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Full-Text Articles in Physical Sciences and Mathematics
The Processing Pathway Of Prelamin A, Michael Sinensky, K. Fantle, M. Trujillo, T. Mclain, A. Kupfer, M. Dalton
The Processing Pathway Of Prelamin A, Michael Sinensky, K. Fantle, M. Trujillo, T. Mclain, A. Kupfer, M. Dalton
Faculty Publications, Biological Sciences
The conversion of mammalian prelamin A to mature lamin A proceeds through the removal of 18 amino acids from the carboxyl terminus. The initial step in this processing is the isoprenylation of a CAAX box cysteine. This proteolytic event is distinctive for prelamin A among the known prenylated mammalian proteins. Since the carboxyl terminus of prelamin A is removed during maturation, it is not obvious that this protein would undergo the two reactions subsequent to prenylation observed in other CAAX box proteins-the endoproteolytic removal of the carboxyl-terminal 3 amino acids and the subsequent methylation of the now carboxyl-terminal cysteine. To …
Direct Simulation Monte Carlo For Thin Film Bearings, Alejandro Garcia, B. Alder, F. J. Alexander
Direct Simulation Monte Carlo For Thin Film Bearings, Alejandro Garcia, B. Alder, F. J. Alexander
Faculty Publications
The direct simulation Monte Carlo (DSMC) scheme is used to study the gas flow under a read/write head positioned nanometers above a moving disk drive platter (the slider bearing problem). In most cases, impressive agreement is found between the particle-based simulation and numerical solutions of the continuum hydrodynamic Reynolds equation which has been corrected for slip. However, at very high platter speeds the gas is far from equilibrium, and the load capacity for the slider bearing cannot be accurately computed from the hydrodynamic pressure.
Microscopic Simulation Of Dilute Gases With Adjustable Transport Coefficients, Alejandro Garcia, F. Baras, M. Malek Mansour
Microscopic Simulation Of Dilute Gases With Adjustable Transport Coefficients, Alejandro Garcia, F. Baras, M. Malek Mansour
Faculty Publications
The Bird algorithm is a computationally efficient method for simulating dilute gas flows. However, due to the relatively large transport coefficients at low densities, high Rayleigh or Reynolds numbers are difficult to achieve by this technique. We present a modified version of the Bird algorithm in which the relaxation processes are enhanced and the transport coefficients reduced, while preserving the correct equilibrium and nonequilibrium fluid properties. The present algorithm is found to be two to three orders of magnitude faster than molecular dynamics for simulating complex hydrodynamical flows.
Expression Of Prelamin A Confers Sensitivity Of Dna Biosynthesis To Lovastatin On F9 Teratocarcinoma Cells, Michael Sinensky, T. Mclain, K. Fantle
Expression Of Prelamin A Confers Sensitivity Of Dna Biosynthesis To Lovastatin On F9 Teratocarcinoma Cells, Michael Sinensky, T. Mclain, K. Fantle
Faculty Publications, Biological Sciences
No abstract provided.
Direct Simulation Monte Carlo For Thin Film Bearings, Alejandro Garcia, B. Alder, F. J. Alexander
Direct Simulation Monte Carlo For Thin Film Bearings, Alejandro Garcia, B. Alder, F. J. Alexander
Alejandro Garcia
The direct simulation Monte Carlo (DSMC) scheme is used to study the gas flow under a read/write head positioned nanometers above a moving disk drive platter (the slider bearing problem). In most cases, impressive agreement is found between the particle-based simulation and numerical solutions of the continuum hydrodynamic Reynolds equation which has been corrected for slip. However, at very high platter speeds the gas is far from equilibrium, and the load capacity for the slider bearing cannot be accurately computed from the hydrodynamic pressure.
Microscopic Simulation Of Dilute Gases With Adjustable Transport Coefficients, Alejandro Garcia, F. Baras, M. Malek Mansour
Microscopic Simulation Of Dilute Gases With Adjustable Transport Coefficients, Alejandro Garcia, F. Baras, M. Malek Mansour
Alejandro Garcia
The Bird algorithm is a computationally efficient method for simulating dilute gas flows. However, due to the relatively large transport coefficients at low densities, high Rayleigh or Reynolds numbers are difficult to achieve by this technique. We present a modified version of the Bird algorithm in which the relaxation processes are enhanced and the transport coefficients reduced, while preserving the correct equilibrium and nonequilibrium fluid properties. The present algorithm is found to be two to three orders of magnitude faster than molecular dynamics for simulating complex hydrodynamical flows.