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Smith College

Chemistry: Faculty Publications

2004

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Full-Text Articles in Physical Sciences and Mathematics

Tandem Intramolecular Nicholas And Pauson-Khand Reactions For The Synthesis Of Tricyclic Oxygen-Containing Heterocycles, Miriam M. Quintal, Kristina D. Closser, Kevin M. Shea Nov 2004

Tandem Intramolecular Nicholas And Pauson-Khand Reactions For The Synthesis Of Tricyclic Oxygen-Containing Heterocycles, Miriam M. Quintal, Kristina D. Closser, Kevin M. Shea

Chemistry: Faculty Publications

Simple acyclic enynes can be easily converted into tricyclic ethers upon treatment with Co2(CO)8followed by Nicholas and Pauson−Khand reactions. Tricyclic [5,8,5]- and [5,7,5]-systems can be prepared in high overall yields in only seven synthetic steps.