Physical Sciences and Mathematics Commons^™

A Polarographic Study Of Selected Metal Complex Ions Of Several P-Tosyl Amino Acids, Joseph Martin Reyes

University of the Pacific Theses and Dissertations

A polarographic study of the complexes of selected metal ions and the p-Tosyl derivatives of the amino acids; glycine, glutamic acid and lysine has been made to determine their coordination number, formula, dissociation constant and free energy of formation.

A Study Of The Formation Of Cyclic Allenes From 2,3-Dibromocycloalkenes, Michael John Millam

University of the Pacific Theses and Dissertations

This investigation was undertaken in an attempt to form strained cyclic allenes and to study their chemistry. The method chosen for the attempted formation of strained cyclic allenes was the determination of the corresponding 2,3-dibromocycloalkene. 2,3-Dibromocyclononene was synthesized during the course of this investigation so that its debromination to the 1,2-cyclononadiene, which is the smallest stable, 1,2-cycloalkadiene, could be studies as model for the debromination of smaller 2,3-dibromocycloalkenes was initiated. The formation of 1,2-cyclohexadiene was attempted by the debromination of the 2,3-dibromocyclohexene. Evidence for the presence of this unstable intermediate was sought via the use of trapping agents.

Synthesis Of N-Methyl-D-Gulosamine And Methyl Ethers Of N-Methyl-D-Gulosamine, Hazrat Mohammed Noorzad

University of the Pacific Theses and Dissertations

A great variety of amino sugars has been found in antibiotics among these D-gulosamine in the striptomyces group. In the same group, .an N-methylated amino-sugar, N-methyl-L~ glucosamine has been isolated. Although N-methyl-0-gulosamine .has not been found in nature until now, its ultimate discovery would not be surprising in this context. In the present work this amino-sugar and some important derivatives are prepared for the first time, starting from D-glucosamine, a pure benzyl· 3-0-acetyl-2-benzyloxycarbonylamido-2-deoxy-~-D-glucopyranoside (X) was obtained by a series of kno~n processes. Benzyl 3-0-acetyl~-methylsulfonyl-2-deoxy-~-D-glucopyranoside (XIII) and some of its derivatives were obtaine.d from (X). An attempt was made to obtain …

The Synthesis Of Methyl-2-Acetamido-3,4,6-0-Triacetyl Alpha-D-Talosaminide, Mohammad Saleem Choudhary

University of the Pacific Theses and Dissertations

Amongst the very many different kinds of amino sugars, theones that have aroused the most interest are the 2-amino 2-deoxy hexoses which are found in such well known antibiotics as streptomycin and neomycine (2). There are so far about forty-three antibiotics which are known to contain different aminosugars (6).

Aminosugars exhibit the same properties as other reducing aldohexoses, e. g. reduction of silver and cupric salts, oxidation to hexonic acids, reduction to alcohols and formation of glycosides.

The object of this project is to synthesize methyl N-acetyl α-D-talosaminide which has previously been prepared by Jeanloz (3) following a different route. …

The Development Of Non-Emulsified Aerosol Foams And A Comparative Study Of Their Physical Properties, Dexter Earl Vollbrecht

University of the Pacific Theses and Dissertations

The introduction of the aerosol shaving lather stimulated widespread application of the aerosol foam as a new dosage form vehicle. Medication of different types has been incorporated into these aerosol foams and has been employed for both topical and oral administration.

Ternary Phase Diagram Determinations Concerning Potassium Electrolyte Influence On Aqueous Solutions Of Dioxane Or Tetrahydrofuran, John Albert Mcnaney

University of the Pacific Theses and Dissertations

For the graphical representation of the mutual, partial solubilities of a·ternary system, a diagram is generally employed which is based upon the equilateral triangle, whose properties are especially felicitous for this-purpose.

In this study, the phase diagrams for the following systems were determined: potassium acetate-water-dioxane, potassium acetate-water-tetrahydrofuran, potassium benzoate-water-dioxane, potassium benzoate-watertetrahydrofuran, potassium chloride-water-tetrahydrofuran, and potassium hydroxide-water-dioxane.

The systems, potassium acetate-water-dioxane and potassium hydroxidewater-dioxane, were investigated at 25° and 85°. This study indicates that they are, to a slight degree, temperature dependent. When these systems were plotted on a mole-percentage basis, it was found that both potassium compounds have about the …

Palladium And Platinum Complexes Of Substituted Cycloolefins, Gerald Brady Mccauley

University of the Pacific Theses and Dissertations

Much of the fundamental work on complexation of cycloolefins by platinum metals has been laid down by several workers and ranges from complexes of butadiene those of cyclododecatriene. The work here was chiefly a continuation of research on cycloolefin complexes which appear in papers by Kuljian and Frye (30,31,44). Most of this work on the complexes of cyclic seven, eight, and twelve carbon ligands was repeated here to insure a more complete laboratory background and for verification of previously reported literature data on these compounds. These compounds were used a s basis for comparison to original compounds developed in the …