Physical Sciences and Mathematics Commons^™

Joint Map Of Hardin County, Kentucky, Steven L. Martin, Emily Morris

Map and Chart--KGS

New field mapping of joints with previously published joint and fault locations. This fracture map can be used as a critical data source for hydrological, karst or geotechnical applications. Joint orientations were measured in 2009, 2022 and 2023, and are combined with joint and fault locations for Hardin County, Kentucky from 1:24,000-scale USGS geologic quadrangle maps that were published from 1962 to 1977. The geologic quadrangle maps for the county were digitized from 2002 to 2007.

The geology of Hardin County consists of Upper Devonian New Albany Shale overlain by Lower to Upper Mississippian-age sequences of limestone, dolomite, sandstone and …

Surficial Geologic Map Of The Summit 7.5-Minute Quadrangle, Kentucky, Antonia E. Bottoms, Ann Hislop, Matthew A. Massey, Max Hammond Iii, Michelle Mchugh, Emily Morris

Report of Investigations--KGS

The Summit 7.5-minute quadrangle is located south of Louisville and west of Elizabethtown along the boundary between Hardin and Grayson Counties and within the Mississippian Plateau physiographic region (McDowell, 1986). Topography is characterized by the low relief Pennyroyal region that sits at elevations between 560 to 650 ft above sea level, the low relief Mammoth Cave plateau at elevations between 750 to 900 ft, and the steep Dripping Springs escarpment that separates the two plains. Moore (1964) mapped the bedrock geology of the quadrangle, which was later digitized by Conley (2002). Mississippian bedrock is exposed throughout the quadrangle and is …

Phase I Activities Of The Earth Mapping Resources Initiative (Earth Mri) In The Western Kentucky Fluorspar District, Georgina Lukoczki, Craig Dietsch, John B. Hickman, Emily Morris, Douglas C. Curl, Carrie Pulliam, Stephanie Vicroy, William M. Andrews Jr.

Report of Investigations--KGS

The Western Kentucky Fluorspar District (WKFD), which comprises the Kentucky portion of the Illinois–Kentucky Fluorspar District, is well known for the occurrence of strategically important critical mineral resources, such as fluorite (fluorspar) and rare earth elements (REEs). Due to technological advances, demand has increased for critical minerals used in cell phones, magnets in wind turbines, batteries for electric vehicles, smart weapons, and other devices and systems. The overall objective of the Earth Mapping Resources Initiative (Earth MRI) program, directed by the U.S. Geological Survey (USGS), is to gather information that will help better understand the distribution of critical minerals in …

Physical Activity Barriers And Assets In Rural Appalachian Kentucky: A Mixed-Methods Study, Natalie Jones, Deirdre Dlugonski, Rachel Gillespie, Emily M. Dewitt, Joann Lianekhammy, Stacey A. Slone, Kathryn M. Cardarelli

Sports Medicine Research Institute Faculty Publications

Obesity is an increasing public health concern in the U.S. and a contributor to chronic illness, with trends revealing a rise in adult obesity and chronic disease rates among the most vulnerable and disadvantaged populations, including those in rural communities. A mixed-methods approach was used to examine perspectives on perceived physical activity barriers, resources, and level of community support. Researchers utilized the socioecological model to examine the multiple domains that support physical activity in rural Appalachia. The present study focuses on baseline data, including a cohort survey to assess physical activity, health status, and barriers to physical activity, and five …

Covid-19 And The Impact On Rural And Black Church Congregants: Results Of The C-M-C Project, Lovoria B. Williams, Anita F. Fernander, Tofial Azam, Maria L. Gomez, Junghee Kang, Cassidy L. Moody, Hannah Bowman, Nancy E. Schoenberg

Nursing Faculty Publications

The COVID-19 pandemic has had devastating effects on Black and rural populations with a mortality rate among Blacks three times that of Whites and both rural and Black populations experiencing limited access to COVID-19 resources. The primary purpose of this study was to explore the health, financial, and psychological impact of COVID-19 among rural White Appalachian and Black nonrural central Kentucky church congregants. Secondarily we sought to examine the association between sociodemographics and behaviors, attitudes, and beliefs regarding COVID-19 and intent to vaccinate. We used a cross sectional survey design developed with the constructs of the Health Belief and Theory …

