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From Cellular To Holistic: Development Of Algorithms To Study Human Health And Diseases, Casey Anne Cole
From Cellular To Holistic: Development Of Algorithms To Study Human Health And Diseases, Casey Anne Cole
Theses and Dissertations
The development of theoretical computational methods and their application has become widespread in the world today. In this dissertation, I present my work in the creation of models to detect and describe complex biological and health related problems. The first major part of my work centers around the creation and enhancement of methods to calculate protein structure and dynamics. To this end, substantial enhancement has been made to the software package REDCRAFT to better facilitate its usage in protein structure calculation. The enhancements have led to an overall increase in its ability to characterize proteins under difficult conditions such as …