and swimming. The involvement of an environmental cofactor appears possible since many FP outbreaks occur at sites of poor water quality in Florida, Hawaii, Brazil, and other similar places around the world, but outbreaks have also been recorded at less contaminated sites. Studies have shown an association between FP and the fibropapilloma-associated turtle …

Identification Of Sea Turtle Leeches Using Dna Barcoding, Triet Minh Truong, Audrey E. Mcgowin Ph.D., Adrian M. Corbett Ph.D.

Chemistry Student Publications

Fibropapillomatosis (FP) is a panzootic plaguing all species of sea turtles with green turtles having the highest percentage of affliction. Although fibropapilloma-associated turtle herpes virus (FPTHV) has been identified as the causative agent of FP, the primary vector triggering this chronic tumor-forming disease is still unknown. Parasitic marine leeches (Ozobranchus spp.) could be a potential mechanical vector behind the emergence of this panzootic, although it is uncertain if it is species specific. Ozobranchus spp. are very small and difficult to distinguish anatomically, and until now, there have been few attempts to document them. DNA barcoding using mitochondrial cytochrome c oxidase …

Analysis Of Atmospheric Pahs In The Austrian Pine, Timothy Tomashuk, Triet Minh Truong, Audrey E. Mcgowin Ph.D.

Chemistry Student Publications

Polycyclic aromatic hydrocarbons (PAH) are a common pollutant created by natural (forest fires) or anthropogenic sources, such as incomplete combustion in engines (vehicular traffic) or incinerators. Many PAHs are known or suspected carcinogens and also have mutagenic properties and endocrine disrupting effects.

Although most atmospheric PAHs are measured using high-volume sample collection on filters, a convenient way of monitoring these pollutants is through plant matrices, such as pine needles that act as passive samplers. The needles are covered with a lipid-rich cuticle that absorbs the pollutants. Evergreens are especially useful because they continue to accumulate pollutants during the winter.

In …