Physical Sciences and Mathematics | Open Access Articles

Stratospheric Variability And Trends In Models Used For The Ipcc Ar4, P. M. De F. Forster, Eugene Cordero

Faculty Publications, Meteorology and Climate Science

Atmosphere and ocean general circulation model (AOGCM) experiments for the Intergovernmental Panel on Climate Change Fourth Assessment Report (AR4) are analyzed to better understand model variability and assess the importance of various forcing mechanisms on stratospheric trends during the 20th century. While models represent the climatology of the stratosphere reasonably well in comparison with NCEP reanalysis, there are biases and large variability among models. In general, AOGCMs are cooler than NCEP throughout the stratosphere, with the largest differences in the tropics. Around half the AOGCMs have a top level beneath ~2 hPa and show a significant cold bias in their …

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Assessment Of Temperature, Trace Species, And Ozone In Chemistry-Climate Model Simulations Of The Recent Past, V. Eyring, N. Butchart, D. W. Waugh, H. Akiyoshi, J. Austin, S. Bekki, G. E. Bodeker, B. A. Boville, C. Brühl, M. P. Chipperfield, E. Cordero, M. Dameris, M. Deushi, V. E. Fioletov, S. M. Frith, R. R. Garcia, A. Gettelman, M. A. Giorgetta, V. Grewe, L. Jourdain, D. E. Kinnison, E. Mancini, E. Manzini, M. Marchand, D. R. Marsh, T. Nagashima, P. A. Newman, J. E. Nielsen, S. Pawson, G. Pitari, D. A. Plummer, E. Rozanov, M. Schraner, T. G. Shepherd, K. Shibata, R. S. Stolarski, H. Struthers, W. Tian, M. Yoshiki

Faculty Publications, Meteorology and Climate Science

[1] Simulations of the stratosphere from thirteen coupled chemistry-climate models (CCMs) are evaluated to provide guidance for the interpretation of ozone predictions made by the same CCMs. The focus of the evaluation is on how well the fields and processes that are important for determining the ozone distribution are represented in the simulations of the recent past. The core period of the evaluation is from 1980 to 1999 but long-term trends are compared for an extended period (1960–2004). Comparisons of polar high-latitude temperatures show that most CCMs have only small biases in the Northern Hemisphere in winter and spring, but …

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Bi-Level Clustering Of Mixed Categorical And Numerical Biomedical Data, Bill Andreopoulos, Aijun An, Xiaogang Wang

Faculty Publications, Computer Science

Biomedical data sets often have mixed categorical and numerical types, where the former represent semantic information on the objects and the latter represent experimental results. We present the BILCOM algorithm for |Bi-Level Clustering of Mixed categorical and numerical data types|. BILCOM performs a pseudo-Bayesian process, where the prior is categorical clustering. BILCOM partitions biomedical data sets of mixed types, such as hepatitis, thyroid disease and yeast gene expression data with Gene Ontology annotations, more accurately than if using one type alone.

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Introducing Semantics In Web Personalization: The Role Of Ontologies, Magdalini Eirinaki, Dimitrios Mavroeidis, George Tsatsaronis, Michalis Vazirgiannis

Faculty Publications

Web personalization is the process of customizing a web site to the needs of each specific user or set of users. Personalization of a web site may be performed by the provision of recommendations to the users, high-lighting/adding links, creation of index pages, etc. The web personalization systems are mainly based on the exploitation of the navigational patterns of the web site’s visitors. When a personalization system relies solely on usage-based results, however, valuable information conceptually related to what is finally recommended may be missed. The exploitation of the web pages’ semantics can considerably improve the results of web usage …

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Farnesylated Lamins, Progeroid Syndromes And Farnesyl Transferase Inhibitors, Michael Sinensky, A. E. Rusinol

Faculty Publications, Biological Sciences

Three mammalian nuclear lamin proteins, lamin B1, lamin B2 and the lamin A precursor, prelamin A, undergo canonical farnesylation and processing at CAAX motifs. In the case of prelamin A, there is an additional farnesylation-dependent endoproteolysis, which is defective in two congenital diseases: Hutchinson-Gilford progeria (HGPS) and restrictive dermopathy (RD). These two diseases arise respectively from defects in the prelamin A substrate and the enzyme (ZmpSte24) that processes it. Recent work has shed light on the roles of the lamin proteins and the enzymes involved in their farnesylation-dependent maturation. Other experimental work, including mouse model studies, have examined the possibility …

