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Full-Text Articles in Physical Sciences and Mathematics
Evidence For A Bind-Then-Bend Mechanism For Architectural Dna Binding Protein Ynhp6a, Manas Kumar Sarangi, Viktoriya Zvoda, Molly Nelson Holte, Nicole A. Becker, Justin Peters, L. James Maher Iii, Anjum Ansari
Evidence For A Bind-Then-Bend Mechanism For Architectural Dna Binding Protein Ynhp6a, Manas Kumar Sarangi, Viktoriya Zvoda, Molly Nelson Holte, Nicole A. Becker, Justin Peters, L. James Maher Iii, Anjum Ansari
Faculty Publications
The yeast Nhp6A protein (yNhp6A) is a member of the eukaryotic HMGB family of chromatin factors that enhance apparent DNA flexibility. yNhp6A binds DNA nonspecifically with nM affinity, sharply bending DNA by >60◦. It is not known whether the protein binds to unbent DNA and then deforms it, or if bent DNA conformations are ‘captured’ by protein binding. The former mechanism would be supported by discovery of conditions where unbent DNA is bound by yNhp6A. Here, we employed an array of conformational probes (FRET, fluorescence anisotropy, and circular dichroism) to reveal solution conditions in which an 18- base-pair DNA oligomer …
Structure And Magnetism Of Nifemngaxsn1-X (X=0, 0.25, 0.5, 0.75, 1.00) Heusler Compounds, Jace Waybright, Lee Halbritter, Bishnu Dahal, Hanyang Qian, Yung Huh, Pavel Lukashev, Parashu Kharel
Structure And Magnetism Of Nifemngaxsn1-X (X=0, 0.25, 0.5, 0.75, 1.00) Heusler Compounds, Jace Waybright, Lee Halbritter, Bishnu Dahal, Hanyang Qian, Yung Huh, Pavel Lukashev, Parashu Kharel
Faculty Publications
The crystal structure and magnetic properties of NiFeMnGaxSn1-x (x = 0, 0.25, 0.50, 0.75 and 1.00) Heusler compounds have been investigated experimentally and theoretically. The computational results suggest that NiFeMnGa0.75Sn0.25 is nearly half-metallic with a spin polarization P of 87%. The bulk samples prepared using arc-melting and annealing exhibit a high degree of Y-type order. All the investigated samples show ferromagnetic spin order with the Curie temperatures ranging from 284 K for NiFeMnGa to 408 K for NiFeMnSn. The intermediate composition NiFeMnGa0.75Sn0.25, which is predicted to be nearly half metallic, …