Physical Sciences and Mathematics Commons^™

Translating -Omics Big Data: Comprehensive Understanding Of Host-Pathogen Interactions To Control Bacterial Blight In Alfalfa Using Computational Approaches, Raghav Kataria

Student Research Symposium

Plant infectious diseases are a major threat to the crops, owing to economic losses to the agriculture industry worldwide. Molecular interactions between the host and pathogen play a critical role in understanding the basis of pathogenesis. Majority of the Pseudomonas syringae strains are known to cause frost injury in plants, amongst which, P. syringae pv. syringae ALF3 is asserted to be a causal organism of bacterial stem blight in Medicago sativa (alfalfa). We elucidated the genome-scale host-pathogen interactions (HPIs) between alfalfa and P. syringae using two intense computational approaches: interolog (homology-based) and the domain-based method (based on 3D structure of …