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Articles 1 - 12 of 12
Full-Text Articles in Physical Sciences and Mathematics
Physical And Structural Basis For The Strong Interactions Of The -Impy- Central Pairing Motif In The Polyamide F-Impyim, K. Buchmueller, S. Bailey, D. Matthews, Z. Taherbhai, J. Register, Z. Davis, Chrystal Bruce, C. O'Hare, J. Hartley, M. Lee
Physical And Structural Basis For The Strong Interactions Of The -Impy- Central Pairing Motif In The Polyamide F-Impyim, K. Buchmueller, S. Bailey, D. Matthews, Z. Taherbhai, J. Register, Z. Davis, Chrystal Bruce, C. O'Hare, J. Hartley, M. Lee
Chrystal D. Bruce
The polyamide f-ImPyIm has a higher affinity for its cognate DNA than either the parent analogue, distamycin A (10-fold), or the structural isomer, f-PyImIm (250-fold), has for its respective cognate DNA sequence. These findings have led to the formulation of a two-letter polyamide “language” in which the -ImPy- central pairings associate more strongly with Watson−Crick DNA than -PyPy-, -PyIm-, and -ImIm-. Herein, we further characterize f-ImPyIm and f-PyImIm, and we report thermodynamic and structural differences between -ImPy- (f-ImPyIm) and -PyIm- (f-PyImIm) central pairings. DNase I footprinting studies confirmed that f-ImPyIm is a stronger binder than distamycin A and f-PyImIm and …
The Localized Dynamics Of A Ca2+Channel (30-Minute Talk), Borbala Mazzag, Christoper Tignanelli, Gregory D. Smith
The Localized Dynamics Of A Ca2+Channel (30-Minute Talk), Borbala Mazzag, Christoper Tignanelli, Gregory D. Smith
Borbala Mazzag
No abstract provided.
How Earth Remote Sensing From The International Space Station Complements Current Satellite‐Based Sensors, Jennifer Gebelein, Dean Eppler
How Earth Remote Sensing From The International Space Station Complements Current Satellite‐Based Sensors, Jennifer Gebelein, Dean Eppler
Jennifer Gebelein
The International Space Station (ISS) will provide an Earth‐and space‐observing platform that will support sensors built by 16 different countries and deliver data and images for local, regional and global research. When complete, it will be an exceptional platform for conducting remote sensing of the Earth, astrophysics, and space physics research programmes. Additionally, the ISS will operate as a testbed for engineering studies and complex technological developments that will benefit future Earth‐observing capabilities. ...
Bi-Level Clustering Of Mixed Categorical And Numerical Biomedical Data, Bill Andreopoulos, Aijun An, Xiaogang Wang
Bi-Level Clustering Of Mixed Categorical And Numerical Biomedical Data, Bill Andreopoulos, Aijun An, Xiaogang Wang
William B. Andreopoulos
Homeland Security: Engaging The Frontlines - Symposium Proceedings, George H. Baker, Cheryl J. Elliott
Homeland Security: Engaging The Frontlines - Symposium Proceedings, George H. Baker, Cheryl J. Elliott
George H Baker
The rise of the American homeland security endeavor under the leadership of the new Department of Homeland Security has been heralded by several major national strategy documents. These documents have served to organize efforts at top levels within the government and industry. However, the national strategy guidance is not getting to many organizations and people at the grass-roots level who can make the most difference in preventing attacks, protecting systems, and recovering from catastrophic events, viz. the general citizenry, private infrastructure owners, and local governments. To better understand grass-roots issues and solutions, James Madison University, in cooperation with the Federal …
Biochemical Characterization Of The Major Sorghum Grain Peroxidase, Mamoudou H. Dicko, Harry Gruppen, Riet Hilhorst, Alphons G. J. Voragen, Willen W. H. Van Berkel
Biochemical Characterization Of The Major Sorghum Grain Peroxidase, Mamoudou H. Dicko, Harry Gruppen, Riet Hilhorst, Alphons G. J. Voragen, Willen W. H. Van Berkel
Pr. Mamoudou H. DICKO, PhD
Functional Connectivity In A Baseline Resting-State Network In Autism, Vladimir Cherkassky, Rajesh Kana, Timothy Keller, Marcel Just
Functional Connectivity In A Baseline Resting-State Network In Autism, Vladimir Cherkassky, Rajesh Kana, Timothy Keller, Marcel Just
Marcel Adam Just
No abstract provided.
Comparison Of Virulence Gene Profiles Between Escherichia Coli Strains Isolated From Healthy And Diarrheic Swine, Mark Wilson, Karl A Bettelheim, X Y Wu, S Driesen, James Chin, Toni Chapman, I Barchia, D Trott
Comparison Of Virulence Gene Profiles Between Escherichia Coli Strains Isolated From Healthy And Diarrheic Swine, Mark Wilson, Karl A Bettelheim, X Y Wu, S Driesen, James Chin, Toni Chapman, I Barchia, D Trott
Mark R Wilson
No abstract provided.
Brain Correlates Of Discourse Processing: An Fmri Investigation Of Irony And Conventional Metaphor Comprehension, Zohar Eviatar, Marcel Adam Just
Brain Correlates Of Discourse Processing: An Fmri Investigation Of Irony And Conventional Metaphor Comprehension, Zohar Eviatar, Marcel Adam Just
Marcel Adam Just
No abstract provided.
Sentence Comprehension In Autism: Thinking In Pictures With Decreased Functional Connectivity, Rajesh K. Kana, Timothy A. Keller, Vladimir L. Cherkassky, Nancy J. Minshew, Marcel Adam Just
Sentence Comprehension In Autism: Thinking In Pictures With Decreased Functional Connectivity, Rajesh K. Kana, Timothy A. Keller, Vladimir L. Cherkassky, Nancy J. Minshew, Marcel Adam Just
Marcel Adam Just
No abstract provided.
Neural Basis Of Dyslexia: A Comparison Between Dyslexic And Non-Dyslexic Children Equated For Reading Ability, Fumiko Hoeft, Arvel Hernandez, Glenn Mcmillon, Heather Taylor-Hill, Jennifer L. Martindale, Ann Meyler, Timothy A. Keller, Wai Ting Siok, Gayle K. Deutsch, Marcel Adam Just, Susan Whitfield-Gabrieli, John D. E. Gabrieli
Neural Basis Of Dyslexia: A Comparison Between Dyslexic And Non-Dyslexic Children Equated For Reading Ability, Fumiko Hoeft, Arvel Hernandez, Glenn Mcmillon, Heather Taylor-Hill, Jennifer L. Martindale, Ann Meyler, Timothy A. Keller, Wai Ting Siok, Gayle K. Deutsch, Marcel Adam Just, Susan Whitfield-Gabrieli, John D. E. Gabrieli
Marcel Adam Just
No abstract provided.
Exchange Coupling And Contribution Of Induced Orbital Angular Momentum Of Low-Spin Fe^3+ Ions To Magnetic Anisotropy In Cyanide-Bridged Fe2m2 Molecular Magnets: Spin-Polarized Density-Functional Calculations, Stephen Holmes, Kyungwha Park
Exchange Coupling And Contribution Of Induced Orbital Angular Momentum Of Low-Spin Fe^3+ Ions To Magnetic Anisotropy In Cyanide-Bridged Fe2m2 Molecular Magnets: Spin-Polarized Density-Functional Calculations, Stephen Holmes, Kyungwha Park
Stephen Holmes