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Simulation Of T2 Mri Relaxation Enhancement By Magnetic Nanoparticles, Yahia Adeeb Tawfiq Hamdan
Simulation Of T2 Mri Relaxation Enhancement By Magnetic Nanoparticles, Yahia Adeeb Tawfiq Hamdan
Physics Theses
The effect of high concentration of magnetic nanoparticles (MNP) on Magnetic Resonance Imaging (MRI) transverse relaxation rates (R2=1/T2 and R2*=1/T2*) were studied using Monte Carlo (MC) simulations. Theoretical models assume that particle occupies a small volume fraction of the sample space. This work aims to test if available models based on Motional Averaged (MAR) and Static Dephasing Regimes (SDR) can still represent relaxation rates at large volume fractions. Furthermore, echo-time effects were tested on both gradient-echo and spin-echo sequences in order to examine if diffusion is involved. Findings will clarify if models need …