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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Statistical Reanalysis Of Jewish Priests’ And Non-Priests’ Haplotypes Using Exact Methods, Shlomo S. Sawilowsky Jun 2011

Statistical Reanalysis Of Jewish Priests’ And Non-Priests’ Haplotypes Using Exact Methods, Shlomo S. Sawilowsky

Theoretical and Behavioral Foundations of Education Faculty Publications

Researchers in an article appearing in Nature used asymptotic (i.e., large sample) chi-square tests in analyzing haplotypes of Y chromosomes using the polymerase chain reaction applied to genomic DNA from male Israeli, North American, and British Jews. The use of classical methods for analyzing extremely sparse contingency tables is frequently done, but with the advent of statistical software capable of conducting exact tests, researchers should certainly cease relying on outdated methods for small sample analyses. A reanalysis was conducted using modern statistical methods. Results and implications for using exact tests are discussed.


Bias In Monte Carlo Simulations Due To Pseudo-Random Number Generator Initial Seed Selection, Jack C. Hill, Shlomo S. Sawilowsky May 2011

Bias In Monte Carlo Simulations Due To Pseudo-Random Number Generator Initial Seed Selection, Jack C. Hill, Shlomo S. Sawilowsky

Theoretical and Behavioral Foundations of Education Faculty Publications

Pseudo-random number generators can bias Monte Carlo simulations of the standard normal probability distribution function with initial seeds selection. Five generator designs were initial-seeded with values from 10000HEX to 1FFFFHEX, estimates of the mean were calculated for each seed, the distribution of mean estimates was determined for each generator and simulation histories were graphed for selected seeds.