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Dna Damage Responses In Progeroid Syndromes Arise From Defective Maturation Of Prelamin A, Michael Sinensky, Y. Liu, A. Rusinol, Y. Wang, Y. Zou

Faculty Publications, Biological Sciences

The genetic diseases Hutchinson-Gilford progeria syndrome (HGPS) and restrictive dermopathy (RD) arise from accumulation of farnesylated prelamin A because of defects in the lamin A maturation pathway. Both of these diseases exhibit symptoms that can be viewed as accelerated aging. The mechanism by which accumulation of farnesylated prelamin A leads to these accelerated aging phenotypes is not understood. Here we present evidence that in HGPS and RD fibroblasts, DNA damage checkpoints are persistently activated because of the compromise in genomic integrity. Inactivation of checkpoint kinases Ataxia-telangiectasia-mutated (ATM) and ATR (ATM- and Rad3-related) in these patient cells can partially overcome their …

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Hydrodynamic Description Of The Adiabatic Piston, Alejandro Garcia, M. M. Mansour

Faculty Publications

A closed macroscopic equation for the motion of the two-dimensional adiabatic piston is derived from standard hydrodynamics. It predicts a damped oscillatory motion of the piston towards a final rest position, which depends on the initial state. In the limit of large piston mass, the solution of this equation is in quantitative agreement with the results obtained from both hard disk molecular dynamics and hydrodynamics. The explicit forms of the basic characteristics of the piston’s dynamics, such as the period of oscillations and the relaxation time, are derived. The limitations of the theory’s validity, in terms of the main system …

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Estimating Hydrodynamic Quantities In The Presence Of Microscopic Fluctuations, Alejandro Garcia

Faculty Publications

This paper discusses the evaluation of hydrodynamic variables in the presence of spontaneous fluctuations, such as in molecular simulations of fluid flows. The principal point is that hydrodynamic variables such as fluid velocity and temperature must be defined in terms of mechanical variables such as momentum and energy density). Because these relations are nonlinear and because fluctuations of mechanical variables are correlated, care must be taken to avoid introducing a bias when evaluating means, variances, and correlations of hydrodynamic variables. The unbiased estimates are formulated; some alternative, incorrect approaches are presented as cautionary warnings. The expressions are verified by numerical …

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A Deep Kinematic Survey Of Planetary Nebulae In The Andromeda Galaxy Using The Planetary Nebula Spectrograph, H. R. Merrett, M. R. Merrifield, N. G. Douglas, K. Kuijken, Aaron J. Romanowsky, N. R. Napolitano, M. Arnaboldi, M. Capaccioli, K. C. Freeman, O. Gerhard, L. Coccato, D. Carter, N. W. Evans, M. I. Wilkinson, C. Halliday, T. J. Bridges

Faculty Publications

We present a catalogue of positions, magnitudes and velocities for 3300 emission-line objects found by the Planetary Nebula Spectrograph in a survey of the Andromeda galaxy, M31. Of these objects, 2615 are found likely to be planetary nebulae (PNe) associated with M31. The survey area covers the whole of M31's disc out to a radius of Graphic. Beyond this radius, observations have been made along the major and minor axes, and the Northern Spur and Southern Stream regions. The calibrated data have been checked for internal consistency and compared with other catalogues. With the exception of the very central, high …

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Planetary Nebula Velocities In The Disc And Bulge Of M31, C. Halliday, D. Carter, T. J. Bridges, Z. C. Jackson, M. I. Wilkinson, D. P. Quinn, N. W. Evans, N. G. Douglas, H. R. Merrett, Aaron J. Romanowsky, K. Kuijken, M. J. Irwin

Faculty Publications

We present radial velocities for a sample of 723 planetary nebulae in the disc and bulge of M31, measured using the WYFFOS fibre spectrograph on the William Herschel Telescope. Velocities are determined using the [O III] λ5007 emission line. Rotation and velocity dispersion are measured to a radius of 50 arcmin (11.5 kpc), the first stellar rotation curve and velocity dispersion profile for M31 to such a radius. Our kinematics are consistent with rotational support at radii well beyond the bulge effective radius of 1.4 kpc, although our data beyond a radius of 5 kpc are limited. We present tentative …

