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Periodontitis And Gestational Diabetes Mellitus: A Systematic Review And Meta-Analysis Of Observational Studies, Samuel A. Abariga, Brian W. Whitcomb
Periodontitis And Gestational Diabetes Mellitus: A Systematic Review And Meta-Analysis Of Observational Studies, Samuel A. Abariga, Brian W. Whitcomb
Biostatistics and Epidemiology Faculty Publications Series
Background: Gestational diabetes mellitus (GDM) is glucose intolerance with first onset during pregnancy and is associated with serious maternal and fetal complications. The etiology of GDM is not well understood, but systemic inflammation effects on insulin signaling and glucose metabolism is suspected. Periodontal disease is a chronic inflammatory condition that induces local and host immune responses and has been evaluated for a potential role in development of GDM. Results from studies evaluating the association between periodontitis and GDM are mixed. We performed a systematic review and meta-analysis to summarize available data regarding the association between periodontitis and GDM.
Methods: Twelve …