Cardiovascular Complications Of Systemic Lupus Erythematosus: Impact Of Risk Factors And Therapeutic Efficacy--A Tertiary Centre Experience In An Appalachian State, Elise Danielle Mcveigh, Amna Batool, Arnold J. Stromberg, Ahmed K. Abdel-Latif, Nayef Mohammed Kazzaz

Statistics Faculty Publications

OBJECTIVES: Cardiovascular complications became a notable cause of morbidity and mortality in patients with lupus as therapeutic advancements became more efficient at managing other complications. The Appalachian community in Kentucky has a higher prevalence of traditional cardiovascular risk factors, predisposing them to cardiovascular events. Namely, the mean body mass index of the members of the Kentucky Appalachian community was reported at 33 kg/m² and 94.3% of male members of this community use tobacco. We sought to identify risk factors that predispose patients with lupus to cardiovascular morbidities and examine the effect of immunomodulatory drugs.

METHODS: We identified 20 UKHS …

Development Of Mine Soils In A Chronosequence Of Forestry-Reclaimed Sites In Eastern Kentucky, Kenton L. Sena, Kevin M. Yeager, Christopher D. Barton, John M. Lhotka, William E. Bond, Kimberly J. Schindler

Lewis Honors College Faculty Publications

Surface mining for coal has contributed to widespread deforestation and soil loss in coal mining regions around the world, and particularly in Appalachia, USA. Mined land reforestation is of interest in this and other regions where forests are the dominant pre-mining land use. This study evaluated mine soil development on surface-mined sites reforested according to the Forestry Reclamation Approach, representing a chronosequence of time ranging from 0 to 19 years after reclamation. Soils were sampled in depth increments to 50 cm and analyzed for a suite of soil physical and chemical characteristics. Overall, soil fines (silt + clay) tended to …

Bundles And Hotspots Of Multiple Ecosystem Services For Optimized Land Management In Kentucky, United States, Yang Bai, Thomas O. Ochuodho, Jian Yang, Domena A. Agyeman

Forestry and Natural Resources Faculty Publications

Ecosystem services are benefits that the natural environment provides to support human well-being. A thorough understanding and assessment of these services are critical to maintain ecosystem services flow through sustainable land management to optimize bundles of ecosystem services provision. Maximizing one particular ecosystem service may lead to reduction in another. Therefore, identifying ecosystem services tradeoffs and synergies is key in addressing this challenge. However, the identification of multiple ecosystem services tradeoffs and synergies is still limited. A previous study failed to effectively capture the spatial interaction among ecosystem services as it was limited by “space-to-time” substitution method used because of …

Dach1 Mutation Frequency In Endometrial Cancer Is Associated With High Tumor Mutation Burden, Mckayla J. Riggs, Nan Lin, Chi Wang, Dava W. Piecoro, Rachel W. Miller, Oliver A. Hampton, Mahadev Rao, Frederick R. Ueland, Jill M. Kolesar

Obstetrics and Gynecology Faculty Publications

OBJECTIVE: DACH1 is a transcriptional repressor and tumor suppressor gene frequently mutated in melanoma, bladder, and prostate cancer. Loss of DACH1 expression is associated with poor prognostic features and reduced overall survival in uterine cancer. In this study, we utilized the Oncology Research Information Exchange Network (ORIEN) Avatar database to determine the frequency of DACH1 mutations in patients with endometrial cancer in our Kentucky population.

METHODS: We obtained clinical and genomic data for 65 patients with endometrial cancer from the Markey Cancer Center (MCC). We examined the clinical attributes of the cancers by DACH1 status by comparing whole-exome sequencing (WES), …

Geochemistry, Petrology, And Palynology Of The Princess No. 3 Coal, Greenup County, Kentucky, Madison M. Hood, Cortland F. Eble, James C. Hower, Shifeng Dai

Center for Applied Energy Research Faculty and Staff Publications

The high volatile C bituminous-rank, Bolsovian-age Princess No. 3 coal, a correlative of the heavily-mined Hazard No. 7 coal and the Peach Orchard and Coalburg Lower Split coals, was investigated three sites at a mine in Greenup County, Kentucky. The coal exhibits a “dulling upwards” trend, with decreasing vitrinite and a greater tendency towards dull clarain and bone lithotypes towards the top of the coal. The relatively vitrinite-rich basal lithotype is marked by a dominance of lycopod tree spores. The palynology transitions upwards to a middle parting co-dominated by tree fern and small lycopod spores and an upper bench dominated …

