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Full-Text Articles in Physical Sciences and Mathematics
Intrinsically Fluorescent And Quercetin Loaded Highly Crosslinked Polyphosphazene Nanospheres: Synthesis, Characterization And Fluorescence Properties, Si̇mge Meti̇noğlu Örüm
Intrinsically Fluorescent And Quercetin Loaded Highly Crosslinked Polyphosphazene Nanospheres: Synthesis, Characterization And Fluorescence Properties, Si̇mge Meti̇noğlu Örüm
Turkish Journal of Chemistry
Highly crosslinked, inorganic-organic hybrid and intrinsically fluorescent polyphosphazene nanospheres bearing hydroxyl groups on the surface are facilely generated via a one-pot polycondensation of octachlorocyclotetraphosphazene, fluorescein and quercetin. The resulting nanospheres were characterised by scanning electron microscopy (SEM), energy-dispersive X-ray analysis (EDX), Fourier transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), X-ray diffraction analysis (XRD) and ultraviolet-visible spectroscopy (UV-vis) techniques. The average diameter of the nanospheres was determined as 379 nm. Also, quercetin which is both a monomer and an anticancer drug was loaded to the nanospheres as 446 mg g-1. The obtained nanospheres possess outstanding disperse ability in both aqueous …
The Investigation Of Fluorescence And Metal Interaction Properties Of Racemic 7,8,9,10-Tetrahydro-3-Hydroxy-4-(1-Hydroxyethyl)Benzo[C]Chromen-6-One, Hayretti̇n Ozan Gülcan, Kharar Tawfeeq Shukur, Açelya Mavi̇deni̇z, Okan Si̇rkeci̇oğlu, Mustafa Gazi̇
The Investigation Of Fluorescence And Metal Interaction Properties Of Racemic 7,8,9,10-Tetrahydro-3-Hydroxy-4-(1-Hydroxyethyl)Benzo[C]Chromen-6-One, Hayretti̇n Ozan Gülcan, Kharar Tawfeeq Shukur, Açelya Mavi̇deni̇z, Okan Si̇rkeci̇oğlu, Mustafa Gazi̇
Turkish Journal of Chemistry
The design or investigation of fluorescence probes continues to receive attention with respect to the diverse applications of spectrofluorometry. Depending on the highly sensitive character, fluorescence spectroscopy-based methodologies have been widely used in recent years in different sciences, including analytical, environmental, and medicinal chemistry areas. In our previous works, we have shown the iron (III) selective on-off sensor properties of benzo[c]chromen-6-one derivatives. In this study, we have extrapolated this research to 4-substituted analogues and investigated both fluorescent and metal interaction properties. Following the synthesis and structure identification studies, (±)-7,8,9,10-tetrahydro-3-hydroxy-4-(1-hydroxyethyl)benzo[c]chromen-6-one was found as a fluorescent molecule displaying fluorescence enhancement in the …
Development Of Dual Enzyme Responsive Molecular And Logic Gate, Sündüs Erbaş Çakmak
Development Of Dual Enzyme Responsive Molecular And Logic Gate, Sündüs Erbaş Çakmak
Turkish Journal of Chemistry
Molecular logic gates are information processing devices that can respond to environmental signals and produce a readable output in response through Boolean logic operations. Molecules with these properties have been used to build smart sensors and therapeutic agents. In this work, dual enzyme-responsive molecular AND logic gate is developed with the intention to discriminate various combinations of enzyme level and/or activity. A resorufin-based sensor is substituted with self-immolative tyrosinase recognition site, 3-hydroxy benzyl group. The Hydroxyl group is protected with acetyl moiety which decreases the affinity of the enzyme. When both tyrosinase and esterase are present in the solution, the …