Physical Sciences and Mathematics Commons^™

Westbound, Genevieve Nicolow

Honors Theses

Westbound is a twenty-five chapter novella that aims to demonstrate ways in which creative writers can use climate fiction to overcome psychological barriers to act on climate change. The narrative follows Cassie, a character loosely based on a relative of its author, living in a future version of the United States that has been ravaged by climate change and its indirect consequences.

In the novella, Cassie and her mother Nia set out on a cross-country road trip as a climate disaster looms. The narrative explores their relationship and that with Cassie’s estranged father, the implications of projected ecological changes under …

School District Boundaries Map, Nick Huffman

Honors Theses

The purpose of this project is to provide a school district boundary mapping feature to a product sold by Level Data called SDVS, which is a plugin used by districts inside of PowerSchool. Using primarily the features offered by Mapbox, We have implemented a React component that is capable of plotting useful data points related to a student and their school district on a map. The tool is designed to be used primarily by school administrators to determine whether or not a student lives within their district boundaries. The application uses a dataset that is provided by the NCES to …

Stem Teacher Database, Veronica Buss

Honors Theses

The College of Engineering and Applied Sciences (CEAS) Recruitment web application provides access to recruitment information for the Manager of Recruitment and Outreach and those who also use the spreadsheet file with their current data. This database is a functional database for the WMU college of engineering and applied sciences’ recruiters to organize their data on STEM teachers from the feeder high schools of WMU. The app provides an interface for its users to filter and search the data they have compiled to create recruitment mailing reports. The main purpose of this app was to facilitate the retrieval and upkeep …

Optimization Of Cation Exchange Chromatography Purification Of A Small Peptide: An Industrial And Practical Approach, Jamin Willoughby

Honors Theses

Ion exchange chromatography (IEX) is a common chemical separation technique that is used to separate ionizable target molecules from a liquid mixture mobile phase by adsorption of the molecule to a stationary phase. In chromatography, the stationary phase is a porous solid that the target molecule and mobile phase flows through, and is commonly referred to as the resin. Resins are commonly packed into hollow cylindrical columns. The mobile phase is the liquid solvent which flows through the column containing the stationary phase. The target molecule will have an affinity for the resin and adsorb to it, while impurities in …

Biological Evaluation Of Fda-Approved Drugs As Mirna-31 Inhibitors Using Real Time Qrt-Pcr And A Luciferase Assay, Nicholas Sienkiewicz

Honors Theses

MicroRNAs (miRNAs) are a group of post-transcriptional, negative regulators of gene expression, consisting of ~19-24 nucleotides. Since their discovery in 1993, miRNAs have been found to be involved in a diverse amount of cellular and disease pathways, including certain types of cancer. Overexpression of certain oncogenic miRNAs, including miRNA-31, have been shown to play a role in cancer cell development. Recent findings have suggested that miRNAs play a significant role in every stage of colorectal cancer (CRC) initiation, progression, and development, as well as induce resistance to chemotherapy drugs like 5-FU. In particular, research has shown that increased levels of …