A Geologically Based Indoor-Radon Potential Map Of Kentucky, William C. Haneberg, Amanda T. Wiggins, Douglas C. Curl, Stephen F. Greb, William M. Andrews Jr., Kathy Rademacher, Mary Kay Rayens, Ellen J. Hahn

Faculty, Staff, and Affiliated Publications--KGS

We combined 71,930 short-term (median duration 4 days) home radon test results with 1:24,000-scale bedrock geologic map coverage of Kentucky to produce a statewide geologically based indoor-radon potential map. The test results were positively skewed with a mean of 266 Bq/m³, median of 122 Bq/m³, and 75th percentile of 289 Bq/m³. We identified 106 formations with ≥10 test results. Analysis of results from 20 predominantly monolithologic formations showed indoor-radon concentrations to be positively skewed on a formation-by-formation basis, with a proportional relationship between sample means and standard deviations. Limestone (median 170 Bq/m³) …

Rare Earth-Bearing Particles In Fly Ash Carbons: Examples From The Combustion Of Eastern Kentucky Coals, James C. Hower, John G. Groppo Jr.

Center for Applied Energy Research Faculty and Staff Publications

Graphitic carbons from the combustion of bituminous coals and, perhaps, other coal ranks, tend to capture iron and a number of hazardous elements, including As, Hg, and Se. Rare earth elements in fly ashes occur in minerals, such as monazite, xenotime, and davidite. They also occur in sub-nm particles, probably in a mineral form, within the Al–Si glass on the investigated fly ashes. Just as graphitic carbons can capture Fe and hazardous elements, the carbons surrounding the fly ash glass and magnetic particles captures or encapsulates a broad suite of rare earth elements.

Occupancy And Abundance Of Stream Salamanders Along A Specific Conductance Gradient, Jacob M. Hutton, Steven J. Price, Simon J. Bonner, Stephen C. Richter, Christopher D. Barton

Forestry and Natural Resources Faculty Publications

In the Central Appalachians (USA), mountaintop-removal mining accompanied by valley fills often leads to streams with elevated specific conductivity (SC). Thus, the ionic composition of freshwaters in this region is hypothesized to be a driver of the distribution and abundance of freshwater taxa, including stream salamanders. We examined the association between SC and stream salamander populations by conducting salamander counts in 30 southeastern Kentucky streams across a continuous gradient of SC that ranged from 30 to 1966 μS/cm. We counted 2319 salamanders across 5 species and, using a hierarchical Bayesian version of the N-mixture model, found a negative association between …

Predicting And Mapping Plethodontid Salamander Abundance Using Lidar-Derived Terrain And Vegetation Characteristics, Marco Antonio Contreras, Wesley A. Staats, Steve J. Price

Forestry and Natural Resources Faculty Publications

Aim of the study: Use LiDAR-derived vegetation and terrain characteristics to develop abundance and occupancy predictions for two terrestrial salamander species, Plethodon glutinosus and P. kentucki, and map abundance to identify vegetation and terrain characteristics affecting their distribution.

Area of study: The 1,550-ha Clemons Fork watershed, part of the University of Kentucky’s Robinson Forest in southeastern Kentucky, USA.

Materials and methods: We quantified the abundance of salamanders using 45 field transects, which were visited three times, placed across varying soil moisture and canopy cover conditions. We created several LiDAR-derived vegetation and terrain layers and used these …

Recent Shrinkage And Fragmentation Of Bluegrass Landscape In Kentucky, Bo Tao, Yanjun Yang, Jia Yang, S. Ray Smith, James F. Fox, Alex C. Ruane, Jinze Liu, Wei Ren

Plant and Soil Sciences Faculty Publications

The Bluegrass Region is an area in north-central Kentucky with unique natural and cultural significance, which possesses some of the most fertile soils in the world. Over recent decades, land use and land cover changes have threatened the protection of the unique natural, scenic, and historic resources in this region. In this study, we applied a fragmentation model and a set of landscape metrics together with the satellite-derived USDA Cropland Data Layer to examine the shrinkage and fragmentation of grassland in the Bluegrass Region, Kentucky during 2008–2018. Our results showed that recent land use change across the Bluegrass Region is …

Influence Of Timber Harvesting Operations And Streamside Management Zone Effectiveness On Sediment Delivery To Headwater Streams In Appalachia, Daniel Bowker, Jeffrey W. Stringer, Christopher D. Barton