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Wide-Field Kinematics Of Globular Clusters In The Leo I Group, G. Bergond, S. E. Zepf, Aaron J. Romanowsky, R. M. Sharples, K. L. Rhode

Faculty Publications

We present wide-field spectroscopy of globular clusters around the Leo I group galaxies NGC 3379 and NGC 3384 using the FLAMES multi-fibre instrument at the VLT. We obtain accurate radial velocities for 42 globular clusters (GCs) in total, 30 for GCs around the elliptical NGC 3379, eight around the lenticular NGC 3384, and four which may be associated with either galaxy. These data are notable for their large radial range extending from 0$\farcm$7 to 14$\farcm$5 (2 to 42 kpc) from the centre of NGC 3379, and small velocity uncertainties of about 10 km s-1. We combine our sample of 30 …

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The Araucaria Project. An Accurate Distance To Ngc 6822 From Near-Infrared Photometry Of Cepheid Variables, W. Gieren, G. Pietrzyński, K. Nalewajko, I. Soszyński, F. Bresolin, R.-P. Kudritzki, D. Minniti, Aaron J. Romanowsky

Faculty Publications

We have measured near-infrared magnitudes in the J and K bands for 56 Cepheid variables in the Local Group galaxy NGC 6822 with well-determined periods and optical light curves in the V and I bands. Using the template light-curve approach of Soszyński and coworkers, accurate mean magnitudes were obtained from these data, which allowed us to determine with unprecedented accuracy the distance to NGC 6822 from a multiwavelength period-luminosity solution in the VIJK bands. From our data, we obtain a distance to NGC 6822 of (m - M)0 = 23.312 ± 0.021 (random error) mag, with an additional systematic uncertainty …

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Full-Text Articles in Physical Sciences and Mathematics

Stratospheric Variability And Trends In Models Used For The Ipcc Ar4, P. M. De F. Forster, Eugene Cordero

Faculty Publications, Meteorology and Climate Science

Faculty Publications, Meteorology and Climate Science

Bi-Level Clustering Of Mixed Categorical And Numerical Biomedical Data, Bill Andreopoulos, Aijun An, Xiaogang Wang

Faculty Publications, Computer Science

Introducing Semantics In Web Personalization: The Role Of Ontologies, Magdalini Eirinaki, Dimitrios Mavroeidis, George Tsatsaronis, Michalis Vazirgiannis

Faculty Publications

Farnesylated Lamins, Progeroid Syndromes And Farnesyl Transferase Inhibitors, Michael Sinensky, A. E. Rusinol

Faculty Publications, Biological Sciences

Dna Damage Responses In Progeroid Syndromes Arise From Defective Maturation Of Prelamin A, Michael Sinensky, Y. Liu, A. Rusinol, Y. Wang, Y. Zou

Faculty Publications, Biological Sciences

Hydrodynamic Description Of The Adiabatic Piston, Alejandro Garcia, M. M. Mansour

Faculty Publications

Estimating Hydrodynamic Quantities In The Presence Of Microscopic Fluctuations, Alejandro Garcia

Faculty Publications

Faculty Publications

Planetary Nebula Velocities In The Disc And Bulge Of M31, C. Halliday, D. Carter, T. J. Bridges, Z. C. Jackson, M. I. Wilkinson, D. P. Quinn, N. W. Evans, N. G. Douglas, H. R. Merrett, Aaron J. Romanowsky, K. Kuijken, M. J. Irwin

Faculty Publications

Wide-Field Kinematics Of Globular Clusters In The Leo I Group, G. Bergond, S. E. Zepf, Aaron J. Romanowsky, R. M. Sharples, K. L. Rhode

Faculty Publications

The Araucaria Project. An Accurate Distance To Ngc 6822 From Near-Infrared Photometry Of Cepheid Variables, W. Gieren, G. Pietrzyński, K. Nalewajko, I. Soszyński, F. Bresolin, R.-P. Kudritzki, D. Minniti, Aaron J. Romanowsky

Faculty Publications