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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Investigating Applications Of Deep Learning For Diagnosis Of Post Traumatic Elbow Disease, Hugh James Dec 2022

Investigating Applications Of Deep Learning For Diagnosis Of Post Traumatic Elbow Disease, Hugh James

McKelvey School of Engineering Theses & Dissertations

Traumatic events such as dislocation, breaks, and arthritis of musculoskeletal joints can cause the development of post-traumatic joint contracture (PTJC). Clinically, noninvasive techniques such as Magnetic Resonance Imaging (MRI) scans are used to analyze the disease. Such procedures require a patient to sit sedentary for long periods of time and can be expensive as well. Additionally, years of practice and experience are required for clinicians to accurately recognize the diseased anterior capsule region and make an accurate diagnosis. Manual tracing of the anterior capsule is done to help with diagnosis but is subjective and timely. As a result, there is …


Integrating Physical Models And Deep Priors For Computational Imaging, Yu Sun Aug 2022

Integrating Physical Models And Deep Priors For Computational Imaging, Yu Sun

McKelvey School of Engineering Theses & Dissertations

This dissertation addresses integrating physical models and learning priors for computational imaging. The motivation of our work is driven by the recent discussion of learning-based methods that solve the imaging inverse problem by directly learning a measurement-to-image mapping from the existing data: they achieve superior performance over the traditional model-based methods but lack the physical model to impose sufficient interpretation and guarantee of the final image. We adopt the classic statistical inference as the underlying formulation and integrate learning models as implicit image priors, such that our framework is able to simultaneously leverage physical models and learning priors. Additionally, the …


Development Of The Assessment Of Clinical Prediction Model Transportability (Apt) Checklist, Sean Chonghwan Yu Aug 2022

Development Of The Assessment Of Clinical Prediction Model Transportability (Apt) Checklist, Sean Chonghwan Yu

McKelvey School of Engineering Theses & Dissertations

Clinical Prediction Models (CPM) have long been used for Clinical Decision Support (CDS) initially based on simple clinical scoring systems, and increasingly based on complex machine learning models relying on large-scale Electronic Health Record (EHR) data. External implementation – or the application of CPMs on sites where it was not originally developed – is valuable as it reduces the need for redundant de novo CPM development, enables CPM usage by low resource organizations, facilitates external validation studies, and encourages collaborative development of CPMs. Further, adoption of externally developed CPMs has been facilitated by ongoing interoperability efforts in standards, policy, and …