Forestry and Natural Resources Faculty Publications

Disturbances created by timber harvesting equipment and associated haul roads and skid trails can create overland sediment flows (sediment paths), especially in steeply sloping terrain, leading to stream sedimentation. This study investigated the effect of variables associated with GPS tracked harvest equipment movement, skid trail development and retirement, topography, and streamside management zone (SMZ) width and tree retention on sediment delivery to streams. While the intensity of harvest equipment traffic was not correlated with sediment path development, the presence and location of skid trails were. All of the sediment paths were found to originate at water control structures, influenced by …

Geologic Characterization, Hydrologic Monitoring, And Soil-Water Relationships For Landslides In Kentucky, Matthew M. Crawford, L. Sebastian Bryson, Zhenming Wang, Edward W. Woolery

Report of Investigations--KGS

Complex spatial and temporal variables control the movement of water through colluvial soils in hillslopes. Some of the factors that influence soil-moisture fluctuation are soil type, thickness, porosity and permeability, and slope morphology. Landslide-characterization and field-monitoring techniques were part of a method to connect hydrologic and geotechnical data in order to monitor long-term hydrologic conditions in three active landslides in Kentucky, establish hydrologic relationships across the slope, and analyze specific soil-water relationships that can predict shear strength. Volumetric water content, water potential, and electrical conductivity were measured between October 2015 and February 2019. The duration and magnitude of drying and …

Enhancing Timeliness Of Drug Overdose Mortality Surveillance: A Machine Learning Approach, Patrick J. Ward, Peter J. Rock, Svetla Slavova, April M. Young, Terry L. Bunn, Ramakanth Kavuluru

Kentucky Injury Prevention and Research Center Faculty Publications

BACKGROUND: Timely data is key to effective public health responses to epidemics. Drug overdose deaths are identified in surveillance systems through ICD-10 codes present on death certificates. ICD-10 coding takes time, but free-text information is available on death certificates prior to ICD-10 coding. The objective of this study was to develop a machine learning method to classify free-text death certificates as drug overdoses to provide faster drug overdose mortality surveillance.

METHODS: Using 2017–2018 Kentucky death certificate data, free-text fields were tokenized and features were created from these tokens using natural language processing (NLP). Word, bigram, and trigram features were created …

Mineralogy And Chemistry Of Rare Earth Elements In Alkaline Ultramafic Rocks And Fluorite In The Western Kentucky Fluorspar District, Warren H. Anderson

Report of Investigations--KGS

Rare earth elements, or REE, are used in modern society in televisions, computers, cellphones, military equipment, and smart weapons systems. These metals are also used by the medical industry in magnetic resonance imaging and in medical products.

The igneous rocks in the Western Kentucky Fluorspar District of the New Madrid Rift System are considered alkaline ultramafic rocks that are slightly enriched in REE. These rocks are rare and only occur in several hundred locations in the world. They have a complex history of emplacement, fractionation, metasomatism, and alteration, and are overprinted with Mississippi Valley-type mineralization. They are classified as lamprophyres …

Tobacco Smoking And Dementia In A Kentucky Cohort: A Competing Risk Analysis, Erin L. Abner, Peter T. Nelson, Gregory A. Jicha, Gregory E. Cooper, David W. Fardo, Frederick A. Schmitt, Richard J. Kryscio

Epidemiology and Environmental Health Faculty Publications

Tobacco smoking was examined as a risk for dementia and neuropathological burden in 531 initially cognitively normal older adults followed longitudinally at the University of Kentucky’s Alzheimer’s Disease Center. The cohort was followed for an average of 11.5 years; 111 (20.9%) participants were diagnosed with dementia, while 242 (45.6%) died without dementia. At baseline, 49 (9.2%) participants reported current smoking (median pack-years = 47.3) and 231 (43.5%) former smoking (median pack-years = 24.5). The hazard ratio (HR) for dementia for former smokers versus never smokers based on the Cox model was 1.64 (95% CI: 1.09, 2.46), while the HR for …

Using Watershed Pour-Point Elevations To Evaluate The Base Of Fresh Groundwater In The Cumberland Plateau Of Eastern Kentucky, Ethan S. L. Davis, Thomas M. Parris, Jerrad Grider

