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Full-Text Articles in Physical Sciences and Mathematics
Structure And Interactions Of Lipid Bilayers: Role Of Fluctuations, John F. Nagle, Stephanie Tristram-Nagle
Structure And Interactions Of Lipid Bilayers: Role Of Fluctuations, John F. Nagle, Stephanie Tristram-Nagle
Prof. Stephanie Tristram-Nagle Ph.D.
The cell is the fundamental unit in biology. Each cell is spatially defined by its cytoplasmic membrane. The structural basis for each membrane is lipid in bilayer form. Following this reductionist point of view, it is therefore not surprising that lipid bilayers have been much studied using a great variety of techniques.
X-Ray Structure, Thermodynamics, Elastic Properties And Mdsimulations Of Cardiolipin/Dimyristoylphosphatidylcholine Mixedmembranes, Alex Boscia, Bradley Treece, Dariush Mohammadyani, Judith Klein-Seetharaman, Anthony Braun, Beate Kloesgen, Tsjerk Wassenaar, Stephanie Tristram-Nagle
X-Ray Structure, Thermodynamics, Elastic Properties And Mdsimulations Of Cardiolipin/Dimyristoylphosphatidylcholine Mixedmembranes, Alex Boscia, Bradley Treece, Dariush Mohammadyani, Judith Klein-Seetharaman, Anthony Braun, Beate Kloesgen, Tsjerk Wassenaar, Stephanie Tristram-Nagle
Prof. Stephanie Tristram-Nagle Ph.D.
tCardiolipins (CLs) are important biologically for their unique role in biomembranes that couple phos-phorylation and electron transport like bacterial plasma membranes, chromatophores, chloroplasts andmitochondria. CLs are often tightly coupled to proteins involved in oxidative phosphorylation. The firststep in understanding the interaction of CL with proteins is to obtain the pure CL structure, and the struc-ture of mixtures of CL with other lipids. In this work we use a variety of techniques to characterize the fluidphase structure, material properties and thermodynamics of mixtures of dimyristoylphosphatidylcholine(DMPC) with tetramyristoylcardiolipin (TMCL), both with 14-carbon chains, at several mole percentages.X-ray diffuse scattering was used to …