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Full-Text Articles in Physical Sciences and Mathematics

Inulin-125I-Tyramine, An Improved Residualizing Label For Studies On Sites Of Catabolism Of Circulating Proteins, Janet L. Maxwell, John W. Baynes, Suzanne R. Thorpe Oct 1988

Inulin-125I-Tyramine, An Improved Residualizing Label For Studies On Sites Of Catabolism Of Circulating Proteins, Janet L. Maxwell, John W. Baynes, Suzanne R. Thorpe

Faculty Publications

Residualizing labels for protein, such as dilactitol-125I-tyramine (125I-DLT) and cellobiitol-125I-tyramine, have been used to identify the tissue and cellular sites of catabolism of long-lived plasma proteins, such as albumin, immunoglobulins, and lipoproteins. The radioactive degradation products formed from labeled proteins are relatively large, hydrophilic, resistant to lysosomal hydrolases, and accumulate in lysosomes in the cells involved in degradation of the carrier protein. However, the gradual loss of the catabolites from cells (t1/2 approximately 2 days) has limited the usefulness of residualizing labels in studies on longer lived proteins. We describe here a higher molecular weight (Mr approximately 5000), more efficient …


Subspaces Of Lp,Q, N L. Carothers, S J. Dilworth Oct 1988

Subspaces Of Lp,Q, N L. Carothers, S J. Dilworth

Faculty Publications

We examine the subspace structure of the Lorentz function space Lp,q[0, oo). Our main result is that a subspace of Lp,q[0, oo), p ^ 2, q < oo,must either strongly embed in Lp[0,1] or contain a complemented copy of lq.


Inequalities For Sums Of Independent Random Variables, N L. Carothers, S J. Dilworth Sep 1988

Inequalities For Sums Of Independent Random Variables, N L. Carothers, S J. Dilworth

Faculty Publications

A moment inequality is proved for sums of independent random variables in the Lorentz spaces LPtq, thus extending an inequality of Rosenthal. The latter result is used in combination with a square function inequality to give a proof of a Banach space isomorphism theorem. Further moment inequalities are also proved.


Oxidative Degradation Of Glucose Adducts To Protein: Formation Of 3-(NE-Lysino)-Lactic Acid From Model Compounds And Glycated Proteins, Mahtab U. Ahmed, John A. Dunn, Michael D. Walla, Suzanne R. Thorpe, John W. Baynes Jun 1988

Oxidative Degradation Of Glucose Adducts To Protein: Formation Of 3-(NE-Lysino)-Lactic Acid From Model Compounds And Glycated Proteins, Mahtab U. Ahmed, John A. Dunn, Michael D. Walla, Suzanne R. Thorpe, John W. Baynes

Faculty Publications

The chemistry of Maillard or browning reactions of glycated proteins is being studied in model systems in vitro in order to characterize potential reaction pathways and products in biological systems. In previous work with the Amadori rearrangement product N alpha-formyl-N epsilon-fructoselysine (fFL), an analog of glycated lysine residues in proteins, we showed that fFL was oxidatively cleaved between C-2 and C-3 of the carbohydrate chain to yield N epsilon-carboxymethyllysine (CML) and D-erythronic acid. We then detected CML in proteins glycated in vitro, as well as in human lens proteins and collagen in vivo (Ahmed, M. U., Thorpe, S. R., and …


Experimental Study Of Nonlinear Conductance In Small Metallic Samples, Richard A. Webb, S. Washburn, C. P. Umbach May 1988

Experimental Study Of Nonlinear Conductance In Small Metallic Samples, Richard A. Webb, S. Washburn, C. P. Umbach

Faculty Publications

We have directly observed current-dependent, nonlinear contributions to the conductance fluctuations of phase-coherent metallic wires and loops. The fluctuations in the current-voltage curves are reproducible, asymmetric about I=0, and in qualitative agreement with theoretical predictions. In ac measurements, the nonlinear terms also generate large harmonic signals of the conductance fluctuations whose dependence on the drive current can be understood qualitatively. The spectra of harmonics from loops and wires have different dependences on the voltage across the sample.


A Cytochemical Study Of The Transcriptional And Translational Regulation Of Nuclear Transition Protein 1 (Tp1), A Major Chromosomal Protein Of Mammalian Spermatids, Mohammad A. Heidaran, Richard M. Showman, Wilson Stephen Kistler May 1988

A Cytochemical Study Of The Transcriptional And Translational Regulation Of Nuclear Transition Protein 1 (Tp1), A Major Chromosomal Protein Of Mammalian Spermatids, Mohammad A. Heidaran, Richard M. Showman, Wilson Stephen Kistler

Faculty Publications

Immunocytochemical localization and in situ hybridization techniques were used to investigate the presence of spermatid nuclear transition protein 1 (TP1) and its mRNA during the various stages of spermatogenesis in the rat. A specific antiserum to TP1 was raised in a rabbit and used to show that TP1 is immunologically crossreactive among many mammals including humans. During spermatogenesis the protein appears in spermatids as they progress from step 12 to step 13, a period in which nuclear condensation is underway. The protein is lost during step 15. An asymmetric RNA probe generated from a TP1 cDNA clone identified TP1 mRNA …


Interpolation Of Besov-Spaces, Ronald A. Devore, Vasil A. Popova Jan 1988

Interpolation Of Besov-Spaces, Ronald A. Devore, Vasil A. Popova

Faculty Publications

We investigate Besov spaces and their connection with dyadic spline approximation in Lp(Omega), 0 < p (less than or equal to) infinity. Our main results are: the determination of the interpolation spaces between a pair of Besov spaces; an atomic decomposition for functions in a Besov space; the characterization of the class of functions which have certain prescribed degree of approximation by dyadic splines.


Hydrothermal Fluids And Petroleum In Surface Sediments Of Guaymas Basin, Gulf Of California: A Case Study, J. M. Gieskes, B. R. Simoneit, T. Brown, Timothy J. Shaw, Y. C. Wang, A. Magenheim Jan 1988

Hydrothermal Fluids And Petroleum In Surface Sediments Of Guaymas Basin, Gulf Of California: A Case Study, J. M. Gieskes, B. R. Simoneit, T. Brown, Timothy J. Shaw, Y. C. Wang, A. Magenheim

Faculty Publications

No abstract provided.


The Twentieth Fermat Number Is Composite, Jeff Young, Duncan A. Buell Jan 1988

The Twentieth Fermat Number Is Composite, Jeff Young, Duncan A. Buell

Faculty Publications

The twentieth Fermat number, F20 = 22^20 +1, has been proven composite by machine computation.


Involutions On Banach Spaces And Reflexivity, S J. Dilworth Jan 1988

Involutions On Banach Spaces And Reflexivity, S J. Dilworth

Faculty Publications

No abstract provided.