Report of Investigations--KGS

Horizontal drilling with hydraulic fracturing at shallow depths (less than 2,200 ft) in the Devonian Berea Sandstone oil and gas play, along with the potential for high-volume hydraulic fracturing in the nascent Cambrian Rogersville Shale gas play, have generated a renewed interest in protecting groundwater quality in eastern Kentucky. A critical component of protection is an accurate understanding of the distribution of fresh water in the subsurface. The “Fresh-Saline Water Interface Map of Kentucky” by H.T. Hopkins, published by the U.S. Geological Survey and Kentucky Geological Survey in 1966, has been a critical reference for assessing the maximum depth of …

Impact Of The Affordable Care Act On Colorectal Cancer Screening, Incidence, And Survival In Kentucky, Tong Gan, Heather F. Sinner, Samuel C. Walling, Quan Chen, Bin Huang, Thomas C. Tucker, Jitesh A. Patel, B. Mark Evers, Avinash S. Bhakta

Surgery Faculty Publications

Background

Kentucky ranks first in the US in cancer incidence and mortality. Compounded by high poverty levels and a high rate of medically uninsured, cancer rates are even worse in Appalachian Kentucky. Being one of the first states to adopt the Affordable Care Act (ACA) Medicaid expansion, insurance coverage markedly increased for Kentucky residents. The purpose of our study was to determine the impact of Medicaid expansion on colorectal cancer (CRC) screening, diagnosis, and survival in Kentucky.

Study Design

The Kentucky Cabinet for Health and Family Services and the Kentucky Cancer Registry were queried for individuals (≥20 years) undergoing CRC …

A Parent-Led Intervention To Promote Recovery Following Pediatric Injury: Study Protocol For A Randomized Controlled Trial, Meghan L. Marsac, Ginny Sprang, Leila Guller, Kristen L. Kohser, John M. Draus Jr., Nancy Kassam-Adams

Pediatrics Faculty Publications

Background: Injury is one of the most prevalent potentially emotionally traumatic events that children experience and can lead to persistent impaired physical and emotional health. There is a need for interventions that promote full physical and emotional recovery and that can be easily accessed by all injured children. Based on research evidence regarding post-injury recovery, we created the Cellie Coping Kit for Children with Injury intervention to target key mechanisms of action and refined the intervention based on feedback from children, families, and experts in the field. The Cellie Coping Kit intervention is parent-guided and includes a toy (for engagement), …

Characteristics Of Cover-Collapse Sinkholes In Kentucky, James C. Currens

Report of Investigations--KGS

Sudden collapse of unconsolidated earth materials over soluble bedrock, known as cover collapse, damages buildings, roads, utility lines, and farm equipment in Kentucky. It has also killed livestock, including Thoroughbred horses, and injured people. The estimated annual cost of sinkhole cover collapse in Kentucky ranges from $20 million to $84 million and is sensitive to rare but expensive events such as the 2014 National Corvette Museum collapse. The Kentucky Geological Survey began developing a catalog of case histories of cover-collapse occurrences in 1997, and receives an average of 24 reports each year. Three hundred fifty-four occurrences of cover-collapse sinkholes throughout …

Ground Motions Induced By The March 11, 2018, Implosion Of The Capital Plaza Tower, Frankfort, Kentucky, N. Seth Carpenter, Michael J. Lynch, Brandon C. Nuttall, Zhenming Wang, Andrew S. Holcomb

Report of Investigations--KGS

The demolition by implosion of the Capital Plaza Tower in downtown Frankfort provided an opportunity to record seismic waves from a known source of seismic energy in order to observe local ground-motion amplification and resonance within the underlying unconsolidated sediment. The Kentucky Geological Survey deployed three strong-motion accelerographs at approximately equal distances around the tower to record ground motions induced by its collapse. The KGS instruments were installed at sites with different underlying geology: one on bedrock and two on Kentucky River Valley unconsolidated sediments.

