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Full-Text Articles in Physical Sciences and Mathematics
Resources For Interdisciplinary Understanding Of Energy, Alessandra Hughes, Jessica Trottier
Resources For Interdisciplinary Understanding Of Energy, Alessandra Hughes, Jessica Trottier
Scholars Week
In most undergraduate curricula, students are expected to have the ability to apply, or transfer, a learned concept to new coursework. In the sciences, students are often introduced to energy ideas with discipline-specific vocabulary and tasks which encourage compartmentalized, surface-level understandings of energy concepts. Our research investigates student transfer of energy ideas within a coherent science course series, where physics is the foundational course. Similar modeling tools and vocabulary are used in the classes to help students see energy as a unifying framework. We seek to identify and describe what transfer “looks like” in this idealized context by interviewing students …
Temporal And Spatial Variability Of Carbonate Chemistry In A Tillamook Bay Tributary: Tracing Acidification From The River To The Bay, Abigail Ernest-Beck
Temporal And Spatial Variability Of Carbonate Chemistry In A Tillamook Bay Tributary: Tracing Acidification From The River To The Bay, Abigail Ernest-Beck
WWU Honors College Senior Projects
Coastal acidification from rising atmospheric carbon dioxide can be exacerbated by local factors such as land inputs of inorganic carbon and nutrients. In Tillamook Bay, OR, the possibility of local factors enhancing acidification and impacting oyster aquaculture in the bay is a concern due to extensive agriculture in the watershed. The US EPA has been monitoring water conditions in Tillamook Bay tributaries since the summer of 2016, and preliminary findings showed increased dissolved inorganic carbon (DIC) downstream of agricultural areas. To determine the causes of elevated DIC, changes attributed to land-based inputs must be distinguished from natural temporal variability and …
Synthesis Of An Archazolid Based Enzyme Inhibitor, Cooper A. Vincent
Synthesis Of An Archazolid Based Enzyme Inhibitor, Cooper A. Vincent
WWU Graduate School Collection
The archazolids are a family of natural products that display powerful growth inhibitory activity against a number of human cancer cell lines. This activity has been linked to inhibition of the vacuolar-type ATPase (V-ATPase) and more recently cyclooxygenase (COX) enzymes. Using the archazolid structure as a starting point, several simplified analogues have been prepared and assayed for their V-ATPase and COX inhibitory activity. These simplified analogues were prepared using a novel Suzuki coupling with yields over 80%. They were assayed to investigate both their V-ATPase and COX inhibitory activity. In our assays there was no COX inhibition, while there was …