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Modeling And Optimal Control Of A Nonlinear Dynamical System In Microbial Fed-Batch Fermentation Process, Chongyang Liu, Zhaohua Gong, Enmin Feng

Chongyang Liu

The mathematical model and optimal control of microbial fed-batch fermentation is considered in this paper. Since it is decisive for increasing the productivity of 1,3-propanediol (1,3-PD) to optimize the feeding rate of glycerol and the switching instants between the batch and feeding processes in the fermentation process, we propose a new nonlinear dynamical system to formulate the process. In the system, the switching instants are variable and the feeding rate of glycerol is regarded as the control function. Some important properties of the proposed system and its solution are then discussed. To maximize the concentration of 1,3-PD at the terminal …