Using images captured by a high-speed video camera, with timing synchronized with the clock of …

Zircon U-Pb Geochronology Of Two Basement Cores (Kentucky, Usa): Implications For Late Mesoproterozoic Sedimentation And Tectonics In The Eastern Midcontinent, David P. Moecher, J. Richard Bowersox, John B. Hickman

Earth and Environmental Sciences Faculty Publications

Basement cores from two wells drilled west and east of the Grenville front consist of feldspathic litharenite and granitic orthogneiss, respectively. Detrital zircon U-Pb ages for the litharenite define a broad dominant U-Pb age mode at ca. 1115 Ma. The dominant mode matches that for the type locality of the Middle Run Formation in the Ohio subsurface and is interpreted to consist of detrital zircons sourced from East Continent Rift volcanic sources (ca. 1100 Ma) and Grenville Shawinigan granites/gneisses (1120–1180 Ma). The youngest detrital zircon ages (ca. 1020 Ma) require a maximum depositional age that is at least 70 My …

Mccrearamycins A-D, Geldanamycin-Derived Cyclopentenone Macrolactams From An Eastern Kentucky Abandoned Coal Mine Microbe, Xiachang Wang, Yinan Zhang, Larissa V. Ponomareva, Qingchao Qiu, Ryan M. Woodcock, Sherif I. Elshahawi, Xiabin Chen, Ziyuan Zhou, Bruce E. Hatcher, James C. Hower, Chang-Guo Zhan, Sean Parkin, Madan K. Kharel, S. Randal Voss, Khaled A. Shaaban, Jon S. Thorson

Center for Pharmaceutical Research and Innovation Faculty Publications

Four cyclopentenone‐containing ansamycin polyketides (mccrearamycins A–D), and six new geldanamycins (Gdms B–G, including new linear and mycothiol conjugates), were characterized as metabolites of Streptomyces sp. AD‐23‐14 isolated from the Rock Creek underground coal mine acid drainage site. Biomimetic chemical conversion studies using both simple synthetic models and Gdm D confirmed that the mccrearamycin cyclopentenone derives from benzilic acid rearrangement of 19‐hydroxy Gdm, and thereby provides a new synthetic derivatization strategy and implicates a potential unique biocatalyst in mccrearamycin cyclopentenone formation. In addition to standard Hsp90α binding and cell line cytotoxicity assays, this study also highlights the first assessment of Hsp90α …

Field Investigation Of An Active Landslide In Kentucky: A Framework To Correlate Electrical Data And Shear Strength, Matthew M. Crawford, L. Sebastian Bryson

Report of Investigations--KGS

Landslide hazard assessments are best accomplished by a multidisciplinary approach that connects geologic processes with geotechnical behavior. Tools to accomplish this in the field include geologic characterization, hydrologic monitoring, and geophysical surveys, and in the laboratory, soil-strength testing. Volumetric water content, soil-water potential (suction), local rainfall, and in situ electrical conductivity were measured at a shallow colluvial landslide in Kentucky. Surface electrical-resistivity surveys were also conducted to support interpretations of depth to failure, lithologic differences, and changes in moisture content over time. Correlations of hydrologic data with electrical measurements and shear strength indicate that observed changes in the degree of …

Performance Of Endophyte Infected Tall Fescue In Europe And North America, Kari Saikkonen, Timothy D. Phillips, Stanley H. Faeth, Rebecca L. Mcculley, Irma Saloniemi, Marjo Helander

Plant and Soil Sciences Faculty Publications

Human assisted plant invasions from Europe to North America have been more common than the reverse. We tested endophyte-mediated performance of tall fescue in parallel three year experiments in Europe and the USA using endophyte infected and uninfected wild and cultivated plants. Experimental plants were subjected to nutrient and water treatments. Whereas endophyte infection increased tall fescue performance in general, the effects of endophytes on plant growth and reproduction varied among plant origins under different environmental conditions. Naturally endophyte-free Finnish cultivar ‘Retu’ performed equally well as ‘Kentucky-31’ in both geographic locations. All Eurasian origin plants performed well in the US. …

Correlation Of Maximal Inspiratory Pressure To Transdiaphragmatic Twitch Pressure In Intensive Care Unit Patients, Gerald S. Supinski, Philip M. Westgate, Leigh Ann Callahan

Internal Medicine Faculty Publications

Background: Respiratory muscle weakness contributes to respiratory failure in ICU patients. Unfortunately, assessment of weakness is difficult since the most objective test, transdiaphragmatic pressure in response to phrenic nerve stimulation (PdiTw), is difficult to perform. While most clinicians utilize maximum inspiratory pressure (Pimax) to assess strength, the relationship of this index to PdiTw has not been evaluated in a large ICU population. The purpose of the present study was to assess both PdiTw and Pimax in ICU patients to determine how these indices correlate with each other, what factors influence these indices, and how well these indices predict outcomes.

Methods: …