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Full-Text Articles in Physical Sciences and Mathematics
Computational And Biological Studies Of Novel Thiazolyl Coumarin Derivatives Synthesized Through Suzuki Coupling, Shaista Parveen, Saima Kalsoom, Rifhat Bibi, Ambreen Asghar, Abdul Hameed, Waqar Ahmed, Abbas Hassan
Computational And Biological Studies Of Novel Thiazolyl Coumarin Derivatives Synthesized Through Suzuki Coupling, Shaista Parveen, Saima Kalsoom, Rifhat Bibi, Ambreen Asghar, Abdul Hameed, Waqar Ahmed, Abbas Hassan
Turkish Journal of Chemistry
The current investigation presents the synthesis, computational molecular-docking and biological activity studies of arylated thiazole coumarins. Aryl substituted thiazolyl coumarin derivatives were synthesized via Suzuki cross-coupling reaction. A detailed reaction condition optimization revealed that the Pd-PEPPSI-IPent precatalyst in only 2 mol% loading resulted in the desired product with high yield. The aim of this study was to examine the antimicrobial behavior of thiazole coumarin derivatives through in vitro and in silico studies. All the compounds showed activity against both antibacterial strains, Staphylococcus aureus and Escherichia coli, except 5d. Similarly, the compounds 5a, 5b, and 5d were found to be active …
Bioreduction: The Biological Activity, Characterization, And Synthesis Of Silver Nanoparticles, Nesri̇n Korkmaz
Bioreduction: The Biological Activity, Characterization, And Synthesis Of Silver Nanoparticles, Nesri̇n Korkmaz
Turkish Journal of Chemistry
Today, nanoparticles are effectively used in different areas. Initially, physical and chemical methods were used in the synthesis of nanoparticles. Biosynthesis (green synthesis) has emerged as an alternative to overcome the toxic effects of chemically synthesized nanoparticles. In this study, green synthesis of silver nanoparticles (AgNPs) with the leaf extract of Anthurium andraeanum was performed. UV-Vis spectrophotometry, scanning transmission electron microscopy, and XRD were applied to characterize the biosynthesized nanoparticles. As a result of the characterization, the spectra showed that a spectrum at a wavelength of about 419 nm and a spherical size of 38 nm nanoparticles was formed. Antibacterial …